BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

290 related articles for article (PubMed ID: 17951578)

  • 1. Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases.
    Smith BC; Denu JM
    J Biol Chem; 2007 Dec; 282(51):37256-65. PubMed ID: 17951578
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide.
    Smith BC; Denu JM
    Biochemistry; 2007 Dec; 46(50):14478-86. PubMed ID: 18027980
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases.
    Borra MT; Langer MR; Slama JT; Denu JM
    Biochemistry; 2004 Aug; 43(30):9877-87. PubMed ID: 15274642
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Use of substrate analogs and mutagenesis to study substrate binding and catalysis in the Sir2 family of NAD-dependent protein deacetylases.
    Khan AN; Lewis PN
    J Biol Chem; 2006 Apr; 281(17):11702-11. PubMed ID: 16520376
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
    Zhao K; Harshaw R; Chai X; Marmorstein R
    Proc Natl Acad Sci U S A; 2004 Jun; 101(23):8563-8. PubMed ID: 15150415
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SIR2: the biochemical mechanism of NAD(+)-dependent protein deacetylation and ADP-ribosyl enzyme intermediates.
    Sauve AA; Schramm VL
    Curr Med Chem; 2004 Apr; 11(7):807-26. PubMed ID: 15078167
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sirtuin mechanism and inhibition: explored with N(ε)-acetyl-lysine analogs.
    Hirsch BM; Zheng W
    Mol Biosyst; 2011 Jan; 7(1):16-28. PubMed ID: 20842312
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Function and metabolism of sirtuin metabolite O-acetyl-ADP-ribose.
    Tong L; Denu JM
    Biochim Biophys Acta; 2010 Aug; 1804(8):1617-25. PubMed ID: 20176146
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine.
    Smith BC; Denu JM
    Biochemistry; 2006 Jan; 45(1):272-82. PubMed ID: 16388603
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nepsilon-thioacetyl-lysine: a multi-facet functional probe for enzymatic protein lysine Nepsilon-deacetylation.
    Fatkins DG; Monnot AD; Zheng W
    Bioorg Med Chem Lett; 2006 Jul; 16(14):3651-6. PubMed ID: 16697640
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases.
    Jackson MD; Schmidt MT; Oppenheimer NJ; Denu JM
    J Biol Chem; 2003 Dec; 278(51):50985-98. PubMed ID: 14522996
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH.
    Madsen AS; Andersen C; Daoud M; Anderson KA; Laursen JS; Chakladar S; Huynh FK; Colaço AR; Backos DS; Fristrup P; Hirschey MD; Olsen CA
    J Biol Chem; 2016 Mar; 291(13):7128-41. PubMed ID: 26861872
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-lysine propionylation controls the activity of propionyl-CoA synthetase.
    Garrity J; Gardner JG; Hawse W; Wolberger C; Escalante-Semerena JC
    J Biol Chem; 2007 Oct; 282(41):30239-45. PubMed ID: 17684016
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide.
    Zhao K; Chai X; Marmorstein R
    Structure; 2003 Nov; 11(11):1403-11. PubMed ID: 14604530
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of NAD+ dependent histone deacetylases (sirtuins) in ageing.
    Trapp J; Jung M
    Curr Drug Targets; 2006 Nov; 7(11):1553-60. PubMed ID: 17100594
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N(epsilon)-Modified lysine containing inhibitors for SIRT1 and SIRT2.
    Huhtiniemi T; Suuronen T; Lahtela-Kakkonen M; Bruijn T; Jääskeläinen S; Poso A; Salminen A; Leppänen J; Jarho E
    Bioorg Med Chem; 2010 Aug; 18(15):5616-25. PubMed ID: 20630764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Azalysine analogues as probes for protein lysine deacetylation and demethylation.
    Dancy BC; Ming SA; Papazyan R; Jelinek CA; Majumdar A; Sun Y; Dancy BM; Drury WJ; Cotter RJ; Taverna SD; Cole PA
    J Am Chem Soc; 2012 Mar; 134(11):5138-48. PubMed ID: 22352831
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation.
    Liou GG; Tanny JC; Kruger RG; Walz T; Moazed D
    Cell; 2005 May; 121(4):515-527. PubMed ID: 15907466
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hydrolysis of O-acetyl-ADP-ribose isomers by ADP-ribosylhydrolase 3.
    Kasamatsu A; Nakao M; Smith BC; Comstock LR; Ono T; Kato J; Denu JM; Moss J
    J Biol Chem; 2011 Jun; 286(24):21110-7. PubMed ID: 21498885
    [TBL] [Abstract][Full Text] [Related]  

  • 20. One-step, nonenzymatic synthesis of O-acetyl-ADP-ribose and analogues from NAD and carboxylates.
    Szczepankiewicz BG; Koppetsch KJ; Perni RB
    J Org Chem; 2011 Aug; 76(16):6465-74. PubMed ID: 21639110
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.