340 related articles for article (PubMed ID: 17971900)
1. Targeting antiapoptotic Bcl-2 family members with cell-permeable BH3 peptides induces apoptosis signaling and death in head and neck squamous cell carcinoma cells.
Li R; Boehm AL; Miranda MB; Shangary S; Grandis JR; Johnson DE
Neoplasia; 2007 Oct; 9(10):801-11. PubMed ID: 17971900
[TBL] [Abstract][Full Text] [Related]
2. Sequence and helicity requirements for the proapoptotic activity of Bax BH3 peptides.
Shangary S; Oliver CL; Tillman TS; Cascio M; Johnson DE
Mol Cancer Ther; 2004 Nov; 3(11):1343-54. PubMed ID: 15542773
[TBL] [Abstract][Full Text] [Related]
3. Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases.
Holinger EP; Chittenden T; Lutz RJ
J Biol Chem; 1999 May; 274(19):13298-304. PubMed ID: 10224090
[TBL] [Abstract][Full Text] [Related]
4. The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.
Sung ES; Park KJ; Choi HJ; Kim CH; Kim YS
Exp Cell Res; 2012 Aug; 318(13):1564-76. PubMed ID: 22513214
[TBL] [Abstract][Full Text] [Related]
5. In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells.
Oliver CL; Bauer JA; Wolter KG; Ubell ML; Narayan A; O'Connell KM; Fisher SG; Wang S; Wu X; Ji M; Carey TE; Bradford CR
Clin Cancer Res; 2004 Nov; 10(22):7757-63. PubMed ID: 15570010
[TBL] [Abstract][Full Text] [Related]
6. Hypertonicity counteracts MCL-1 and renders BCL-XL a synthetic lethal target in head and neck cancer.
Heimer S; Knoll G; Neubert P; Hammer KP; Wagner S; Bauer RJ; Jantsch J; Ehrenschwender M
FEBS J; 2021 Mar; 288(6):1822-1838. PubMed ID: 32710568
[TBL] [Abstract][Full Text] [Related]
7. Peptides derived from BH3 domains of Bcl-2 family members: a comparative analysis of inhibition of Bcl-2, Bcl-x(L) and Bax oligomerization, induction of cytochrome c release, and activation of cell death.
Shangary S; Johnson DE
Biochemistry; 2002 Jul; 41(30):9485-95. PubMed ID: 12135371
[TBL] [Abstract][Full Text] [Related]
8. Optimization and validation of mitochondria-based functional assay as a useful tool to identify BH3-like molecules selectively targeting anti-apoptotic Bcl-2 proteins.
Long J; Liu L; Nikolovska-Coleska Z; Shangary S; Yi H; Wang S; Wang S
BMC Biotechnol; 2013 May; 13():45. PubMed ID: 23705845
[TBL] [Abstract][Full Text] [Related]
9. Differences in the mechanisms of proapoptotic BH3 proteins binding to Bcl-XL and Bcl-2 quantified in live MCF-7 cells.
Aranovich A; Liu Q; Collins T; Geng F; Dixit S; Leber B; Andrews DW
Mol Cell; 2012 Mar; 45(6):754-63. PubMed ID: 22464442
[TBL] [Abstract][Full Text] [Related]
10. Bortezomib induces apoptosis via Bim and Bik up-regulation and synergizes with cisplatin in the killing of head and neck squamous cell carcinoma cells.
Li C; Li R; Grandis JR; Johnson DE
Mol Cancer Ther; 2008 Jun; 7(6):1647-55. PubMed ID: 18566236
[TBL] [Abstract][Full Text] [Related]
11. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
Kuwana T; Bouchier-Hayes L; Chipuk JE; Bonzon C; Sullivan BA; Green DR; Newmeyer DD
Mol Cell; 2005 Feb; 17(4):525-35. PubMed ID: 15721256
[TBL] [Abstract][Full Text] [Related]
12. Single-agent obatoclax (GX15-070) potently induces apoptosis and pro-survival autophagy in head and neck squamous cell carcinoma cells.
Yazbeck VY; Li C; Grandis JR; Zang Y; Johnson DE
Oral Oncol; 2014 Feb; 50(2):120-7. PubMed ID: 24216166
[TBL] [Abstract][Full Text] [Related]
13. A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas.
Lee TL; Yeh J; Friedman J; Yan B; Yang X; Yeh NT; Van Waes C; Chen Z
Int J Cancer; 2008 May; 122(9):1987-98. PubMed ID: 18172861
[TBL] [Abstract][Full Text] [Related]
14. Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.
Uren RT; Dewson G; Chen L; Coyne SC; Huang DC; Adams JM; Kluck RM
J Cell Biol; 2007 Apr; 177(2):277-87. PubMed ID: 17452531
[TBL] [Abstract][Full Text] [Related]
15. Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis.
Rajan S; Choi M; Baek K; Yoon HS
Proteins; 2015 Jul; 83(7):1262-72. PubMed ID: 25907960
[TBL] [Abstract][Full Text] [Related]
16. Nuclear magnetic resonance study of protein-protein interactions involving apoptosis regulator Diva (Boo) and the BH3 domain of proapoptotic Bcl-2 members.
Santiveri CM; Sborgi L; de Alba E
J Mol Recognit; 2012 Dec; 25(12):665-73. PubMed ID: 23192964
[TBL] [Abstract][Full Text] [Related]
17. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.
Letai A; Bassik MC; Walensky LD; Sorcinelli MD; Weiler S; Korsmeyer SJ
Cancer Cell; 2002 Sep; 2(3):183-92. PubMed ID: 12242151
[TBL] [Abstract][Full Text] [Related]
18. Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins.
Moreau C; Cartron PF; Hunt A; Meflah K; Green DR; Evan G; Vallette FM; Juin P
J Biol Chem; 2003 May; 278(21):19426-35. PubMed ID: 12642586
[TBL] [Abstract][Full Text] [Related]
19. Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members.
Certo M; Del Gaizo Moore V; Nishino M; Wei G; Korsmeyer S; Armstrong SA; Letai A
Cancer Cell; 2006 May; 9(5):351-65. PubMed ID: 16697956
[TBL] [Abstract][Full Text] [Related]
20. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
Cheng EH; Wei MC; Weiler S; Flavell RA; Mak TW; Lindsten T; Korsmeyer SJ
Mol Cell; 2001 Sep; 8(3):705-11. PubMed ID: 11583631
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
