These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1063 related articles for article (PubMed ID: 17950653)

  • 1. Achondroplasia: from genotype to phenotype.
    Richette P; Bardin T; Stheneur C
    Joint Bone Spine; 2008 Mar; 75(2):125-30. PubMed ID: 17950653
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fibroblast growth factor receptor-3 as a therapeutic target for Achondroplasia--genetic short limbed dwarfism.
    Aviezer D; Golembo M; Yayon A
    Curr Drug Targets; 2003 Jul; 4(5):353-65. PubMed ID: 12816345
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Achondroplasia: Current Options and Future Perspective.
    Bouali H; Latrech H
    Pediatr Endocrinol Rev; 2015 Jun; 12(4):388-95. PubMed ID: 26182483
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Delayed bone age due to a dual effect of FGFR3 mutation in Achondroplasia.
    Pannier S; Mugniery E; Jonquoy A; Benoist-Lasselin C; Odent T; Jais JP; Munnich A; Legeai-Mallet L
    Bone; 2010 Nov; 47(5):905-15. PubMed ID: 20673820
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype.
    Murakami S; Balmes G; McKinney S; Zhang Z; Givol D; de Crombrugghe B
    Genes Dev; 2004 Feb; 18(3):290-305. PubMed ID: 14871928
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Achondroplasia: Development, pathogenesis, and therapy.
    Ornitz DM; Legeai-Mallet L
    Dev Dyn; 2017 Apr; 246(4):291-309. PubMed ID: 27987249
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HDAC6 deficiency or inhibition blocks FGFR3 accumulation and improves bone growth in a model of achondroplasia.
    Ota S; Zhou ZQ; Romero MP; Yang G; Hurlin PJ
    Hum Mol Genet; 2016 Oct; 25(19):4227-4243. PubMed ID: 27506979
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FGFR3 induces degradation of BMP type I receptor to regulate skeletal development.
    Qi H; Jin M; Duan Y; Du X; Zhang Y; Ren F; Wang Y; Tian Q; Wang X; Wang Q; Zhu Y; Xie Y; Liu C; Cao X; Mishina Y; Chen D; Deng CX; Chang Z; Chen L
    Biochim Biophys Acta; 2014 Jul; 1843(7):1237-47. PubMed ID: 24657641
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Severe achondroplasia due to two de novo variants in the transmembrane domain of FGFR3 on the same allele: A case report.
    Nagata T; Matsushita M; Mishima K; Kamiya Y; Kato K; Toyama M; Ogi T; Ishiguro N; Kitoh H
    Mol Genet Genomic Med; 2020 Mar; 8(3):e1148. PubMed ID: 31975530
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations of the fibroblast growth factor receptor-3 gene in achondroplasia.
    Rousseau F; Bonaventure J; Legeai-Mallet L; Pelet A; Rozet JM; Maroteaux P; Le Merrer M; Munnich A
    Horm Res; 1996; 45(1-2):108-10. PubMed ID: 8742128
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.
    Colvin JS; Bohne BA; Harding GW; McEwen DG; Ornitz DM
    Nat Genet; 1996 Apr; 12(4):390-7. PubMed ID: 8630492
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia.
    Lee YC; Song IW; Pai YJ; Chen SD; Chen YT
    Sci Rep; 2017 Feb; 7():43220. PubMed ID: 28230213
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis.
    Chen L; Adar R; Yang X; Monsonego EO; Li C; Hauschka PV; Yayon A; Deng CX
    J Clin Invest; 1999 Dec; 104(11):1517-25. PubMed ID: 10587515
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
    Martin L; Kaci N; Estibals V; Goudin N; Garfa-Traore M; Benoist-Lasselin C; Dambroise E; Legeai-Mallet L
    Hum Mol Genet; 2018 Jan; 27(1):1-13. PubMed ID: 29040558
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Meckel's and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible.
    Biosse Duplan M; Komla-Ebri D; Heuzé Y; Estibals V; Gaudas E; Kaci N; Benoist-Lasselin C; Zerah M; Kramer I; Kneissel M; Porta DG; Di Rocco F; Legeai-Mallet L
    Hum Mol Genet; 2016 Jul; 25(14):2997-3010. PubMed ID: 27260401
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia.
    Rousseau F; Bonaventure J; Legeai-Mallet L; Pelet A; Rozet JM; Maroteaux P; Le Merrer M; Munnich A
    Nature; 1994 Sep; 371(6494):252-4. PubMed ID: 8078586
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Achondroplasia: A form of disproportionate dwarfism - A case report.
    Swathi KV; Maragathavalli G
    Indian J Dent Res; 2020; 31(5):794-798. PubMed ID: 33433522
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Ser(365)-->Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia.
    Chen L; Li C; Qiao W; Xu X; Deng C
    Hum Mol Genet; 2001 Mar; 10(5):457-65. PubMed ID: 11181569
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors.
    Li C; Chen L; Iwata T; Kitagawa M; Fu XY; Deng CX
    Hum Mol Genet; 1999 Jan; 8(1):35-44. PubMed ID: 9887329
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Highly activated Fgfr3 with the K644M mutation causes prolonged survival in severe dwarf mice.
    Iwata T; Li CL; Deng CX; Francomano CA
    Hum Mol Genet; 2001 Jun; 10(12):1255-64. PubMed ID: 11406607
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 54.