BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

58 related articles for article (PubMed ID: 17951244)

  • 1. SmgGDS regulates cell proliferation, migration, and NF-kappaB transcriptional activity in non-small cell lung carcinoma.
    Tew GW; Lorimer EL; Berg TJ; Zhi H; Li R; Williams CL
    J Biol Chem; 2008 Jan; 283(2):963-76. PubMed ID: 17951244
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding.
    Shimizu H; Toma-Fukai S; Saijo S; Shimizu N; Kontani K; Katada T; Shimizu T
    J Biol Chem; 2017 Aug; 292(32):13441-13448. PubMed ID: 28630045
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The chaperone protein SmgGDS interacts with small GTPases entering the prenylation pathway by recognizing the last amino acid in the CAAX motif.
    Schuld NJ; Vervacke JS; Lorimer EL; Simon NC; Hauser AD; Barbieri JT; Distefano MD; Williams CL
    J Biol Chem; 2014 Mar; 289(10):6862-6876. PubMed ID: 24415755
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS.
    Koehn OJ; Lorimer E; Unger B; Harris R; Das AS; Suazo KF; Auger SA; Distefano MD; Prokop JW; Williams CL
    J Biol Chem; 2023 Jun; 299(6):104698. PubMed ID: 37059183
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Splice variants of SmgGDS control small GTPase prenylation and membrane localization.
    Berg TJ; Gastonguay AJ; Lorimer EL; Kuhnmuench JR; Li R; Fields AP; Williams CL
    J Biol Chem; 2010 Nov; 285(46):35255-66. PubMed ID: 20709748
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers.
    Schuld NJ; Hauser AD; Gastonguay AJ; Wilson JM; Lorimer EL; Williams CL
    Cell Cycle; 2014; 13(6):941-52. PubMed ID: 24552806
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The SmgGDS splice variant SmgGDS-558 is a key promoter of tumor growth and RhoA signaling in breast cancer.
    Hauser AD; Bergom C; Schuld NJ; Chen X; Lorimer EL; Huang J; Mackinnon AC; Williams CL
    Mol Cancer Res; 2014 Jan; 12(1):130-42. PubMed ID: 24197117
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering.
    Ntantie E; Gonyo P; Lorimer EL; Hauser AD; Schuld N; McAllister D; Kalyanaraman B; Dwinell MB; Auchampach JA; Williams CL
    Sci Signal; 2013 May; 6(277):ra39. PubMed ID: 23716716
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cell competition and cancer from Drosophila to mammals.
    Cong B; Cagan RL
    Oncogenesis; 2024 Jan; 13(1):1. PubMed ID: 38172609
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural and biophysical properties of farnesylated KRas interacting with the chaperone SmgGDS-558.
    Michalak DJ; Unger B; Lorimer E; Grishaev A; Williams CL; Heinrich F; Lösche M
    Biophys J; 2022 Oct; 121(19):3684-3697. PubMed ID: 35614853
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Review: Mechanism of
    Saahene RO; Agbo E; Barnes P; Yahaya ES; Amoani B; Nuvor SV; Okyere P
    Evid Based Complement Alternat Med; 2021; 2021():4514342. PubMed ID: 34484390
    [No Abstract]   [Full Text] [Related]  

  • 12. SmgGDS: An Emerging Master Regulator of Prenylation and Trafficking by Small GTPases in the Ras and Rho Families.
    Brandt AC; Koehn OJ; Williams CL
    Front Mol Biosci; 2021; 8():685135. PubMed ID: 34222337
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HMGB1 enhances chemotherapy resistance in multiple myeloma cells by activating the nuclear factor-κB pathway.
    Ning J; Yang R; Wang H; Cui L
    Exp Ther Med; 2021 Jul; 22(1):705. PubMed ID: 34007314
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FSTL1 increases cisplatin sensitivity in epithelial ovarian cancer cells by inhibition of NF-κB pathway.
    Liu YK; Jia YJ; Liu SH; Ma J
    Cancer Chemother Pharmacol; 2021 Mar; 87(3):405-414. PubMed ID: 33392640
    [TBL] [Abstract][Full Text] [Related]  

  • 15. K-Ras prenylation as a potential anticancer target.
    Baranyi M; Buday L; Hegedűs B
    Cancer Metastasis Rev; 2020 Dec; 39(4):1127-1141. PubMed ID: 32524209
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutated RAP1GDS1 causes a new syndrome of dysmorphic feature, intellectual disability & speech delay.
    Asiri A; Aloyouni E; Umair M; Alyafee Y; Al Tuwaijri A; Alhamoudi KM; Almuzzaini B; Al Baz A; Alwadaani D; Nashabat M; Alfadhel M
    Ann Clin Transl Neurol; 2020 Jun; 7(6):956-964. PubMed ID: 32431071
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Splice switching an oncogenic ratio of SmgGDS isoforms as a strategy to diminish malignancy.
    Brandt AC; McNally L; Lorimer EL; Unger B; Koehn OJ; Suazo KF; Rein L; Szabo A; Tsaih SW; Distefano MD; Flister MJ; Rigo F; McNally MT; Williams CL
    Proc Natl Acad Sci U S A; 2020 Feb; 117(7):3627-3636. PubMed ID: 32019878
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural Insights into the Regulation Mechanism of Small GTPases by GEFs.
    Toma-Fukai S; Shimizu T
    Molecules; 2019 Sep; 24(18):. PubMed ID: 31514408
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism.
    Shimizu H; Toma-Fukai S; Kontani K; Katada T; Shimizu T
    Proc Natl Acad Sci U S A; 2018 Sep; 115(38):9563-9568. PubMed ID: 30190425
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression.
    Gonyo P; Bergom C; Brandt AC; Tsaih SW; Sun Y; Bigley TM; Lorimer EL; Terhune SS; Rui H; Flister MJ; Long RM; Williams CL
    Oncogene; 2017 Dec; 36(50):6873-6883. PubMed ID: 28806394
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 3.