BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 17975002)

  • 1. TSC2 loss in lymphangioleiomyomatosis cells correlated with expression of CD44v6, a molecular determinant of metastasis.
    Pacheco-Rodriguez G; Steagall WK; Crooks DM; Stevens LA; Hashimoto H; Li S; Wang JA; Darling TN; Moss J
    Cancer Res; 2007 Nov; 67(21):10573-81. PubMed ID: 17975002
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Circulating Lymphangioleiomyomatosis Tumor Cells With Loss of Heterozygosity in the TSC2 Gene Show Increased Aldehyde Dehydrogenase Activity.
    Pacheco-Rodríguez G; Steagall WK; Samsel L; Dagur PK; McCoy JP; Tunc I; Pirooznia M; Wang JA; Darling TN; Moss J
    Chest; 2019 Aug; 156(2):298-307. PubMed ID: 31034819
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phenotypic characterization of disseminated cells with TSC2 loss of heterozygosity in patients with lymphangioleiomyomatosis.
    Cai X; Pacheco-Rodriguez G; Fan QY; Haughey M; Samsel L; El-Chemaly S; Wu HP; McCoy JP; Steagall WK; Lin JP; Darling TN; Moss J
    Am J Respir Crit Care Med; 2010 Dec; 182(11):1410-8. PubMed ID: 20639436
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Osteoprotegerin contributes to the metastatic potential of cells with a dysfunctional TSC2 tumor-suppressor gene.
    Steagall WK; Pacheco-Rodriguez G; Glasgow CG; Ikeda Y; Lin JP; Zheng G; Moss J
    Am J Pathol; 2013 Sep; 183(3):938-50. PubMed ID: 23867796
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene.
    Pacheco-Rodriguez G; Kumaki F; Steagall WK; Zhang Y; Ikeda Y; Lin JP; Billings EM; Moss J
    J Immunol; 2009 Feb; 182(3):1270-7. PubMed ID: 19155472
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pulmonary Langerhans Cell Histiocytosis and Lymphangioleiomyomatosis Have Circulating Cells With Loss of Heterozygosity of the TSC2 Gene.
    Elia D; Torre O; Vasco C; Geginat J; Abrignani S; Bulgheroni E; Carelli E; Cassandro R; Pacheco-Rodriguez G; Steagall WK; Moss J; Harari S
    Chest; 2022 Aug; 162(2):385-393. PubMed ID: 35231481
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sirolimus decreases circulating lymphangioleiomyomatosis cells in patients with lymphangioleiomyomatosis.
    Cai X; Pacheco-Rodriguez G; Haughey M; Samsel L; Xu S; Wu HP; McCoy JP; Stylianou M; Darling TN; Moss J
    Chest; 2014 Jan; 145(1):108-112. PubMed ID: 24051985
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Clinical and molecular insights into lymphangioleiomyomatosis.
    Steagall WK; Taveira-DaSilva AM; Moss J
    Sarcoidosis Vasc Diffuse Lung Dis; 2005 Dec; 22 Suppl 1():S49-66. PubMed ID: 16457017
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TSC2 epigenetic defect in primary LAM cells. Evidence of an anchorage-independent survival.
    Lesma E; Ancona S; Sirchia SM; Orpianesi E; Grande V; Colapietro P; Chiaramonte E; Di Giulio AM; Gorio A
    J Cell Mol Med; 2014 May; 18(5):766-79. PubMed ID: 24606538
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of chemokines in migration of metastatic-like lymphangioleiomyomatosis cells.
    Pacheco-Rodriguez G; Moss J
    Crit Rev Immunol; 2010; 30(4):387-94. PubMed ID: 20666708
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence that lymphangiomyomatosis is caused by TSC2 mutations: chromosome 16p13 loss of heterozygosity in angiomyolipomas and lymph nodes from women with lymphangiomyomatosis.
    Smolarek TA; Wessner LL; McCormack FX; Mylet JC; Menon AG; Henske EP
    Am J Hum Genet; 1998 Apr; 62(4):810-5. PubMed ID: 9529362
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Progesterone and estradiol synergistically promote the lung metastasis of tuberin-deficient cells in a preclinical model of lymphangioleiomyomatosis.
    Sun Y; Zhang E; Lao T; Pereira AM; Li C; Xiong L; Morrison T; Haley KJ; Zhou X; Yu JJ
    Horm Cancer; 2014 Oct; 5(5):284-98. PubMed ID: 25069840
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation.
    Goncharova EA; Goncharov DA; Chisolm A; Spaits MS; Lim PN; Cesarone G; Khavin I; Tliba O; Amrani Y; Panettieri RA; Krymskaya VP
    Mol Pharmacol; 2008 Mar; 73(3):778-88. PubMed ID: 18094073
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Detection of low-prevalence somatic TSC2 mutations in sporadic pulmonary lymphangioleiomyomatosis tissues by deep sequencing.
    Fujita A; Ando K; Kobayashi E; Mitani K; Okudera K; Nakashima M; Miyatake S; Tsurusaki Y; Saitsu H; Seyama K; Miyake N; Matsumoto N
    Hum Genet; 2016 Jan; 135(1):61-8. PubMed ID: 26563443
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors.
    Stepanova V; Dergilev KV; Holman KR; Parfyonova YV; Tsokolaeva ZI; Teter M; Atochina-Vasserman EN; Volgina A; Zaitsev SV; Lewis SP; Zabozlaev FG; Obraztsova K; Krymskaya VP; Cines DB
    J Biol Chem; 2017 Dec; 292(50):20528-20543. PubMed ID: 28972182
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oncogenic effects of urotensin-II in cells lacking tuberous sclerosis complex-2.
    Goldberg AA; Joung KB; Mansuri A; Kang Y; Echavarria R; Nikolajev L; Sun Y; Yu JJ; Laporte SA; Schwertani A; Kristof AS
    Oncotarget; 2016 Sep; 7(38):61152-61165. PubMed ID: 27458154
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis.
    Sato T; Seyama K; Fujii H; Maruyama H; Setoguchi Y; Iwakami S; Fukuchi Y; Hino O
    J Hum Genet; 2002; 47(1):20-8. PubMed ID: 11829138
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Estrogen maintains myometrial tumors in a lymphangioleiomyomatosis model.
    Prizant H; Taya M; Lerman I; Light A; Sen A; Mitra S; Foster TH; Hammes SR
    Endocr Relat Cancer; 2016 Apr; 23(4):265-80. PubMed ID: 26880751
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rapamycin-insensitive up-regulation of adipocyte phospholipase A2 in tuberous sclerosis and lymphangioleiomyomatosis.
    Li C; Zhang E; Sun Y; Lee PS; Zhan Y; Guo Y; Osorio JC; Rosas IO; Xu KF; Kwiatkowski DJ; Yu JJ
    PLoS One; 2014; 9(10):e104809. PubMed ID: 25347447
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular and genetic analysis of disseminated neoplastic cells in lymphangioleiomyomatosis.
    Crooks DM; Pacheco-Rodriguez G; DeCastro RM; McCoy JP; Wang JA; Kumaki F; Darling T; Moss J
    Proc Natl Acad Sci U S A; 2004 Dec; 101(50):17462-7. PubMed ID: 15583138
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.