BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

362 related articles for article (PubMed ID: 17960137)

  • 1. Hedgehog regulates smoothened activity by inducing a conformational switch.
    Zhao Y; Tong C; Jiang J
    Nature; 2007 Nov; 450(7167):252-8. PubMed ID: 17960137
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transducing the Hedgehog signal across the plasma membrane.
    Zhao Y; Tong C; Jiang J
    Fly (Austin); 2007; 1(6):333-6. PubMed ID: 18820483
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner.
    Fan J; Liu Y; Jia J
    Dev Biol; 2012 Jun; 366(2):172-84. PubMed ID: 22537496
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation.
    Shi Q; Li S; Jia J; Jiang J
    Development; 2011 Oct; 138(19):4219-31. PubMed ID: 21852395
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Smoothened oligomerization/higher order clustering in lipid rafts is essential for high Hedgehog activity transduction.
    Shi D; Lv X; Zhang Z; Yang X; Zhou Z; Zhang L; Zhao Y
    J Biol Chem; 2013 May; 288(18):12605-14. PubMed ID: 23532857
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation.
    Carroll CE; Marada S; Stewart DP; Ouyang JX; Ogden SK
    Development; 2012 Feb; 139(3):612-21. PubMed ID: 22223683
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail.
    Jiang K; Liu Y; Fan J; Zhang J; Li XA; Evers BM; Zhu H; Jia J
    PLoS Biol; 2016 Feb; 14(2):e1002375. PubMed ID: 26863604
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase.
    Li S; Li S; Han Y; Tong C; Wang B; Chen Y; Jiang J
    PLoS Biol; 2016 Jun; 14(6):e1002481. PubMed ID: 27280464
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila.
    Nakano Y; Nystedt S; Shivdasani AA; Strutt H; Thomas C; Ingham PW
    Mech Dev; 2004 Jun; 121(6):507-18. PubMed ID: 15172682
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Drosophila Vps36 regulates Smo trafficking in Hedgehog signaling.
    Yang X; Mao F; Lv X; Zhang Z; Fu L; Lu Y; Wu W; Zhou Z; Zhang L; Zhao Y
    J Cell Sci; 2013 Sep; 126(Pt 18):4230-8. PubMed ID: 23843610
    [TBL] [Abstract][Full Text] [Related]  

  • 11. G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling.
    Ogden SK; Fei DL; Schilling NS; Ahmed YF; Hwa J; Robbins DJ
    Nature; 2008 Dec; 456(7224):967-70. PubMed ID: 18987629
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation.
    Liu Y; Cao X; Jiang J; Jia J
    Genes Dev; 2007 Aug; 21(15):1949-63. PubMed ID: 17671093
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation.
    Li S; Ma G; Wang B; Jiang J
    Sci Signal; 2014 Jul; 7(332):ra62. PubMed ID: 24985345
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dose-dependent transduction of Hedgehog relies on phosphorylation-based feedback between the G-protein-coupled receptor Smoothened and the kinase Fused.
    Sanial M; Bécam I; Hofmann L; Behague J; Argüelles C; Gourhand V; Bruzzone L; Holmgren RA; Plessis A
    Development; 2017 May; 144(10):1841-1850. PubMed ID: 28360132
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sequential phosphorylation of smoothened transduces graded hedgehog signaling.
    Su Y; Ospina JK; Zhang J; Michelson AP; Schoen AM; Zhu AJ
    Sci Signal; 2011 Jul; 4(180):ra43. PubMed ID: 21730325
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hedgehog-regulated atypical PKC promotes phosphorylation and activation of Smoothened and Cubitus interruptus in Drosophila.
    Jiang K; Liu Y; Fan J; Epperly G; Gao T; Jiang J; Jia J
    Proc Natl Acad Sci U S A; 2014 Nov; 111(45):E4842-50. PubMed ID: 25349414
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transduction of the Hedgehog signal through the dimerization of Fused and the nuclear translocation of Cubitus interruptus.
    Zhang Y; Mao F; Lu Y; Wu W; Zhang L; Zhao Y
    Cell Res; 2011 Oct; 21(10):1436-51. PubMed ID: 21844892
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2.
    Yang C; Chen W; Chen Y; Jiang J
    Cell Res; 2012 Nov; 22(11):1593-604. PubMed ID: 22986504
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidence for a novel feedback loop in the Hedgehog pathway involving Smoothened and Fused.
    Claret S; Sanial M; Plessis A
    Curr Biol; 2007 Aug; 17(15):1326-33. PubMed ID: 17658259
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A broadly conserved g-protein-coupled receptor kinase phosphorylation mechanism controls Drosophila smoothened activity.
    Maier D; Cheng S; Faubert D; Hipfner DR
    PLoS Genet; 2014 Jul; 10(7):e1004399. PubMed ID: 25009998
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.