These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. The ubiquitin ligase COP1 is a critical negative regulator of p53. Dornan D; Wertz I; Shimizu H; Arnott D; Frantz GD; Dowd P; O'Rourke K; Koeppen H; Dixit VM Nature; 2004 May; 429(6987):86-92. PubMed ID: 15103385 [TBL] [Abstract][Full Text] [Related]
3. The E3 ubiquitin ligase complex component COP1 regulates PEA3 group member stability and transcriptional activity. Baert JL; Monte D; Verreman K; Degerny C; Coutte L; de Launoit Y Oncogene; 2010 Mar; 29(12):1810-20. PubMed ID: 20062082 [TBL] [Abstract][Full Text] [Related]
4. Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice. Migliorini D; Bogaerts S; Defever D; Vyas R; Denecker G; Radaelli E; Zwolinska A; Depaepe V; Hochepied T; Skarnes WC; Marine JC J Clin Invest; 2011 Apr; 121(4):1329-43. PubMed ID: 21403399 [TBL] [Abstract][Full Text] [Related]
5. COP1 and GSK3β cooperate to promote c-Jun degradation and inhibit breast cancer cell tumorigenesis. Shao J; Teng Y; Padia R; Hong S; Noh H; Xie X; Mumm JS; Dong Z; Ding HF; Cowell J; Kim J; Han J; Huang S Neoplasia; 2013 Sep; 15(9):1075-85. PubMed ID: 24027432 [TBL] [Abstract][Full Text] [Related]
6. Constitutive photomorphogenesis protein 1 (COP1) and COP9 signalosome, evolutionarily conserved photomorphogenic proteins as possible targets of melatonin. Sanchez-Barcelo EJ; Mediavilla MD; Vriend J; Reiter RJ J Pineal Res; 2016 Aug; 61(1):41-51. PubMed ID: 27121162 [TBL] [Abstract][Full Text] [Related]
7. Good COP1 or bad COP1? In vivo veritas. Wei W; Kaelin WG J Clin Invest; 2011 Apr; 121(4):1263-5. PubMed ID: 21403396 [TBL] [Abstract][Full Text] [Related]
8. The Ubiquitin Ligase COP1 Promotes Glioma Cell Proliferation by Preferentially Downregulating Tumor Suppressor p53. Zou S; Zhu Y; Wang B; Qian F; Zhang X; Wang L; Fu C; Bao H; Xie M; Gao S; Yu R; Shi H Mol Neurobiol; 2017 Sep; 54(7):5008-5016. PubMed ID: 27534417 [TBL] [Abstract][Full Text] [Related]
9. The ubiquitin ligase COP1 regulates cell cycle and apoptosis by affecting p53 function in human breast cancer cell lines. Ka WH; Cho SK; Chun BN; Byun SY; Ahn JC Breast Cancer; 2018 Sep; 25(5):529-538. PubMed ID: 29516369 [TBL] [Abstract][Full Text] [Related]
10. Major vault protein, in concert with constitutively photomorphogenic 1, negatively regulates c-Jun-mediated activator protein 1 transcription in mammalian cells. Yi C; Li S; Chen X; Wiemer EA; Wang J; Wei N; Deng XW Cancer Res; 2005 Jul; 65(13):5835-40. PubMed ID: 15994960 [TBL] [Abstract][Full Text] [Related]
11. ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage. Dornan D; Shimizu H; Mah A; Dudhela T; Eby M; O'rourke K; Seshagiri S; Dixit VM Science; 2006 Aug; 313(5790):1122-6. PubMed ID: 16931761 [TBL] [Abstract][Full Text] [Related]
12. COP1, the negative regulator of p53, is overexpressed in breast and ovarian adenocarcinomas. Dornan D; Bheddah S; Newton K; Ince W; Frantz GD; Dowd P; Koeppen H; Dixit VM; French DM Cancer Res; 2004 Oct; 64(20):7226-30. PubMed ID: 15492238 [TBL] [Abstract][Full Text] [Related]
13. COP1 - from plant photomorphogenesis to mammalian tumorigenesis. Yi C; Deng XW Trends Cell Biol; 2005 Nov; 15(11):618-25. PubMed ID: 16198569 [TBL] [Abstract][Full Text] [Related]
14. 14-3-3sigma exerts tumor-suppressor activity mediated by regulation of COP1 stability. Su CH; Zhao R; Zhang F; Qu C; Chen B; Feng YH; Phan L; Chen J; Wang H; Wang H; Yeung SC; Lee MH Cancer Res; 2011 Feb; 71(3):884-94. PubMed ID: 21135113 [TBL] [Abstract][Full Text] [Related]
15. Transcriptional repression of c-Jun's E3 ubiquitin ligases contributes to c-Jun induction by UV. Anzi S; Finkin S; Shaulian E Cell Signal; 2008 May; 20(5):862-71. PubMed ID: 18295447 [TBL] [Abstract][Full Text] [Related]
16. Erk1/2 inactivation promotes a rapid redistribution of COP1 and degradation of COP1 substrates. Ouyang W; Guo P; Takeda K; Fu Q; Fang H; Frucht DM Proc Natl Acad Sci U S A; 2020 Feb; 117(8):4078-4087. PubMed ID: 32041890 [TBL] [Abstract][Full Text] [Related]
17. COP1 Acts as a Ubiquitin Ligase for PCDH9 Ubiquitination and Degradation in Human Glioma. Zhou K; Wang L; Sun Z; Liu Y; Zhu Y; Liu Z; Zhang B; Shi H Mol Neurobiol; 2022 Apr; 59(4):2378-2388. PubMed ID: 35084653 [TBL] [Abstract][Full Text] [Related]
18. The splice 1 variant of HTLV-1 bZIP factor stabilizes c-Jun. Polakowski N; Pearce M; Kuguyo O; Boateng G; Hoang K; Lemasson I Virology; 2020 Oct; 549():51-58. PubMed ID: 32841759 [TBL] [Abstract][Full Text] [Related]
19. COP1 enhances ubiquitin-mediated degradation of p27Kip1 to promote cancer cell growth. Choi HH; Phan L; Chou PC; Su CH; Yeung SC; Chen JS; Lee MH Oncotarget; 2015 Aug; 6(23):19721-34. PubMed ID: 26254224 [TBL] [Abstract][Full Text] [Related]
20. The E3 ligase COP1 promotes ERα signaling and suppresses EMT in breast cancer. Tang SC; Lion Q; Peulen O; Chariot P; Lavergne A; Mayer A; Fuster PA; Close P; Klein S; Florin A; Büttner R; Nemazanyy I; Shostak K; Chariot A Oncogene; 2022 Jan; 41(2):173-190. PubMed ID: 34716429 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]