BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 17973264)

  • 21. DOXO-EMCH (INNO-206): the first albumin-binding prodrug of doxorubicin to enter clinical trials.
    Kratz F
    Expert Opin Investig Drugs; 2007 Jun; 16(6):855-66. PubMed ID: 17501697
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Evaluation of combination therapy schedules of doxorubicin and an acid-sensitive albumin-binding prodrug of doxorubicin in the MIA PaCa-2 pancreatic xenograft model.
    Kratz F; Azab S; Zeisig R; Fichtner I; Warnecke A
    Int J Pharm; 2013 Jan; 441(1-2):499-506. PubMed ID: 23149257
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A prostate-specific antigen (PSA)-activated vinblastine prodrug selectively kills PSA-secreting cells in vivo.
    DeFeo-Jones D; Brady SF; Feng DM; Wong BK; Bolyar T; Haskell K; Kiefer DM; Leander K; McAvoy E; Lumma P; Pawluczyk JM; Wai J; Motzel SL; Keenan K; Van Zwieten M; Lin JH; Garsky VM; Freidinger R; Oliff A; Jones RE
    Mol Cancer Ther; 2002 May; 1(7):451-9. PubMed ID: 12479263
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Zosuquidar and an albumin-binding prodrug of zosuquidar reverse multidrug resistance in breast cancer cells of doxorubicin and an albumin-binding prodrug of doxorubicin.
    Abu Ajaj K; Graeser R; Kratz F
    Breast Cancer Res Treat; 2012 Jul; 134(1):117-29. PubMed ID: 22228402
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A new approach for the treatment of malignant melanoma: enhanced antitumor efficacy of an albumin-binding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2.
    Mansour AM; Drevs J; Esser N; Hamada FM; Badary OA; Unger C; Fichtner I; Kratz F
    Cancer Res; 2003 Jul; 63(14):4062-6. PubMed ID: 12874007
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Targeted prodrug approaches for hormone refractory prostate cancer.
    Aloysius H; Hu L
    Med Res Rev; 2015 May; 35(3):554-85. PubMed ID: 25529338
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Encapsulation of doxorubicin prodrug in heat-triggered liposomes overcomes off-target activation for advanced prostate cancer therapy.
    Pereira S; Ma G; Na L; Hudoklin S; Kreft ME; Kostevsek N; Al-Jamal WT
    Acta Biomater; 2022 Mar; 140():530-546. PubMed ID: 34954416
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synergistic tumor growth-inhibitory effect of the prostate-specific antigen-activated fusion peptide BSD352 for prostate cancer therapy.
    Li B; Zhang LJ; Zhang ZL; Long M; Ren JH; Lin F; Wang X; Wei JX; Dong K; Zhang HZ
    Anticancer Drugs; 2011 Mar; 22(3):213-22. PubMed ID: 21150773
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Characterization of a novel prostate-specific antigen-activated peptide-doxorubicin conjugate in patients with prostate cancer.
    DiPaola RS; Rinehart J; Nemunaitis J; Ebbinghaus S; Rubin E; Capanna T; Ciardella M; Doyle-Lindrud S; Goodwin S; Fontaine M; Adams N; Williams A; Schwartz M; Winchell G; Wickersham K; Deutsch P; Yao SL
    J Clin Oncol; 2002 Apr; 20(7):1874-9. PubMed ID: 11919247
    [TBL] [Abstract][Full Text] [Related]  

  • 30. CD10 is a key enzyme involved in the activation of tumor-activated peptide prodrug CPI-0004Na and novel analogues: implications for the design of novel peptide prodrugs for the therapy of CD10+ tumors.
    Pan C; Cardarelli PM; Nieder MH; Pickford LB; Gangwar S; King DJ; Yarranton GT; Buckman D; Roscoe W; Zhou F; Salles A; Chen TH; Horgan K; Wang YH; Nguyen T; Bebbington CR
    Cancer Res; 2003 Sep; 63(17):5526-31. PubMed ID: 14500390
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Development of a novel albumin-binding prodrug that is cleaved by urokinase-type-plasminogen activator (uPA).
    Chung DE; Kratz F
    Bioorg Med Chem Lett; 2006 Oct; 16(19):5157-63. PubMed ID: 16875815
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Concentration of enzymatically active prostate-specific antigen (PSA) in the extracellular fluid of primary human prostate cancers and human prostate cancer xenograft models.
    Denmeade SR; Sokoll LJ; Chan DW; Khan SR; Isaacs JT
    Prostate; 2001 Jun; 48(1):1-6. PubMed ID: 11391681
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A prostate-specific antigen-activated channel-forming toxin as therapy for prostatic disease.
    Williams SA; Merchant RF; Garrett-Mayer E; Isaacs JT; Buckley JT; Denmeade SR
    J Natl Cancer Inst; 2007 Mar; 99(5):376-85. PubMed ID: 17341729
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Folate-targeted enzyme prodrug cancer therapy utilizing penicillin-V amidase and a doxorubicin prodrug.
    Lu JY; Lowe DA; Kennedy MD; Low PS
    J Drug Target; 1999; 7(1):43-53. PubMed ID: 10614814
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Doxorubicin/heparin composite nanoparticles for caspase-activated prodrug chemotherapy.
    Khaliq NU; Sandra FC; Park DY; Lee JY; Oh KS; Kim D; Byun Y; Kim IS; Kwon IC; Kim SY; Yuk SH
    Biomaterials; 2016 Sep; 101():131-42. PubMed ID: 27286189
    [TBL] [Abstract][Full Text] [Related]  

  • 36. In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)2] that targets integrin alphavbeta3.
    Ryppa C; Mann-Steinberg H; Fichtner I; Weber H; Satchi-Fainaro R; Biniossek ML; Kratz F
    Bioconjug Chem; 2008 Jul; 19(7):1414-22. PubMed ID: 18578486
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Screening for new peptide substrates for the development of albumin binding anticancer pro-drugs that are cleaved by prostate-specific antigen (PSA) to improve the anti tumor efficacy.
    Elsadek BEM; Hassan MH
    Biochem Biophys Rep; 2021 Jul; 26():100966. PubMed ID: 33718631
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Iterative design of emetine-based prodrug targeting fibroblast activation protein (FAP) and dipeptidyl peptidase IV DPPIV using a tandem enzymatic activation strategy.
    Akinboye ES; Brennen WN; Rosen DM; Bakare O; Denmeade SR
    Prostate; 2016 Jun; 76(8):703-14. PubMed ID: 26835873
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Synthesis and antitumor efficacy of a β-glucuronidase-responsive albumin-binding prodrug of doxorubicin.
    Legigan T; Clarhaut J; Renoux B; Tranoy-Opalinski I; Monvoisin A; Berjeaud JM; Guilhot F; Papot S
    J Med Chem; 2012 May; 55(9):4516-20. PubMed ID: 22515366
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody beta-glucuronidase conjugate.
    Houba PH; Boven E; van der Meulen-Muileman IH; Leenders RG; Scheeren JW; Pinedo HM; Haisma HJ
    Int J Cancer; 2001 Feb; 91(4):550-4. PubMed ID: 11251980
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.