BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 17949236)

  • 1. Down-regulation of vinculin upon MK886-induced apoptosis in LN18 glioblastoma cells.
    Magro AM; Magro AD; Cunningham C; Miller MR
    Neoplasma; 2007; 54(6):517-26. PubMed ID: 17949236
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP.
    Datta K; Biswal SS; Kehrer JP
    Biochem J; 1999 Jun; 340 ( Pt 2)(Pt 2):371-5. PubMed ID: 10333477
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A relationship between 5-lipoxygenase-activating protein and bcl-xL expression in murine pro-B lymphocytic FL5.12 cells.
    Datta K; Biswal SS; Xu J; Towndrow KM; Feng X; Kehrer JP
    J Biol Chem; 1998 Oct; 273(43):28163-9. PubMed ID: 9774436
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of peroxisome-proliferator-activated receptor (PPAR)alpha by MK886.
    Kehrer JP; Biswal SS; La E; Thuillier P; Datta K; Fischer SM; Vanden Heuvel JP
    Biochem J; 2001 Jun; 356(Pt 3):899-906. PubMed ID: 11389700
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metalloproteinase dependent reduction of cell surface cluster determinants upon the induction of apoptosis.
    Magro A; Magro A; Shrestha S; Brundage K; Rankin G
    Int J Oncol; 2014 May; 44(5):1539-50. PubMed ID: 24626736
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased expression of the lipocalin 24p3 as an apoptotic mechanism for MK886.
    Tong Z; Wu X; Kehrer JP
    Biochem J; 2003 May; 372(Pt 1):203-10. PubMed ID: 12614196
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fatty acid release and oxidation are factors in lipoxygenase inhibitor-induced apoptosis.
    La E; Kern JC; Atarod EB; Kehrer JP
    Toxicol Lett; 2003 Mar; 138(3):193-203. PubMed ID: 12565196
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Roles of 5-lipoxygenase activating protein in cell proliferation and apoptosis.
    Wu X; Biswal SS; Kehrer JP
    Cell Biol Toxicol; 2003 Jun; 19(3):135-43. PubMed ID: 12945742
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MK886-induced apoptosis depends on the 5-LO expression level in human malignant glioma cells.
    Lim JY; Oh JH; Jung JR; Kim SM; Ryu CH; Kim HT; Jeun SS
    J Neurooncol; 2010 May; 97(3):339-46. PubMed ID: 19862483
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proteolytic loss of bcl-x(L) in FL5.12 Cells undergoing apoptosis induced by MK886.
    Datta K; Kern JC; Biswal SS; Kehrer JP
    Toxicol Appl Pharmacol; 2001 Aug; 174(3):273-81. PubMed ID: 11485388
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of the 5-lipoxygenase activating protein inhibitor MK886 on voltage-gated and Ca2+-activated K+ currents in rat arterial myocytes.
    Smirnov SV; Knock GA; Aaronson PI
    Br J Pharmacol; 1998 Jun; 124(3):572-8. PubMed ID: 9647483
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanisms of N-acetylcysteine-driven enhancement of MK886-induced apoptosis.
    Deshpande VS; Kehrer JP
    Cell Biol Toxicol; 2006 Jul; 22(4):303-11. PubMed ID: 16817014
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ingenuity network-assisted transcription profiling: Identification of a new pharmacologic mechanism for MK886.
    Mayburd AL; Martlínez A; Sackett D; Liu H; Shih J; Tauler J; Avis I; Mulshine JL
    Clin Cancer Res; 2006 Mar; 12(6):1820-7. PubMed ID: 16551867
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 5-Lipoxygenase inhibitors reduce PC-3 cell proliferation and initiate nonnecrotic cell death.
    Anderson KM; Seed T; Vos M; Mulshine J; Meng J; Alrefai W; Ou D; Harris JE
    Prostate; 1998 Nov; 37(3):161-73. PubMed ID: 9792133
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Monocytic differentiation of leukemic HL-60 cells induced by co-treatment with TNF-alpha and MK886 requires activation of pro-apoptotic machinery.
    Procházková J; Stixová L; Soucek K; Hofmanová J; Kozubík A
    Eur J Haematol; 2009 Jul; 83(1):35-47. PubMed ID: 19220423
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lipoxygenase inhibitor MK886 potentiates TRAIL-induced apoptosis through CHOP- and p38 MAPK-mediated up-regulation of death receptor 5 in malignant glioma.
    Woo JS; Kim SM; Jeong CH; Ryu CH; Jeun SS
    Biochem Biophys Res Commun; 2013 Feb; 431(2):354-9. PubMed ID: 23261452
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Combination of all-trans retinoic acid and interferon-gamma upregulated p27(kip1) and down regulated CDK2 to cause cell cycle arrest leading to differentiation and apoptosis in human glioblastoma LN18 (PTEN-proficient) and U87MG (PTEN-deficient) cells.
    Zhang R; Banik NL; Ray SK
    Cancer Chemother Pharmacol; 2008 Aug; 62(3):407-16. PubMed ID: 17960384
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitors of the arachidonic acid pathway and peroxisome proliferator-activated receptor ligands have superadditive effects on lung cancer growth inhibition.
    Avis I; Martínez A; Tauler J; Zudaire E; Mayburd A; Abu-Ghazaleh R; Ondrey F; Mulshine JL
    Cancer Res; 2005 May; 65(10):4181-90. PubMed ID: 15899809
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Five-lipoxygenase inhibitors reduce Panc-1 survival: the mode of cell death and synergism of MK886 with gamma linolenic acid.
    Anderson KM; Seed T; Meng J; Ou D; Alrefai WA; Harris JE
    Anticancer Res; 1998; 18(2A):791-800. PubMed ID: 9615721
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An in vivo inhibitor of 5-lipoxygenase, MK886, at micromolar concentration induces apoptosis in U937 and CML cells.
    Anderson KM; Seed T; Jajeh A; Dudeja P; Byun T; Meng J; Ou D; Bonomi P; Harris JE
    Anticancer Res; 1996; 16(5A):2589-99. PubMed ID: 8917356
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.