BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 17960358)

  • 1. Fuel-induced amplification of insulin secretion in mouse pancreatic islets exposed to a high sulfonylurea concentration: role of the NADPH/NADP+ ratio.
    Panten U; Rustenbeck I
    Diabetologia; 2008 Jan; 51(1):101-9. PubMed ID: 17960358
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective loss of glucose-induced amplification of insulin secretion in mouse pancreatic islets pretreated with sulfonylurea in the absence of fuels.
    Urban KA; Panten U
    Diabetologia; 2005 Dec; 48(12):2563-6. PubMed ID: 16283243
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acute metabolic amplification of insulin secretion in mouse islets is mediated by mitochondrial export of metabolites, but not by mitochondrial energy generation.
    Panten U; Willenborg M; Schumacher K; Hamada A; Ghaly H; Rustenbeck I
    Metabolism; 2013 Oct; 62(10):1375-86. PubMed ID: 23790612
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Triggering and amplification of insulin secretion by dimethyl alpha-ketoglutarate, a membrane permeable alpha-ketoglutarate analogue.
    Willenborg M; Panten U; Rustenbeck I
    Eur J Pharmacol; 2009 Apr; 607(1-3):41-6. PubMed ID: 19233162
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acute metabolic amplification of insulin secretion in mouse islets: Role of cytosolic acetyl-CoA.
    Panten U; Früh E; Reckers K; Rustenbeck I
    Metabolism; 2016 Sep; 65(9):1225-9. PubMed ID: 27506729
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic amplification of insulin secretion is differentially desensitized by depolarization in the absence of exogenous fuels.
    Schulze T; Morsi M; Reckers K; Brüning D; Seemann N; Panten U; Rustenbeck I
    Metabolism; 2017 Feb; 67():1-13. PubMed ID: 28081772
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of insulin secretion in mouse islets: metabolic amplification by alpha-ketoisocaproate coincides with rapid and sustained increase in acetyl-CoA content.
    Panten U; Brüning D; Rustenbeck I
    Naunyn Schmiedebergs Arch Pharmacol; 2023 Feb; 396(2):353-364. PubMed ID: 36355207
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucose both inhibits and stimulates insulin secretion from isolated pancreatic islets exposed to maximally effective concentrations of sulfonylureas.
    Panten U; Schwanstecher M; Wallasch A; Lenzen S
    Naunyn Schmiedebergs Arch Pharmacol; 1988 Oct; 338(4):459-62. PubMed ID: 3149719
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells.
    Nenquin M; Szollosi A; Aguilar-Bryan L; Bryan J; Henquin JC
    J Biol Chem; 2004 Jul; 279(31):32316-24. PubMed ID: 15175349
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytosolic ratios of free [NADPH]/[NADP+] and [NADH]/[NAD+] in mouse pancreatic islets, and nutrient-induced insulin secretion.
    Hedeskov CJ; Capito K; Thams P
    Biochem J; 1987 Jan; 241(1):161-7. PubMed ID: 3551925
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glucose regulation of insulin secretion independent of the opening or closure of adenosine triphosphate-sensitive K+ channels in beta cells.
    Sato Y; Anello M; Henquin JC
    Endocrinology; 1999 May; 140(5):2252-7. PubMed ID: 10218978
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sulphonylureas do not increase insulin secretion by a mechanism other than a rise in cytoplasmic Ca2+ in pancreatic B-cells.
    Garcia-Barrado MJ; Jonas JC; Gilon P; Henquin JC
    Eur J Pharmacol; 1996 Mar; 298(3):279-86. PubMed ID: 8846827
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transamination is required for {alpha}-ketoisocaproate but not leucine to stimulate insulin secretion.
    Zhou Y; Jetton TL; Goshorn S; Lynch CJ; She P
    J Biol Chem; 2010 Oct; 285(44):33718-26. PubMed ID: 20736162
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin stimulus-secretion coupling is triggered by a novel thiazolidinedione/sulfonylurea hybrid in rat pancreatic islets.
    Mendes CP; Postal BG; Oliveira GTC; Castro AJG; Frederico MJS; Moraes ALL; Neuenfeldt PD; Nunes RJ; Menegaz D; Silva FRMB
    J Cell Physiol; 2018 Jan; 234(1):509-520. PubMed ID: 29968920
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism of the insulin-releasing action of alpha-ketoisocaproate and related alpha-keto acid anions.
    Heissig H; Urban KA; Hastedt K; Zünkler BJ; Panten U
    Mol Pharmacol; 2005 Oct; 68(4):1097-105. PubMed ID: 16014804
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BLX-1002, a novel thiazolidinedione with no PPAR affinity, stimulates AMP-activated protein kinase activity, raises cytosolic Ca2+, and enhances glucose-stimulated insulin secretion in a PI3K-dependent manner.
    Zhang F; Dey D; Bränström R; Forsberg L; Lu M; Zhang Q; Sjöholm A
    Am J Physiol Cell Physiol; 2009 Feb; 296(2):C346-54. PubMed ID: 19052259
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glucose triggers protein kinase A-dependent insulin secretion in mouse pancreatic islets through activation of the K+ATP channel-dependent pathway.
    Thams P; Anwar MR; Capito K
    Eur J Endocrinol; 2005 Apr; 152(4):671-7. PubMed ID: 15817925
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alterations of insulin secretion from mouse islets treated with sulphonylureas: perturbations of Ca2+ regulation prevail over changes in insulin content.
    Anello M; Gilon P; Henquin JC
    Br J Pharmacol; 1999 Aug; 127(8):1883-91. PubMed ID: 10482920
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal.
    Szollosi A; Nenquin M; Henquin JC
    J Biol Chem; 2007 May; 282(20):14768-76. PubMed ID: 17389589
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.
    Odegaard ML; Joseph JW; Jensen MV; Lu D; Ilkayeva O; Ronnebaum SM; Becker TC; Newgard CB
    J Biol Chem; 2010 May; 285(22):16530-7. PubMed ID: 20356834
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.