These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 17965852)

  • 1. Anticholinergic antiparkinson drug orphenadrine inhibits HERG channels: block attenuation by mutations of the pore residues Y652 or F656.
    Scholz EP; Konrad FM; Weiss DL; Zitron E; Kiesecker C; Bloehs R; Kulzer M; Thomas D; Kathöfer S; Bauer A; Maurer MH; Seemann G; Katus HA; Karle CA
    Naunyn Schmiedebergs Arch Pharmacol; 2007 Dec; 376(4):275-84. PubMed ID: 17965852
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine.
    Scholz EP; Zitron E; Kiesecker C; Lueck S; Kathöfer S; Thomas D; Weretka S; Peth S; Kreye VA; Schoels W; Katus HA; Kiehn J; Karle CA
    Naunyn Schmiedebergs Arch Pharmacol; 2003 Nov; 368(5):404-14. PubMed ID: 14557918
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine.
    Sánchez-Chapula JA; Navarro-Polanco RA; Sanguinetti MC
    Naunyn Schmiedebergs Arch Pharmacol; 2004 Dec; 370(6):484-91. PubMed ID: 15558243
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells.
    Jehle J; Ficker E; Wan X; Deschenes I; Kisselbach J; Wiedmann F; Staudacher I; Schmidt C; Schweizer PA; Becker R; Katus HA; Thomas D
    Br J Pharmacol; 2013 Mar; 168(5):1215-29. PubMed ID: 23061993
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action.
    Thomas D; Hammerling BC; Wu K; Wimmer AB; Ficker EK; Kirsch GE; Kochan MC; Wible BA; Scholz EP; Zitron E; Kathöfer S; Kreye VA; Katus HA; Schoels W; Karle CA; Kiehn J
    Br J Pharmacol; 2004 Jun; 142(3):485-94. PubMed ID: 15148258
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Open channel block of HERG K(+) channels by vesnarinone.
    Kamiya K; Mitcheson JS; Yasui K; Kodama I; Sanguinetti MC
    Mol Pharmacol; 2001 Aug; 60(2):244-53. PubMed ID: 11455010
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872.
    Thomas D; Wendt-Nordahl G; Röckl K; Ficker E; Brown AM; Kiehn J
    J Pharmacol Exp Ther; 2001 May; 297(2):753-61. PubMed ID: 11303067
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action.
    Kiesecker C; Zitron E; Lück S; Bloehs R; Scholz EP; Kathöfer S; Thomas D; Kreye VA; Katus HA; Schoels W; Karle CA; Kiehn J
    Naunyn Schmiedebergs Arch Pharmacol; 2004 Dec; 370(6):423-35. PubMed ID: 15599706
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Clomipramine block of the hERG K+ channel: accessibility to F656 and Y652.
    Jo SH; Hong HK; Chong SH; Won KH; Jung SJ; Choe H
    Eur J Pharmacol; 2008 Sep; 592(1-3):19-25. PubMed ID: 18634780
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine.
    Obers S; Staudacher I; Ficker E; Dennis A; Koschny R; Erdal H; Bloehs R; Kisselbach J; Karle CA; Schweizer PA; Katus HA; Thomas D
    Naunyn Schmiedebergs Arch Pharmacol; 2010 May; 381(5):385-400. PubMed ID: 20229012
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652.
    Milnes JT; Crociani O; Arcangeli A; Hancox JC; Witchel HJ
    Br J Pharmacol; 2003 Jul; 139(5):887-98. PubMed ID: 12839862
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Atypical tetracyclic antidepressant maprotiline is an antagonist at cardiac hERG potassium channels.
    Kiesecker C; Alter M; Kathöfer S; Zitron E; Scholz EP; Thomas D; Kreuzer J; Katus HA; Bauer A; Karle CA
    Naunyn Schmiedebergs Arch Pharmacol; 2006 Jun; 373(3):212-20. PubMed ID: 16736158
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural requirements of human ether-a-go-go-related gene channels for block by bupivacaine.
    Siebrands CC; Friederich P
    Anesthesiology; 2007 Mar; 106(3):523-31. PubMed ID: 17325511
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of the HERG channel by droperidol depends on channel gating and involves the S6 residue F656.
    Luo T; Luo A; Liu M; Liu X
    Anesth Analg; 2008 Apr; 106(4):1161-70, table of contents. PubMed ID: 18349188
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Procaine, a state-dependent blocker, inhibits HERG channels by helix residue Y652 and F656 in the S6 transmembrane domain.
    Wang N; Ma JH; Zhang PH
    J Pharmacol Sci; 2013 Sep; 123(1):25-35. PubMed ID: 24005047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform.
    Scholz EP; Alter M; Zitron E; Kiesecker C; Kathöfer S; Thomas D; Kreye VA; Kreuzer J; Becker R; Katus HA; Greten J; Karle CA
    Toxicol Lett; 2006 Aug; 165(2):156-66. PubMed ID: 16647228
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Verapamil blocks HERG channel by the helix residue Y652 and F656 in the S6 transmembrane domain.
    Duan JJ; Ma JH; Zhang PH; Wang XP; Zou AR; Tu DN
    Acta Pharmacol Sin; 2007 Jul; 28(7):959-67. PubMed ID: 17588331
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acute and subacute effects of the selective serotonin-noradrenaline reuptake inhibitor duloxetine on cardiac hERG channels.
    Fischer F; Vonderlin N; Seyler C; Zitron E; Schernus B; Katus H; Scholz E
    Naunyn Schmiedebergs Arch Pharmacol; 2013 Sep; 386(9):795-804. PubMed ID: 23666493
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin.
    Thomas D; Wimmer AB; Wu K; Hammerling BC; Ficker EK; Kuryshev YA; Kiehn J; Katus HA; Schoels W; Karle CA
    Naunyn Schmiedebergs Arch Pharmacol; 2004 May; 369(5):462-72. PubMed ID: 15098086
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of cardiac HERG channels by grapefruit flavonoid naringenin: implications for the influence of dietary compounds on cardiac repolarisation.
    Scholz EP; Zitron E; Kiesecker C; Lück S; Thomas D; Kathöfer S; Kreye VA; Katus HA; Kiehn J; Schoels W; Karle CA
    Naunyn Schmiedebergs Arch Pharmacol; 2005 Jun; 371(6):516-25. PubMed ID: 16007460
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.