BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 17973471)

  • 1. Multiple N-methylation by a designed approach enhances receptor selectivity.
    Chatterjee J; Ovadia O; Zahn G; Marinelli L; Hoffman A; Gilon C; Kessler H
    J Med Chem; 2007 Nov; 50(24):5878-81. PubMed ID: 17973471
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and synthesis of a new class of selective integrin alpha5beta1 antagonists.
    Stragies R; Osterkamp F; Zischinsky G; Vossmeyer D; Kalkhof H; Reimer U; Zahn G
    J Med Chem; 2007 Aug; 50(16):3786-94. PubMed ID: 17616113
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Probing integrin selectivity: rational design of highly active and selective ligands for the alpha5beta1 and alphavbeta3 integrin receptor.
    Heckmann D; Meyer A; Marinelli L; Zahn G; Stragies R; Kessler H
    Angew Chem Int Ed Engl; 2007; 46(19):3571-4. PubMed ID: 17394271
    [No Abstract]   [Full Text] [Related]  

  • 4. Antiangiogenic effect of dual/selective alpha(5)beta(1)/alpha(v)beta(3) integrin antagonists designed on partially modified retro-inverso cyclotetrapeptide mimetics.
    Gentilucci L; Cardillo G; Spampinato S; Tolomelli A; Squassabia F; De Marco R; Bedini A; Baiula M; Belvisi L; Civera M
    J Med Chem; 2010 Jan; 53(1):106-18. PubMed ID: 20055426
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rational design of highly active and selective ligands for the alpha5beta1 integrin receptor.
    Heckmann D; Meyer A; Laufer B; Zahn G; Stragies R; Kessler H
    Chembiochem; 2008 Jun; 9(9):1397-407. PubMed ID: 18481343
    [TBL] [Abstract][Full Text] [Related]  

  • 6. N-methylation of peptides: a new perspective in medicinal chemistry.
    Chatterjee J; Gilon C; Hoffman A; Kessler H
    Acc Chem Res; 2008 Oct; 41(10):1331-42. PubMed ID: 18636716
    [TBL] [Abstract][Full Text] [Related]  

  • 7. N-Aryl-gamma-lactams as integrin alphavbeta3 antagonists.
    Xi N; Arvedson S; Eisenberg S; Han N; Handley M; Huang L; Huang Q; Kiselyov A; Liu Q; Lu Y; Nunez G; Osslund T; Powers D; Tasker AS; Wang L; Xiang T; Xu S; Zhang J; Zhu J; Kendall R; Dominguez C
    Bioorg Med Chem Lett; 2004 Jun; 14(11):2905-9. PubMed ID: 15125957
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metadynamics Simulations Rationalise the Conformational Effects Induced by N-Methylation of RGD Cyclic Hexapeptides.
    Paissoni C; Ghitti M; Belvisi L; Spitaleri A; Musco G
    Chemistry; 2015 Sep; 21(40):14165-70. PubMed ID: 26248541
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mass spectrometric based mapping of the disulfide bonding patterns of integrin alpha chains.
    Krokhin OV; Cheng K; Sousa SL; Ens W; Standing KG; Wilkins JA
    Biochemistry; 2003 Nov; 42(44):12950-9. PubMed ID: 14596610
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biselectivity of isoDGR peptides for fibronectin binding integrin subtypes α5β1 and αvβ6: conformational control through flanking amino acids.
    Bochen A; Marelli UK; Otto E; Pallarola D; Mas-Moruno C; Di Leva FS; Boehm H; Spatz JP; Novellino E; Kessler H; Marinelli L
    J Med Chem; 2013 Feb; 56(4):1509-19. PubMed ID: 23362923
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Therapeutic integrin inhibition: allosteric and activation-specific inhibition strategies may surpass the initial ligand-mimetic strategies.
    Ahrens I; Peter K
    Thromb Haemost; 2008 May; 99(5):803-4. PubMed ID: 18449408
    [No Abstract]   [Full Text] [Related]  

  • 12. The constrained amino acid beta-Acc confers potency and selectivity to integrin ligands.
    Urman S; Gaus K; Yang Y; Strijowski U; Sewald N; De Pol S; Reiser O
    Angew Chem Int Ed Engl; 2007; 46(21):3976-8. PubMed ID: 17394270
    [No Abstract]   [Full Text] [Related]  

  • 13. N-methylated cyclic pentaalanine peptides as template structures.
    Chatterjee J; Mierke D; Kessler H
    J Am Chem Soc; 2006 Nov; 128(47):15164-72. PubMed ID: 17117868
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cyclic isoDGR peptidomimetics as low-nanomolar αvβ3 integrin ligands.
    Mingozzi M; Dal Corso A; Marchini M; Guzzetti I; Civera M; Piarulli U; Arosio D; Belvisi L; Potenza D; Pignataro L; Gennari C
    Chemistry; 2013 Mar; 19(11):3563-7. PubMed ID: 23424096
    [No Abstract]   [Full Text] [Related]  

  • 15. The disintegrin echistatin stabilizes integrin alphaIIbbeta3's open conformation and promotes its oligomerization.
    Hantgan RR; Stahle MC; Connor JH; Lyles DS; Horita DA; Rocco M; Nagaswami C; Weisel JW; McLane MA
    J Mol Biol; 2004 Oct; 342(5):1625-36. PubMed ID: 15364586
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of novel short chain 4-substituted indoles as potent alphavbeta3 antagonist using structure-based drug design.
    Raboisson P; Desjarlais RL; Reed R; Lattanze J; Chaikin M; Manthey CL; Tomczuk BE; Marugán JJ
    Eur J Med Chem; 2007 Mar; 42(3):334-43. PubMed ID: 17184884
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of diketopiperazines with on-resin N-methylation and cyclative release.
    Brunel FM; Spatola AF
    J Pept Res; 2004 Mar; 63(3):213-22. PubMed ID: 15049833
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increasing αvβ3 selectivity of the anti-angiogenic drug cilengitide by N-methylation.
    Mas-Moruno C; Beck JG; Doedens L; Frank AO; Marinelli L; Cosconati S; Novellino E; Kessler H
    Angew Chem Int Ed Engl; 2011 Sep; 50(40):9496-500. PubMed ID: 21948451
    [No Abstract]   [Full Text] [Related]  

  • 19. Contribution of distinct platelet integrins to binding, unfolding, and assembly of fibronectin.
    Huynh KC; Stoldt VR; Scharf RE
    Biol Chem; 2013 Nov; 394(11):1485-93. PubMed ID: 23929882
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tricyclic pharmacophore-based molecules as novel integrin alphavbeta3 antagonists. Part IV: preliminary control of alphavbeta3 selectivity by meta-oriented substitution.
    Kubota D; Ishikawa M; Ishikawa M; Yahata N; Murakami S; Fujishima K; Kitakaze M; Ajito K
    Bioorg Med Chem; 2006 Jun; 14(12):4158-81. PubMed ID: 16504518
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.