BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 17964154)

  • 1. Development of CXCR3 antagonists. Part 2: Identification of 2-amino(4-piperidinyl)azoles as potent CXCR3 antagonists.
    Watson RJ; Allen DR; Birch HL; Chapman GA; Hannah DR; Knight RL; Meissner JW; Owen DA; Thomas EJ
    Bioorg Med Chem Lett; 2007 Dec; 17(24):6806-10. PubMed ID: 17964154
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lead identification of 2-iminobenzimidazole antagonists of the chemokine receptor CXCR3.
    Hayes ME; Breinlinger EC; Wallace GA; Grongsaard P; Miao W; McPherson MJ; Stoffel RH; Green DW; Roth GP
    Bioorg Med Chem Lett; 2008 Apr; 18(7):2414-9. PubMed ID: 18337097
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of CXCR3 antagonists. Part 3: Tropenyl and homotropenyl-piperidine urea derivatives.
    Watson RJ; Allen DR; Birch HL; Chapman GA; Galvin FC; Jopling LA; Knight RL; Meier D; Oliver K; Meissner JW; Owen DA; Thomas EJ; Tremayne N; Williams SC
    Bioorg Med Chem Lett; 2008 Jan; 18(1):147-51. PubMed ID: 18032038
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of CXCR3 antagonists. Part 4: discovery of 2-amino-(4-tropinyl)quinolines.
    Knight RL; Allen DR; Birch HL; Chapman GA; Galvin FC; Jopling LA; Lock CJ; Meissner JW; Owen DA; Raphy G; Watson RJ; Williams SC
    Bioorg Med Chem Lett; 2008 Jan; 18(2):629-33. PubMed ID: 18068363
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and optimization of imidazole derivatives as potent CXCR3 antagonists.
    Du X; Chen X; Mihalic JT; Deignan J; Duquette J; Li AR; Lemon B; Ma J; Miao S; Ebsworth K; Sullivan TJ; Tonn G; Collins TL; Medina JC
    Bioorg Med Chem Lett; 2008 Jan; 18(2):608-13. PubMed ID: 18063364
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of 3-piperidinyl-1-cyclopentanecarboxamide as a novel scaffold for highly potent CC chemokine receptor 2 antagonists.
    Yang L; Butora G; Jiao RX; Pasternak A; Zhou C; Parsons WH; Mills SG; Vicario PP; Ayala JM; Cascieri MA; MacCoss M
    J Med Chem; 2007 May; 50(11):2609-11. PubMed ID: 17461566
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological evaluation of piperidine-4-carboxamide derivatives.
    Imamura S; Nishikawa Y; Ichikawa T; Hattori T; Matsushita Y; Hashiguchi S; Kanzaki N; Iizawa Y; Baba M; Sugihara Y
    Bioorg Med Chem; 2005 Jan; 13(2):397-416. PubMed ID: 15598561
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and structure-activity relationship of benzetimide derivatives as human CXCR3 antagonists.
    Bongartz JP; Buntinx M; Coesemans E; Hermans B; Lommen GV; Wauwe JV
    Bioorg Med Chem Lett; 2008 Nov; 18(21):5819-23. PubMed ID: 18922694
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Camphor sulfonamide derivatives as novel, potent and selective CXCR3 antagonists.
    Wang Y; Busch-Petersen J; Wang F; Kiesow TJ; Graybill TL; Jin J; Yang Z; Foley JJ; Hunsberger GE; Schmidt DB; Sarau HM; Capper-Spudich EA; Wu Z; Fisher LS; McQueney MS; Rivero RA; Widdowson KL
    Bioorg Med Chem Lett; 2009 Jan; 19(1):114-8. PubMed ID: 19014886
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification and structure-activity relationships of 1-aryl-3-piperidin-4-yl-urea derivatives as CXCR3 receptor antagonists.
