These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

371 related articles for article (PubMed ID: 17963372)

  • 1. Design, synthesis, and characterization of new iron chelators with anti-proliferative activity: structure-activity relationships of novel thiohydrazone analogues.
    Kalinowski DS; Sharpe PC; Bernhardt PV; Richardson DR
    J Med Chem; 2007 Nov; 50(24):6212-25. PubMed ID: 17963372
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.
    Kalinowski DS; Yu Y; Sharpe PC; Islam M; Liao YT; Lovejoy DB; Kumar N; Bernhardt PV; Richardson DR
    J Med Chem; 2007 Jul; 50(15):3716-29. PubMed ID: 17602603
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-activity relationships of novel iron chelators for the treatment of iron overload disease: the methyl pyrazinylketone isonicotinoyl hydrazone series.
    Kalinowski DS; Sharpe PC; Bernhardt PV; Richardson DR
    J Med Chem; 2008 Jan; 51(2):331-44. PubMed ID: 18159922
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: redox activity, iron complexation and characterization of their antitumor activity.
    Richardson DR; Kalinowski DS; Richardson V; Sharpe PC; Lovejoy DB; Islam M; Bernhardt PV
    J Med Chem; 2009 Mar; 52(5):1459-70. PubMed ID: 19216562
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alkyl substituted 2'-benzoylpyridine thiosemicarbazone chelators with potent and selective anti-neoplastic activity: novel ligands that limit methemoglobin formation.
    Stefani C; Jansson PJ; Gutierrez E; Bernhardt PV; Richardson DR; Kalinowski DS
    J Med Chem; 2013 Jan; 56(1):357-70. PubMed ID: 23276209
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of the di-pyridyl ketone isonicotinoyl hydrazone (PKIH) analogues as potent iron chelators and anti-tumour agents.
    Becker EM; Lovejoy DB; Greer JM; Watts R; Richardson DR
    Br J Pharmacol; 2003 Mar; 138(5):819-30. PubMed ID: 12642383
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and characterization of thiosemicarbazones with antifungal and antitumor effects: cellular iron chelation mediating cytotoxic activity.
    Opletalová V; Kalinowski DS; Vejsová M; Kunes J; Pour M; Jampílek J; Buchta V; Richardson DR
    Chem Res Toxicol; 2008 Sep; 21(9):1878-89. PubMed ID: 18698850
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Unprecedented oxidation of a biologically active aroylhydrazone chelator catalysed by iron(III): serendipitous identification of diacylhydrazine ligands with high iron chelation efficacy.
    Bernhardt PV; Chin P; Richardson DR
    J Biol Inorg Chem; 2001 Oct; 6(8):801-9. PubMed ID: 11713687
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel "hybrid" iron chelators derived from aroylhydrazones and thiosemicarbazones demonstrate selective antiproliferative activity against tumor cells.
    Lovejoy DB; Richardson DR
    Blood; 2002 Jul; 100(2):666-76. PubMed ID: 12091363
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methyl and ethyl ketone analogs of salicylaldehyde isonicotinoyl hydrazone: novel iron chelators with selective antiproliferative action.
    Macková E; Hrušková K; Bendová P; Vávrová A; Jansová H; Hašková P; Kovaříková P; Vávrová K; Simůnek T
    Chem Biol Interact; 2012 May; 197(2-3):69-79. PubMed ID: 22521999
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Iron chelators of the dipyridylketone thiosemicarbazone class: precomplexation and transmetalation effects on anticancer activity.
    Bernhardt PV; Sharpe PC; Islam M; Lovejoy DB; Kalinowski DS; Richardson DR
    J Med Chem; 2009 Jan; 52(2):407-15. PubMed ID: 19090766
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation.
    Chaston TB; Watts RN; Yuan J; Richardson DR
    Clin Cancer Res; 2004 Nov; 10(21):7365-74. PubMed ID: 15534113
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Complexes of cytotoxic chelators from the dipyridyl ketone isonicotinoyl hydrazone (HPKIH) analogues.
    Bernhardt PV; Mattsson J; Richardson DR
    Inorg Chem; 2006 Jan; 45(2):752-60. PubMed ID: 16411711
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel thiosemicarbazones of the ApT and DpT series and their copper complexes: identification of pronounced redox activity and characterization of their antitumor activity.
    Jansson PJ; Sharpe PC; Bernhardt PV; Richardson DR
    J Med Chem; 2010 Aug; 53(15):5759-69. PubMed ID: 20597487
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of novel aroylhydrazone ligands for iron chelation therapy: 2-pyridylcarboxaldehyde isonicotinoyl hydrazone analogs.
    Becker E; Richardson DR
    J Lab Clin Med; 1999 Nov; 134(5):510-21. PubMed ID: 10560945
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Halogenated 2'-benzoylpyridine thiosemicarbazone (XBpT) chelators with potent and selective anti-neoplastic activity: relationship to intracellular redox activity.
    Stefani C; Punnia-Moorthy G; Lovejoy DB; Jansson PJ; Kalinowski DS; Sharpe PC; Bernhardt PV; Richardson DR
    J Med Chem; 2011 Oct; 54(19):6936-48. PubMed ID: 21846118
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and characterization of quinoline-based thiosemicarbazones and correlation of cellular iron-binding efficacy to anti-tumor efficacy.
    Serda M; Kalinowski DS; Mrozek-Wilczkiewicz A; Musiol R; Szurko A; Ratuszna A; Pantarat N; Kovacevic Z; Merlot AM; Richardson DR; Polanski J
    Bioorg Med Chem Lett; 2012 Sep; 22(17):5527-31. PubMed ID: 22858101
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dipyridyl thiosemicarbazone chelators with potent and selective antitumor activity form iron complexes with redox activity.
    Richardson DR; Sharpe PC; Lovejoy DB; Senaratne D; Kalinowski DS; Islam M; Bernhardt PV
    J Med Chem; 2006 Nov; 49(22):6510-21. PubMed ID: 17064069
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and in vitro antitumor activity of new 1,4-diarylimidazole-2-ones and their 2-thione analogues.
    Congiu C; Cocco MT; Onnis V
    Bioorg Med Chem Lett; 2008 Feb; 18(3):989-93. PubMed ID: 18164978
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protection against hydrogen peroxide-mediated cytotoxicity in Friedreich's ataxia fibroblasts using novel iron chelators of the 2-pyridylcarboxaldehyde isonicotinoyl hydrazone class.
    Lim CK; Kalinowski DS; Richardson DR
    Mol Pharmacol; 2008 Jul; 74(1):225-35. PubMed ID: 18424550
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.