These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 17956719)

  • 1. Presenilin: running with scissors in the membrane.
    Selkoe DJ; Wolfe MS
    Cell; 2007 Oct; 131(2):215-21. PubMed ID: 17956719
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Assembly of the presenilin γ-/ε-secretase complex.
    St George-Hyslop P; Fraser PE
    J Neurochem; 2012 Jan; 120 Suppl 1():84-88. PubMed ID: 22122073
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alzheimer's disease sends the wrong signals--a perspective.
    Neve RL
    Amyloid; 2008 Mar; 15(1):1-4. PubMed ID: 18266116
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Assembly and activation of the gamma-secretase complex: roles of presenilin cofactors.
    Iwatsubo T
    Mol Psychiatry; 2004 Jan; 9(1):8-10. PubMed ID: 14581930
    [No Abstract]   [Full Text] [Related]  

  • 5. Molecular models of the interface between anterior pharynx-defective protein 1 (APH-1) and presenilin involving GxxxG motifs.
    Jozwiak K; Krzysko KA; Bojarski L; Gacia M; Filipek S
    ChemMedChem; 2008 Apr; 3(4):627-34. PubMed ID: 18061918
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An alternative spliced mouse presenilin-2 mRNA encodes a novel gamma-secretase inhibitor.
    Suzuki Y; Ohta K; Itoh M; Sakoh-Sumitomo Y; Mitsuda T; Ueda M; Hayakawa-Yano Y; Li S; Hida Y; Inuzuka T; Jung YK; Nakagawa T
    FEBS Lett; 2009 May; 583(9):1403-8. PubMed ID: 19376115
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gamma-secretase and the intramembrane proteolysis of Notch.
    Jorissen E; De Strooper B
    Curr Top Dev Biol; 2010; 92():201-30. PubMed ID: 20816396
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Familial Alzheimer's disease presenilin 1 mutation M146V increases gamma secretase cutting of p75NTR in vitro.
    Hatchett CS; Tyler S; Armstrong D; Dawbarn D; Allen SJ
    Brain Res; 2007 May; 1147():248-55. PubMed ID: 17349981
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Presenilin diversifies its portfolio.
    Parks AL; Curtis D
    Trends Genet; 2007 Mar; 23(3):140-50. PubMed ID: 17280736
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Biology and pathobiology of the intramembrane proteolysis by gamma-secretase].
    Tomita T
    Tanpakushitsu Kakusan Koso; 2009 Oct; 54(13):1747-53. PubMed ID: 19827607
    [No Abstract]   [Full Text] [Related]  

  • 11. Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 gamma-secretase complexes.
    Placanica L; Tarassishin L; Yang G; Peethumnongsin E; Kim SH; Zheng H; Sisodia SS; Li YM
    J Biol Chem; 2009 Jan; 284(5):2967-2977. PubMed ID: 19036728
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Structure and function analysis of gamma-secretase complex toward development of therapeutics for Alzheimer's disease].
    Tomita T
    Tanpakushitsu Kakusan Koso; 2009 Sep; 54(12 Suppl):1684-9. PubMed ID: 21089607
    [No Abstract]   [Full Text] [Related]  

  • 13. The gamma-secretase complex: membrane-embedded proteolytic ensemble.
    Wolfe MS
    Biochemistry; 2006 Jul; 45(26):7931-9. PubMed ID: 16800619
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of sulindac sulfide on the membrane architecture and the activity of gamma-secretase.
    Gamerdinger M; Clement AB; Behl C
    Neuropharmacology; 2008 May; 54(6):998-1005. PubMed ID: 18359496
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rac1 changes the substrate specificity of gamma-secretase between amyloid precursor protein and Notch1.
    Boo JH; Sohn JH; Kim JE; Song H; Mook-Jung I
    Biochem Biophys Res Commun; 2008 Aug; 372(4):913-7. PubMed ID: 18538664
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Secretase inhibitors and modulators for Alzheimer's disease treatment.
    Tomita T
    Expert Rev Neurother; 2009 May; 9(5):661-79. PubMed ID: 19402777
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.
    Martone RL; Zhou H; Atchison K; Comery T; Xu JZ; Huang X; Gong X; Jin M; Kreft A; Harrison B; Mayer SC; Aschmies S; Gonzales C; Zaleska MM; Riddell DR; Wagner E; Lu P; Sun SC; Sonnenberg-Reines J; Oganesian A; Adkins K; Leach MW; Clarke DW; Huryn D; Abou-Gharbia M; Magolda R; Bard J; Frick G; Raje S; Forlow SB; Balliet C; Burczynski ME; Reinhart PH; Wan HI; Pangalos MN; Jacobsen JS
    J Pharmacol Exp Ther; 2009 Nov; 331(2):598-608. PubMed ID: 19671883
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
    Sevalle J; Ayral E; Hernandez JF; Martinez J; Checler F
    J Neurochem; 2009 Jul; 110(1):275-83. PubMed ID: 19457123
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Increased expression of the gamma-secretase components presenilin-1 and nicastrin in activated astrocytes and microglia following traumatic brain injury.
    Nadler Y; Alexandrovich A; Grigoriadis N; Hartmann T; Rao KS; Shohami E; Stein R
    Glia; 2008 Apr; 56(5):552-67. PubMed ID: 18240300
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a γ-secretase-independent manner.
    Neely KM; Green KN; LaFerla FM
    J Neurosci; 2011 Feb; 31(8):2781-91. PubMed ID: 21414900
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.