BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1284 related articles for article (PubMed ID: 17945434)

  • 1. Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.
    Peng Y; Lee DY; Jiang L; Ma Z; Schachter SC; Lemere CA
    Neuroscience; 2007 Dec; 150(2):386-95. PubMed ID: 17945434
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of huperzine A on amyloid precursor protein processing and beta-amyloid generation in human embryonic kidney 293 APP Swedish mutant cells.
    Peng Y; Jiang L; Lee DY; Schachter SC; Ma Z; Lemere CA
    J Neurosci Res; 2006 Sep; 84(4):903-11. PubMed ID: 16862548
    [TBL] [Abstract][Full Text] [Related]  

  • 3. L-3-n-butylphthalide regulates amyloid precursor protein processing by PKC and MAPK pathways in SK-N-SH cells over-expressing wild type human APP695.
    Peng Y; Hu Y; Xu S; Feng N; Wang L; Wang X
    Neurosci Lett; 2011 Jan; 487(2):211-6. PubMed ID: 20969923
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stimulation of non-amyloidogenic processing of amyloid-β protein precursor by cryptotanshinone involves activation and translocation of ADAM10 and PKC-α.
    Durairajan SS; Liu LF; Lu JH; Koo I; Maruyama K; Chung SK; Huang JD; Li M
    J Alzheimers Dis; 2011; 25(2):245-62. PubMed ID: 21403388
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cryptotanshinione upregulates alpha-secretase by activation PI3K pathway in cortical neurons.
    Mei Z; Situ B; Tan X; Zheng S; Zhang F; Yan P; Liu P
    Brain Res; 2010 Aug; 1348():165-73. PubMed ID: 20595051
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interleukin-1alpha stimulates non-amyloidogenic pathway by alpha-secretase (ADAM-10 and ADAM-17) cleavage of APP in human astrocytic cells involving p38 MAP kinase.
    Bandyopadhyay S; Hartley DM; Cahill CM; Lahiri DK; Chattopadhyay N; Rogers JT
    J Neurosci Res; 2006 Jul; 84(1):106-18. PubMed ID: 16724341
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.
    Meng P; Yoshida H; Matsumiya T; Imaizumi T; Tanji K; Xing F; Hayakari R; Dempoya J; Tatsuta T; Aizawa-Yashiro T; Mimura J; Kosaka K; Itoh K; Satoh K
    Neurosci Res; 2013 Feb; 75(2):94-102. PubMed ID: 23257508
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways.
    Webster NJ; Green KN; Settle VJ; Peers C; Vaughan PF
    Brain Res Mol Brain Res; 2004 Nov; 130(1-2):161-9. PubMed ID: 15519686
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of alpha-secretase and BACE-1 concurrently.
    Fu H; Dou J; Li W; Cui W; Mak S; Hu Q; Luo J; Lam CS; Pang Y; Youdim MB; Han Y
    Eur J Pharmacol; 2009 Nov; 623(1-3):14-21. PubMed ID: 19765582
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding.
    Parvathy S; Ehrlich M; Pedrini S; Diaz N; Refolo L; Buxbaum JD; Bogush A; Petanceska S; Gandy S
    J Neurochem; 2004 Aug; 90(4):1005-10. PubMed ID: 15287907
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Auraptene increases the production of amyloid-β via c-Jun N-terminal kinase-dependent activation of γ-secretase.
    Jung CG; Uhm KO; Horike H; Kim MJ; Misumi S; Ishida A; Ueda Y; Choi EK; Kim YS; Michikawa M; Hida H
    J Alzheimers Dis; 2015; 43(4):1215-28. PubMed ID: 25147119
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ERK1-independent α-secretase cut of β-amyloid precursor protein via M1 muscarinic receptors and PKCα/ε.
    Cisse M; Braun U; Leitges M; Fisher A; Pages G; Checler F; Vincent B
    Mol Cell Neurosci; 2011 Jul; 47(3):223-32. PubMed ID: 21570469
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
    Gandhi S; Refolo LM; Sambamurti K
    J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Involvement of M1-muscarinic acetylcholine receptors, protein kinase C and mitogen-activated protein kinase in the effect of huperzine A on secretory amyloid precursor protein-alpha.
    Yan H; Zhang HY; Tang XC
    Neuroreport; 2007 May; 18(7):689-92. PubMed ID: 17426600
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP.
    Corbett GT; Gonzalez FJ; Pahan K
    Proc Natl Acad Sci U S A; 2015 Jul; 112(27):8445-50. PubMed ID: 26080426
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.
    Panmanee J; Nopparat C; Chavanich N; Shukla M; Mukda S; Song W; Vincent B; Govitrapong P
    J Pineal Res; 2015 Oct; 59(3):308-20. PubMed ID: 26123100
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.
    Mei Z; Zhang F; Tao L; Zheng W; Cao Y; Wang Z; Tang S; Le K; Chen S; Pi R; Liu P
    Neurosci Lett; 2009 Mar; 452(2):90-5. PubMed ID: 19154776
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein.
    Harris B; Pereira I; Parkin E
    Brain Res; 2009 Nov; 1296():203-15. PubMed ID: 19679113
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The purinergic receptor P2X7 triggers alpha-secretase-dependent processing of the amyloid precursor protein.
    Delarasse C; Auger R; Gonnord P; Fontaine B; Kanellopoulos JM
    J Biol Chem; 2011 Jan; 286(4):2596-606. PubMed ID: 21081501
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of MAP kinase in the regulation of amyloid precursor protein processing by novel cholinesterase inhibitors derived from rasagiline.
    Yogev-Falach M; Amit T; Bar-Am O; Weinstock M; Youdim MB
    FASEB J; 2002 Oct; 16(12):1674-6. PubMed ID: 12206996
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 65.