225 related articles for article (PubMed ID: 17956260)
1. Solid-state NMR spectroscopy as a tool for drug design: from membrane-embedded targets to amyloid fibrils.
Middleton DA
Biochem Soc Trans; 2007 Nov; 35(Pt 5):985-90. PubMed ID: 17956260
[TBL] [Abstract][Full Text] [Related]
2. NMR techniques for characterization of ligand binding: utility for lead generation and optimization in drug discovery.
Moore JM
Biopolymers; 1999; 51(3):221-43. PubMed ID: 10516573
[TBL] [Abstract][Full Text] [Related]
3. Fragment-based screening using X-ray crystallography and NMR spectroscopy.
Jhoti H; Cleasby A; Verdonk M; Williams G
Curr Opin Chem Biol; 2007 Oct; 11(5):485-93. PubMed ID: 17851109
[TBL] [Abstract][Full Text] [Related]
4. Structure-based development of target-specific compound libraries.
Orry AJ; Abagyan RA; Cavasotto CN
Drug Discov Today; 2006 Mar; 11(5-6):261-6. PubMed ID: 16580603
[TBL] [Abstract][Full Text] [Related]
5. High-throughput X-ray crystallography for drug discovery.
Blundell TL; Patel S
Curr Opin Pharmacol; 2004 Oct; 4(5):490-6. PubMed ID: 15351354
[TBL] [Abstract][Full Text] [Related]
6. Crystallography, NMR and virtual screening: integrated tools for drug discovery.
Muchmore SW; Hajduk PJ
Curr Opin Drug Discov Devel; 2003 Jul; 6(4):544-9. PubMed ID: 12951817
[TBL] [Abstract][Full Text] [Related]
7. Design, selection, and characterization of thioflavin-based intercalation compounds with metal chelating properties for application in Alzheimer's disease.
Rodríguez-Rodríguez C; Sánchez de Groot N; Rimola A; Alvarez-Larena A; Lloveras V; Vidal-Gancedo J; Ventura S; Vendrell J; Sodupe M; González-Duarte P
J Am Chem Soc; 2009 Feb; 131(4):1436-51. PubMed ID: 19133767
[TBL] [Abstract][Full Text] [Related]
8. Use of 19F NMR spectroscopy to screen chemical libraries for ligands that bind to proteins.
Tengel T; Fex T; Emtenas H; Almqvist F; Sethson I; Kihlberg J
Org Biomol Chem; 2004 Mar; 2(5):725-31. PubMed ID: 14985813
[TBL] [Abstract][Full Text] [Related]
9. Using NMR for ligand discovery and optimization.
Villar HO; Yan J; Hansen MR
Curr Opin Chem Biol; 2004 Aug; 8(4):387-91. PubMed ID: 15288248
[TBL] [Abstract][Full Text] [Related]
10. A structure-based strategy to identify new molecular scaffolds targeting the bacterial ribosomal A-site.
Foloppe N; Chen IJ; Davis B; Hold A; Morley D; Howes R
Bioorg Med Chem; 2004 Mar; 12(5):935-47. PubMed ID: 14980606
[TBL] [Abstract][Full Text] [Related]
11. Application of solid-state 35Cl NMR to the structural characterization of hydrochloride pharmaceuticals and their polymorphs.
Hamaed H; Pawlowski JM; Cooper BF; Fu R; Eichhorn SH; Schurko RW
J Am Chem Soc; 2008 Aug; 130(33):11056-65. PubMed ID: 18656917
[TBL] [Abstract][Full Text] [Related]
12. Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based design.
Tsao DH; Sutherland AG; Jennings LD; Li Y; Rush TS; Alvarez JC; Ding W; Dushin EG; Dushin RG; Haney SA; Kenny CH; Malakian AK; Nilakantan R; Mosyak L
Bioorg Med Chem; 2006 Dec; 14(23):7953-61. PubMed ID: 16919463
[TBL] [Abstract][Full Text] [Related]
13. Recent advances in solid-state NMR spectroscopy of spin I=1/2 nuclei.
Lesage A
Phys Chem Chem Phys; 2009 Aug; 11(32):6876-91. PubMed ID: 19652822
[TBL] [Abstract][Full Text] [Related]
14. Solid-state NMR spectroscopy on complex biomolecules.
Renault M; Cukkemane A; Baldus M
Angew Chem Int Ed Engl; 2010 Nov; 49(45):8346-57. PubMed ID: 20941715
[TBL] [Abstract][Full Text] [Related]
15. Competition STD NMR for the detection of high-affinity ligands and NMR-based screening.
Wang YS; Liu D; Wyss DF
Magn Reson Chem; 2004 Jun; 42(6):485-9. PubMed ID: 15137040
[TBL] [Abstract][Full Text] [Related]
16. Molecular interactions investigated by multi-dimensional solid-state NMR.
Baldus M
Curr Opin Struct Biol; 2006 Oct; 16(5):618-23. PubMed ID: 16942870
[TBL] [Abstract][Full Text] [Related]
17. From virtuality to reality - Virtual screening in lead discovery and lead optimization: a medicinal chemistry perspective.
Rester U
Curr Opin Drug Discov Devel; 2008 Jul; 11(4):559-68. PubMed ID: 18600572
[TBL] [Abstract][Full Text] [Related]
18. Evaluation of solid state form of troglitazone by solid state NMR spectroscopy.
Suzuki N; Kawasaki T
J Pharm Biomed Anal; 2005 Feb; 37(1):177-81. PubMed ID: 15664759
[TBL] [Abstract][Full Text] [Related]
19. Novel prostaglandin D synthase inhibitors generated by fragment-based drug design.
Hohwy M; Spadola L; Lundquist B; Hawtin P; Dahmén J; Groth-Clausen I; Nilsson E; Persdotter S; von Wachenfeldt K; Folmer RH; Edman K
J Med Chem; 2008 Apr; 51(7):2178-86. PubMed ID: 18341273
[TBL] [Abstract][Full Text] [Related]
20. Fragment-based lead discovery: a chemical update.
Erlanson DA
Curr Opin Biotechnol; 2006 Dec; 17(6):643-52. PubMed ID: 17084612
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]