281 related articles for article (PubMed ID: 17967933)
1. Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells.
Acharya P; O'Connor MP; Polli JW; Ayrton A; Ellens H; Bentz J
Drug Metab Dispos; 2008 Feb; 36(2):452-60. PubMed ID: 17967933
[TBL] [Abstract][Full Text] [Related]
2. P-Glycoprotein (P-gp) expressed in a confluent monolayer of hMDR1-MDCKII cells has more than one efflux pathway with cooperative binding sites.
Acharya P; Tran TT; Polli JW; Ayrton A; Ellens H; Bentz J
Biochemistry; 2006 Dec; 45(51):15505-19. PubMed ID: 17176072
[TBL] [Abstract][Full Text] [Related]
3. Fitting the elementary rate constants of the P-gp transporter network in the hMDR1-MDCK confluent cell monolayer using a particle swarm algorithm.
Agnani D; Acharya P; Martinez E; Tran TT; Abraham F; Tobin F; Ellens H; Bentz J
PLoS One; 2011; 6(10):e25086. PubMed ID: 22028772
[TBL] [Abstract][Full Text] [Related]
4. The elementary mass action rate constants of P-gp transport for a confluent monolayer of MDCKII-hMDR1 cells.
Tran TT; Mittal A; Aldinger T; Polli JW; Ayrton A; Ellens H; Bentz J
Biophys J; 2005 Jan; 88(1):715-38. PubMed ID: 15501934
[TBL] [Abstract][Full Text] [Related]
5. Extrapolation of Elementary Rate Constants of P-glycoprotein-Mediated Transport from MDCKII-hMDR1-NKI to Caco-2 Cells.
Meng Z; Ellens H; Bentz J
Drug Metab Dispos; 2017 Feb; 45(2):190-197. PubMed ID: 27856526
[TBL] [Abstract][Full Text] [Related]
6. Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp.
Lumen AA; Li L; Li J; Ahmed Z; Meng Z; Owen A; Ellens H; Hidalgo IJ; Bentz J
PLoS One; 2013; 8(8):e69394. PubMed ID: 23976943
[TBL] [Abstract][Full Text] [Related]
7. Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity.
Taub ME; Podila L; Ely D; Almeida I
Drug Metab Dispos; 2005 Nov; 33(11):1679-87. PubMed ID: 16093365
[TBL] [Abstract][Full Text] [Related]
8. If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer?
Lumen AA; Acharya P; Polli JW; Ayrton A; Ellens H; Bentz J
Drug Metab Dispos; 2010 Feb; 38(2):260-9. PubMed ID: 19889884
[TBL] [Abstract][Full Text] [Related]
9. Comparison of drug efflux transport kinetics in various blood-brain barrier models.
Bachmeier CJ; Trickler WJ; Miller DW
Drug Metab Dispos; 2006 Jun; 34(6):998-1003. PubMed ID: 16554372
[TBL] [Abstract][Full Text] [Related]
10. A combined cell based approach to identify P-glycoprotein substrates and inhibitors in a single assay.
Balimane PV; Chong S
Int J Pharm; 2005 Sep; 301(1-2):80-8. PubMed ID: 16023314
[TBL] [Abstract][Full Text] [Related]
11. Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).
Tanigawara Y; Okamura N; Hirai M; Yasuhara M; Ueda K; Kioka N; Komano T; Hori R
J Pharmacol Exp Ther; 1992 Nov; 263(2):840-5. PubMed ID: 1359120
[TBL] [Abstract][Full Text] [Related]
12. The steady-state Michaelis-Menten analysis of P-glycoprotein mediated transport through a confluent cell monolayer cannot predict the correct Michaelis constant Km.
Bentz J; Tran TT; Polli JW; Ayrton A; Ellens H
Pharm Res; 2005 Oct; 22(10):1667-77. PubMed ID: 16180124
[TBL] [Abstract][Full Text] [Related]
13. Case Study 8: Status of the Structural Mass Action Kinetic Model of P-gp-Mediated Transport Through Confluent Cell Monolayers.
Bentz J; Ellens H
Methods Mol Biol; 2021; 2342():737-763. PubMed ID: 34272715
[TBL] [Abstract][Full Text] [Related]
14. Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein.
Keogh JP; Kunta JR
Eur J Pharm Sci; 2006 Apr; 27(5):543-54. PubMed ID: 16406207
[TBL] [Abstract][Full Text] [Related]
15. Caco-2 cell methodology and inhibition of the P-glycoprotein transport of digoxin by Aloe vera juice.
Djuv A; Nilsen OG
Phytother Res; 2008 Dec; 22(12):1623-8. PubMed ID: 19003953
[TBL] [Abstract][Full Text] [Related]
16. Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein.
Woodahl EL; Yang Z; Bui T; Shen DD; Ho RJ
J Pharmacol Exp Ther; 2004 Sep; 310(3):1199-207. PubMed ID: 15100388
[TBL] [Abstract][Full Text] [Related]
17. Role of P-glycoprotein and the intestine in the excretion of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in rodents.
Garner CE; Solon E; Lai CM; Lin J; Luo G; Jones K; Duan J; Decicco CP; Maduskuie T; Mercer SE; Gan LS; Qian M; Prakash S; Shen HS; Lee FW
Drug Metab Dispos; 2008 Jun; 36(6):1102-10. PubMed ID: 18347085
[TBL] [Abstract][Full Text] [Related]
18. Functional role of P-glycoprotein in limiting intestinal absorption of drugs: contribution of passive permeability to P-glycoprotein mediated efflux transport.
Varma MV; Sateesh K; Panchagnula R
Mol Pharm; 2005; 2(1):12-21. PubMed ID: 15804173
[TBL] [Abstract][Full Text] [Related]
19. A structural model for the mass action kinetic analysis of P-gp mediated transport through confluent cell monolayers.
Bentz J; Ellens H
Methods Mol Biol; 2014; 1113():289-316. PubMed ID: 24523118
[TBL] [Abstract][Full Text] [Related]
20. Derivation of a System-Independent
Chaudhry A; Chung G; Lynn A; Yalvigi A; Brown C; Ellens H; O'Connor M; Lee C; Bentz J
Drug Metab Dispos; 2018 Mar; 46(3):279-290. PubMed ID: 29317410
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]