179 related articles for article (PubMed ID: 17977838)
1. Novel roles in human MD-2 of phenylalanines 121 and 126 and tyrosine 131 in activation of Toll-like receptor 4 by endotoxin.
Teghanemt A; Re F; Prohinar P; Widstrom R; Gioannini TL; Weiss JP
J Biol Chem; 2008 Jan; 283(3):1257-1266. PubMed ID: 17977838
[TBL] [Abstract][Full Text] [Related]
2. Isolation of monomeric and dimeric secreted MD-2. Endotoxin.sCD14 and Toll-like receptor 4 ectodomain selectively react with the monomeric form of secreted MD-2.
Teghanemt A; Widstrom RL; Gioannini TL; Weiss JP
J Biol Chem; 2008 Aug; 283(32):21881-9. PubMed ID: 18519568
[TBL] [Abstract][Full Text] [Related]
3. Specific high affinity interactions of monomeric endotoxin.protein complexes with Toll-like receptor 4 ectodomain.
Prohinar P; Re F; Widstrom R; Zhang D; Teghanemt A; Weiss JP; Gioannini TL
J Biol Chem; 2007 Jan; 282(2):1010-7. PubMed ID: 17121827
[TBL] [Abstract][Full Text] [Related]
4. Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxin.
Resman N; Vasl J; Oblak A; Pristovsek P; Gioannini TL; Weiss JP; Jerala R
J Biol Chem; 2009 May; 284(22):15052-60. PubMed ID: 19321453
[TBL] [Abstract][Full Text] [Related]
5. Transfer of monomeric endotoxin from MD-2 to CD14: characterization and functional consequences.
Teghanemt A; Prohinar P; Gioannini TL; Weiss JP
J Biol Chem; 2007 Dec; 282(50):36250-6. PubMed ID: 17934216
[TBL] [Abstract][Full Text] [Related]
6. Endotoxin{middle dot}albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4.
Esparza GA; Teghanemt A; Zhang D; Gioannini TL; Weiss JP
Innate Immun; 2012 Jun; 18(3):478-91. PubMed ID: 21994253
[TBL] [Abstract][Full Text] [Related]
7. NMR studies of hexaacylated endotoxin bound to wild-type and F126A mutant MD-2 and MD-2·TLR4 ectodomain complexes.
Yu L; Phillips RL; Zhang D; Teghanemt A; Weiss JP; Gioannini TL
J Biol Chem; 2012 May; 287(20):16346-55. PubMed ID: 22433852
[TBL] [Abstract][Full Text] [Related]
8. Evidence of a specific interaction between new synthetic antisepsis agents and CD14.
Piazza M; Yu L; Teghanemt A; Gioannini T; Weiss J; Peri F
Biochemistry; 2009 Dec; 48(51):12337-44. PubMed ID: 19928913
[TBL] [Abstract][Full Text] [Related]
9. A Thermodynamic Funnel Drives Bacterial Lipopolysaccharide Transfer in the TLR4 Pathway.
Huber RG; Berglund NA; Kargas V; Marzinek JK; Holdbrook DA; Khalid S; Piggot TJ; Schmidtchen A; Bond PJ
Structure; 2018 Aug; 26(8):1151-1161.e4. PubMed ID: 29779787
[TBL] [Abstract][Full Text] [Related]
10. Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.
Visintin A; Halmen KA; Latz E; Monks BG; Golenbock DT
J Immunol; 2005 Nov; 175(10):6465-72. PubMed ID: 16272300
[TBL] [Abstract][Full Text] [Related]
11. Endotoxin-binding proteins modulate the susceptibility of bacterial endotoxin to deacylation by acyloxyacyl hydrolase.
Gioannini TL; Teghanemt A; Zhang D; Prohinar P; Levis EN; Munford RS; Weiss JP
J Biol Chem; 2007 Mar; 282(11):7877-84. PubMed ID: 17227775
[TBL] [Abstract][Full Text] [Related]
12. Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations.
Gioannini TL; Teghanemt A; Zhang D; Coussens NP; Dockstader W; Ramaswamy S; Weiss JP
Proc Natl Acad Sci U S A; 2004 Mar; 101(12):4186-91. PubMed ID: 15010525
[TBL] [Abstract][Full Text] [Related]
13. Novel roles of lysines 122, 125, and 58 in functional differences between human and murine MD-2.
Vasl J; Oblak A; Gioannini TL; Weiss JP; Jerala R
J Immunol; 2009 Oct; 183(8):5138-45. PubMed ID: 19783674
[TBL] [Abstract][Full Text] [Related]
14. Hemin and a metabolic derivative coprohemin modulate the TLR4 pathway differently through different molecular targets.
Piazza M; Damore G; Costa B; Gioannini TL; Weiss JP; Peri F
Innate Immun; 2011 Feb; 17(3):293-301. PubMed ID: 20472612
[TBL] [Abstract][Full Text] [Related]
15. Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling.
Rallabhandi P; Bell J; Boukhvalova MS; Medvedev A; Lorenz E; Arditi M; Hemming VG; Blanco JC; Segal DM; Vogel SN
J Immunol; 2006 Jul; 177(1):322-32. PubMed ID: 16785528
[TBL] [Abstract][Full Text] [Related]
16. Species-specific activation of TLR4 by hypoacylated endotoxins governed by residues 82 and 122 of MD-2.
Oblak A; Jerala R
PLoS One; 2014; 9(9):e107520. PubMed ID: 25203747
[TBL] [Abstract][Full Text] [Related]
17. Neisseria meningitidis lipooligosaccharide structure-dependent activation of the macrophage CD14/Toll-like receptor 4 pathway.
Zughaier SM; Tzeng YL; Zimmer SM; Datta A; Carlson RW; Stephens DS
Infect Immun; 2004 Jan; 72(1):371-80. PubMed ID: 14688118
[TBL] [Abstract][Full Text] [Related]
18. Monomeric endotoxin:protein complexes are essential for TLR4-dependent cell activation.
Gioannini TL; Teghanemt A; Zhang D; Levis EN; Weiss JP
J Endotoxin Res; 2005; 11(2):117-23. PubMed ID: 15949139
[TBL] [Abstract][Full Text] [Related]
19. Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
Visintin A; Latz E; Monks BG; Espevik T; Golenbock DT
J Biol Chem; 2003 Nov; 278(48):48313-20. PubMed ID: 12960171
[TBL] [Abstract][Full Text] [Related]
20. The cationic amphiphile 3,4-bis(tetradecyloxy)benzylamine inhibits LPS signaling by competing with endotoxin for CD14 binding.
Piazza M; Calabrese V; Baruffa C; Gioannini T; Weiss J; Peri F
Biochem Pharmacol; 2010 Dec; 80(12):2050-6. PubMed ID: 20599783
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
