These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 17965014)

  • 1. Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b.
    Martin L; Fluhrer R; Reiss K; Kremmer E; Saftig P; Haass C
    J Biol Chem; 2008 Jan; 283(3):1644-1652. PubMed ID: 17965014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The α-helical content of the transmembrane domain of the British dementia protein-2 (Bri2) determines its processing by signal peptide peptidase-like 2b (SPPL2b).
    Fluhrer R; Martin L; Klier B; Haug-Kröper M; Grammer G; Nuscher B; Haass C
    J Biol Chem; 2012 Feb; 287(7):5156-63. PubMed ID: 22194595
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysis.
    Martin L; Fluhrer R; Haass C
    J Biol Chem; 2009 Feb; 284(9):5662-70. PubMed ID: 19114711
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Physiological functions of SPP/SPPL intramembrane proteases.
    Mentrup T; Cabrera-Cabrera F; Fluhrer R; Schröder B
    Cell Mol Life Sci; 2020 Aug; 77(15):2959-2979. PubMed ID: 32052089
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism, specificity, and physiology of signal peptide peptidase (SPP) and SPP-like proteases.
    Voss M; Schröder B; Fluhrer R
    Biochim Biophys Acta; 2013 Dec; 1828(12):2828-39. PubMed ID: 24099004
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Foamy virus envelope protein is a substrate for signal peptide peptidase-like 3 (SPPL3).
    Voss M; Fukumori A; Kuhn PH; Künzel U; Klier B; Grammer G; Haug-Kröper M; Kremmer E; Lichtenthaler SF; Steiner H; Schröder B; Haass C; Fluhrer R
    J Biol Chem; 2012 Dec; 287(52):43401-9. PubMed ID: 23132852
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The role of SPP/SPPL intramembrane proteases in membrane protein homeostasis.
    Mentrup T; Leinung N; Patel M; Fluhrer R; Schröder B
    FEBS J; 2024 Jan; 291(1):25-44. PubMed ID: 37625440
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b.
    Fluhrer R; Grammer G; Israel L; Condron MM; Haffner C; Friedmann E; Böhland C; Imhof A; Martoglio B; Teplow DB; Haass C
    Nat Cell Biol; 2006 Aug; 8(8):894-6. PubMed ID: 16829951
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Signal peptide peptidase and SPP-like proteases - Possible therapeutic targets?
    Mentrup T; Loock AC; Fluhrer R; Schröder B
    Biochim Biophys Acta Mol Cell Res; 2017 Nov; 1864(11 Pt B):2169-2182. PubMed ID: 28624439
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Latest emerging functions of SPP/SPPL intramembrane proteases.
    Mentrup T; Fluhrer R; Schröder B
    Eur J Cell Biol; 2017 Aug; 96(5):372-382. PubMed ID: 28366434
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Signal peptide peptidases and gamma-secretase: cousins of the same protease family?
    Fluhrer R; Haass C
    Neurodegener Dis; 2007; 4(2-3):112-6. PubMed ID: 17596705
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3.
    Krawitz P; Haffner C; Fluhrer R; Steiner H; Schmid B; Haass C
    J Biol Chem; 2005 Nov; 280(47):39515-23. PubMed ID: 15998642
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase Inhibitors.
    Ran Y; Ladd GZ; Ceballos-Diaz C; Jung JI; Greenbaum D; Felsenstein KM; Golde TE
    PLoS One; 2015; 10(6):e0128619. PubMed ID: 26046535
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glycosylation of BRI2 on asparagine 170 is involved in its trafficking to the cell surface but not in its processing by furin or ADAM10.
    Tsachaki M; Serlidaki D; Fetani A; Zarkou V; Rozani I; Ghiso J; Efthimiopoulos S
    Glycobiology; 2011 Oct; 21(10):1382-8. PubMed ID: 21752865
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intramembrane proteolysis of GXGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation.
    Fluhrer R; Fukumori A; Martin L; Grammer G; Haug-Kröper M; Klier B; Winkler E; Kremmer E; Condron MM; Teplow DB; Steiner H; Haass C
    J Biol Chem; 2008 Oct; 283(44):30121-8. PubMed ID: 18768471
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Signaling Functions of Intramembrane Aspartyl-Proteases.
    Papadopoulou AA; Fluhrer R
    Front Cardiovasc Med; 2020; 7():591787. PubMed ID: 33381526
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The intramembrane proteases SPPL2a and SPPL2b regulate the homeostasis of selected SNARE proteins.
    Ballin M; Griep W; Patel M; Karl M; Mentrup T; Rivera-Monroy J; Foo B; Schwappach B; Schröder B
    FEBS J; 2023 May; 290(9):2320-2337. PubMed ID: 36047592
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase.
    Tousseyn T; Thathiah A; Jorissen E; Raemaekers T; Konietzko U; Reiss K; Maes E; Snellinx A; Serneels L; Nyabi O; Annaert W; Saftig P; Hartmann D; De Strooper B
    J Biol Chem; 2009 Apr; 284(17):11738-47. PubMed ID: 19213735
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases.
    Fleck D; Voss M; Brankatschk B; Giudici C; Hampel H; Schwenk B; Edbauer D; Fukumori A; Steiner H; Kremmer E; Haug-Kröper M; Rossner MJ; Fluhrer R; Willem M; Haass C
    J Biol Chem; 2016 Jan; 291(1):318-33. PubMed ID: 26574544
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).
    Brady OA; Zhou X; Hu F
    J Biol Chem; 2014 Jul; 289(28):19670-80. PubMed ID: 24872421
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.