BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 17975887)

  • 1. Metabolic profiling of endocrine-disrupting compounds by on-line cytochrome p450 bioreaction coupled to on-line receptor affinity screening.
    Van Liempd SM; Kool J; Meerman JH; Irth H; Vermeulen NP
    Chem Res Toxicol; 2007 Dec; 20(12):1825-32. PubMed ID: 17975887
    [TBL] [Abstract][Full Text] [Related]  

  • 2. On-line formation, separation, and estrogen receptor affinity screening of cytochrome P450-derived metabolites of selective estrogen receptor modulators.
    van Liempd SM; Kool J; Niessen WM; van Elswijk DE; Irth H; Vermeulen NP
    Drug Metab Dispos; 2006 Sep; 34(9):1640-9. PubMed ID: 16790557
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of a novel cytochrome p450 bioaffinity detection system coupled online to gradient reversed-phase high-performance liquid chromatography.
    Kool J; van Liempd SM; Ramautar R; Schenk T; Meerman JH; Irth H; Commandeur JN; Vermeulen NP
    J Biomol Screen; 2005 Aug; 10(5):427-36. PubMed ID: 16093552
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Application of cytochrome P450 BM3 mutants as biocatalysts for the profiling of estrogen receptor binding metabolites of the mycotoxin zearalenone.
    Reinen J; Kalma LL; Begheijn S; Heus F; Commandeur JN; Vermeulen NP
    Xenobiotica; 2011 Jan; 41(1):59-70. PubMed ID: 21087115
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of three parallel cytochrome P450 enzyme affinity detection systems coupled on-line to gradient high-performance liquid chromatography.
    Kool J; van Liempd SM; van Rossum H; van Elswijk DA; Irth H; Commandeur JN; Vermeulen NP
    Drug Metab Dispos; 2007 Apr; 35(4):640-8. PubMed ID: 17251308
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rapid on-line profiling of estrogen receptor binding metabolites of tamoxifen.
    Kool J; Ramautar R; van Liempd SM; Beckman J; de Kanter FJ; Meerman JH; Schenk T; Irth H; Commandeur JN; Vermeulen NP
    J Med Chem; 2006 Jun; 49(11):3287-92. PubMed ID: 16722647
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Quantifying phthalate metabolites in human meconium and semen using automated off-line solid-phase extraction coupled with on-line SPE and isotope-dilution high-performance liquid chromatography--tandem mass spectrometry.
    Kato K; Silva MJ; Needham LL; Calafat AM
    Anal Chem; 2006 Sep; 78(18):6651-5. PubMed ID: 16970347
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Automated on-line column-switching HPLC-MS/MS method with peak focusing for the determination of nine environmental phenols in urine.
    Ye X; Kuklenyik Z; Needham LL; Calafat AM
    Anal Chem; 2005 Aug; 77(16):5407-13. PubMed ID: 16097788
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Determination and identification of estrogenic compounds generated with biosynthetic enzymes using hyphenated screening assays, high resolution mass spectrometry and off-line NMR.
    de Vlieger JS; Kolkman AJ; Ampt KA; Commandeur JN; Vermeulen NP; Kool J; Wijmenga SS; Niessen WM; Irth H; Honing M
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 Mar; 878(7-8):667-74. PubMed ID: 20149764
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolic screening using on-line ultrafiltration mass spectrometry.
    van Breemen RB; Nikolic D; Bolton JL
    Drug Metab Dispos; 1998 Feb; 26(2):85-90. PubMed ID: 9456292
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Demethylation of the pesticide methoxychlor in liver and intestine from untreated, methoxychlor-treated, and 3-methylcholanthrene-treated channel catfish (Ictalurus punctatus): evidence for roles of CYP1 and CYP3A family isozymes.
    Stuchal LD; Kleinow KM; Stegeman JJ; James MO
    Drug Metab Dispos; 2006 Jun; 34(6):932-8. PubMed ID: 16510540
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro cytochrome P450 activity: development and validation of a sensitive high performance liquid chromatography-tandem mass spectrometry method for the quantification of six probe metabolites after derivatization with pyridine-3-sulfonyl chloride in an aqueous environment.
    De Bock L; Vande Casteele SR; Mulliez SM; Boussery K; Van Bocxlaer JF
    J Chromatogr A; 2011 Feb; 1218(6):793-801. PubMed ID: 21194699
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High performance liquid chromatography-tandem mass spectrometry for the analysis of 10 pesticides in water: a comparison between membrane-assisted solvent extraction and solid phase extraction.
    van Pinxteren M; Bauer C; Popp P
    J Chromatogr A; 2009 Jul; 1216(31):5800-6. PubMed ID: 19570541
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Influence of beta-naphthoflavone and methoxychlor pretreatment on the biotransformation and estrogenic activity of methoxychlor in channel catfish (Ictalurus punctatus).
    Schlenk D; Stresser DM; McCants JC; Nimrod AC; Benson WH
    Toxicol Appl Pharmacol; 1997 Aug; 145(2):349-56. PubMed ID: 9266808
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of methoxychlor and estradiol on cytochrome p450 enzymes in the mouse ovarian surface epithelium.
    Symonds DA; Miller KP; Tomic D; Flaws JA
    Toxicol Sci; 2006 Feb; 89(2):510-4. PubMed ID: 16280380
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sub one minute inhibition assays for the major cytochrome P450 enzymes utilizing ultra-performance liquid chromatography/tandem mass spectrometry.
    Rainville PD; Wheaton JP; Alden PG; Plumb RS
    Rapid Commun Mass Spectrom; 2008 May; 22(9):1345-50. PubMed ID: 18381621
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Screening of protein-ligand interactions using dynamic protein-affinity chromatography solid-phase extraction-liquid chromatography-mass spectrometry.
    Jonker N; Kool J; Krabbe JG; Retra K; Lingeman H; Irth H
    J Chromatogr A; 2008 Sep; 1205(1-2):71-7. PubMed ID: 18715568
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Urinary 5-HIAA measurement using automated on-line solid-phase extraction-high-performance liquid chromatography-tandem mass spectrometry.
    de Jong WH; Graham KS; de Vries EG; Kema IP
    J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Jun; 868(1-2):28-33. PubMed ID: 18482877
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chip-based P450 drug metabolism coupled to electrospray ionization-mass spectrometry detection.
    Benetton S; Kameoka J; Tan A; Wachs T; Craighead H; Henion JD
    Anal Chem; 2003 Dec; 75(23):6430-6. PubMed ID: 14640711
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s.
    Wen B; Ma L; Zhu M
    Chem Biol Interact; 2008 May; 173(1):59-67. PubMed ID: 18359012
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.