266 related articles for article (PubMed ID: 17977725)
21. On the Reversible and Irreversible Inhibition of Rhodesain by Curcumin.
Steverding D
Molecules; 2019 Dec; 25(1):. PubMed ID: 31905815
[TBL] [Abstract][Full Text] [Related]
22. Antitrypanosomal and cysteine protease inhibitory activities of alkyldiamine cryptolepine derivatives.
Lavrado J; Mackey Z; Hansell E; McKerrow JH; Paulo A; Moreira R
Bioorg Med Chem Lett; 2012 Oct; 22(19):6256-60. PubMed ID: 22926067
[TBL] [Abstract][Full Text] [Related]
23. Synthesis of macrocyclic trypanosomal cysteine protease inhibitors.
Chen YT; Lira R; Hansell E; McKerrow JH; Roush WR
Bioorg Med Chem Lett; 2008 Nov; 18(22):5860-3. PubMed ID: 18585034
[TBL] [Abstract][Full Text] [Related]
24. Dipeptidyl aspartyl fluoromethylketones as potent caspase inhibitors: peptidomimetic replacement of the P2 alpha-amino acid by a alpha-hydroxy acid.
Wang Y; Guan L; Jia S; Tseng B; Drewe J; Cai SX
Bioorg Med Chem Lett; 2005 Mar; 15(5):1379-83. PubMed ID: 15713391
[TBL] [Abstract][Full Text] [Related]
25. Synthesis and structure-activity relationship studies of cruzain and rhodesain inhibitors.
Rocha DA; Silva EB; Fortes IS; Lopes MS; Ferreira RS; Andrade SF
Eur J Med Chem; 2018 Sep; 157():1426-1459. PubMed ID: 30282318
[TBL] [Abstract][Full Text] [Related]
26. Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors.
Micale N; Ettari R; Schirmeister T; Evers A; Gelhaus C; Leippe M; Zappalà M; Grasso S
Bioorg Med Chem; 2009 Sep; 17(18):6505-11. PubMed ID: 19709887
[TBL] [Abstract][Full Text] [Related]
27. Structure-Based Optimization of Quinazolines as Cruzain and
Barbosa da Silva E; Rocha DA; Fortes IS; Yang W; Monti L; Siqueira-Neto JL; Caffrey CR; McKerrow J; Andrade SF; Ferreira RS
J Med Chem; 2021 Sep; 64(17):13054-13071. PubMed ID: 34461718
[TBL] [Abstract][Full Text] [Related]
28. Synthesis and biological evaluation of reversible inhibitors of IdeS, a bacterial cysteine protease and virulence determinant.
Berggren K; Johansson B; Fex T; Kihlberg J; Björck L; Luthman K
Bioorg Med Chem; 2009 May; 17(9):3463-70. PubMed ID: 19362485
[TBL] [Abstract][Full Text] [Related]
29. Development of rhodesain inhibitors with a 3-bromoisoxazoline warhead.
Ettari R; Tamborini L; Angelo IC; Grasso S; Schirmeister T; Lo Presti L; De Micheli C; Pinto A; Conti P
ChemMedChem; 2013 Dec; 8(12):2070-6. PubMed ID: 24243827
[TBL] [Abstract][Full Text] [Related]
30. Cysteine proteinase inhibitors kill cultured bloodstream forms of Trypanosoma brucei brucei.
Troeberg L; Morty RE; Pike RN; Lonsdale-Eccles JD; Palmer JT; McKerrow JH; Coetzer TH
Exp Parasitol; 1999 Apr; 91(4):349-55. PubMed ID: 10092479
[TBL] [Abstract][Full Text] [Related]
31. Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB.
Mallari JP; Shelat A; Kosinski A; Caffrey CR; Connelly M; Zhu F; McKerrow JH; Guy RK
Bioorg Med Chem Lett; 2008 May; 18(9):2883-5. PubMed ID: 18420405
[TBL] [Abstract][Full Text] [Related]
32. Discovery and characterization of trypanocidal cysteine protease inhibitors from the 'malaria box'.
Pereira GAN; da Silva EB; Braga SFP; Leite PG; Martins LC; Vieira RP; Soh WT; Villela FS; Costa FMR; Ray D; de Andrade SF; Brandstetter H; Oliveira RB; Caffrey CR; Machado FS; Ferreira RS
Eur J Med Chem; 2019 Oct; 179():765-778. PubMed ID: 31284086
[TBL] [Abstract][Full Text] [Related]
33. Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics.
Dragovich PS; Prins TJ; Zhou R; Fuhrman SA; Patick AK; Matthews DA; Ford CE; Meador JW; Ferre RA; Worland ST
J Med Chem; 1999 Apr; 42(7):1203-12. PubMed ID: 10197964
[TBL] [Abstract][Full Text] [Related]
34. Naphthoquinones as Covalent Reversible Inhibitors of Cysteine Proteases-Studies on Inhibition Mechanism and Kinetics.
Klein P; Barthels F; Johe P; Wagner A; Tenzer S; Distler U; Le TA; Schmid P; Engel V; Engels B; Hellmich UA; Opatz T; Schirmeister T
Molecules; 2020 Apr; 25(9):. PubMed ID: 32354191
[TBL] [Abstract][Full Text] [Related]
35. Solid-phase methods for the preparation of epoxysuccinate-based inhibitors of cysteine proteases.
Sadaghiani AM; Verhelst SH; Bogyo M
J Comb Chem; 2006; 8(6):802-4. PubMed ID: 17096566
[No Abstract] [Full Text] [Related]
36. Azadipeptide nitriles: highly potent and proteolytically stable inhibitors of papain-like cysteine proteases.
Löser R; Frizler M; Schilling K; Gütschow M
Angew Chem Int Ed Engl; 2008; 47(23):4331-4. PubMed ID: 18404765
[No Abstract] [Full Text] [Related]
37. Aziridine-2,3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents.
Vicik R; Hoerr V; Glaser M; Schultheis M; Hansell E; McKerrow JH; Holzgrabe U; Caffrey CR; Ponte-Sucre A; Moll H; Stich A; Schirmeister T
Bioorg Med Chem Lett; 2006 May; 16(10):2753-7. PubMed ID: 16516467
[TBL] [Abstract][Full Text] [Related]
38. 2D QSAR and similarity studies on cruzain inhibitors aimed at improving selectivity over cathepsin L.
Freitas RF; Oprea TI; Montanari CA
Bioorg Med Chem; 2008 Jan; 16(2):838-53. PubMed ID: 17996450
[TBL] [Abstract][Full Text] [Related]
39. Vinyl sulfone-based inhibitors of trypanosomal cysteine protease rhodesain with improved antitrypanosomal activities.
Zhang H; Collins J; Nyamwihura R; Crown O; Ajayi O; Ogungbe IV
Bioorg Med Chem Lett; 2020 Jul; 30(14):127217. PubMed ID: 32527539
[TBL] [Abstract][Full Text] [Related]
40. Potency and selectivity of P2/P3-modified inhibitors of cysteine proteases from trypanosomes.
Jaishankar P; Hansell E; Zhao DM; Doyle PS; McKerrow JH; Renslo AR
Bioorg Med Chem Lett; 2008 Jan; 18(2):624-8. PubMed ID: 18055204
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