    Allen DR; Bolt A; Chapman GA; Knight RL; Meissner JW; Owen DA; Watson RJ
    Bioorg Med Chem Lett; 2007 Feb; 17(3):697-701. PubMed ID: 17097877
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Azole endothelin antagonists. 2. Structure-activity studies.
    von Geldern TW; Kester JA; Bal R; Wu-Wong JR; Chiou W; Dixon DB; Opgenorth TJ
    J Med Chem; 1996 Feb; 39(4):968-81. PubMed ID: 8632420
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of a novel 4-aminomethylpiperidine class of M3 muscarinic receptor antagonists and structural insight into their M3 selectivity.
    Sagara Y; Sagara T; Uchiyama M; Otsuki S; Kimura T; Fujikawa T; Noguchi K; Ohtake N
    J Med Chem; 2006 Sep; 49(19):5653-63. PubMed ID: 16970392
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modulators of the human CCR5 receptor. Part 2: SAR of substituted 1-(3,3-diphenylpropyl)-piperidinyl phenylacetamides.
    Cumming JG; Cooper AE; Grime K; Logan CJ; McLaughlin S; Oldfield J; Shaw JS; Tucker H; Winter J; Whittaker D
    Bioorg Med Chem Lett; 2005 Nov; 15(22):5012-5. PubMed ID: 16154744
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases.
    Bey E; Marchais-Oberwinkler S; Kruchten P; Frotscher M; Werth R; Oster A; Algül O; Neugebauer A; Hartmann RW
    Bioorg Med Chem; 2008 Jun; 16(12):6423-35. PubMed ID: 18514529
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Towards small-molecule CXCR3 ligands with clinical potential.
    Wijtmans M; Verzijl D; Leurs R; de Esch IJ; Smit MJ
    ChemMedChem; 2008 Jun; 3(6):861-72. PubMed ID: 18442035
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and SAR of substituted tetrahydrocarbazole derivatives as new NPY-1 antagonists.
    Di Fabio R; Giovannini R; Bertani B; Borriello M; Bozzoli A; Donati D; Falchi A; Ghirlanda D; Leslie CP; Pecunioso A; Rumboldt G; Spada S
    Bioorg Med Chem Lett; 2006 Mar; 16(6):1749-52. PubMed ID: 16364642
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological activity of 5-aryl-4-(4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl)pyrimidine analogs as potent, highly selective, and orally bioavailable NHE-1 inhibitors.
    Atwal KS; O'Neil SV; Ahmad S; Doweyko L; Kirby M; Dorso CR; Chandrasena G; Chen BC; Zhao R; Zahler R
    Bioorg Med Chem Lett; 2006 Sep; 16(18):4796-9. PubMed ID: 16870436
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulators of the human CCR5 receptor. Part 3: SAR of substituted 1-[3-(4-methanesulfonylphenyl)-3-phenylpropyl]-piperidinyl phenylacetamides.
    Cumming JG; Brown SJ; Cooper AE; Faull AW; Flynn AP; Grime K; Oldfield J; Shaw JS; Shepherd E; Tucker H; Whittaker D
    Bioorg Med Chem Lett; 2006 Jul; 16(13):3533-6. PubMed ID: 16631366
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel QSAR model for predicting the inhibition of CXCR3 receptor by 4-N-aryl-[1,4] diazepane ureas.
    Afantitis A; Melagraki G; Sarimveis H; Igglessi-Markopoulou O; Kollias G
    Eur J Med Chem; 2009 Feb; 44(2):877-84. PubMed ID: 18619714
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antagonists of the human A(2A) adenosine receptor. 4. Design, synthesis, and preclinical evaluation of 7-aryltriazolo[4,5-d]pyrimidines.
    Gillespie RJ; Bamford SJ; Botting R; Comer M; Denny S; Gaur S; Griffin M; Jordan AM; Knight AR; Lerpiniere J; Leonardi S; Lightowler S; McAteer S; Merrett A; Misra A; Padfield A; Reece M; Saadi M; Selwood DL; Stratton GC; Surry D; Todd R; Tong X; Ruston V; Upton R; Weiss SM
    J Med Chem; 2009 Jan; 52(1):33-47. PubMed ID: 19072055
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.