BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 17978482)

  • 21. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.
    Rhodes SP; Otten JN; Hingorani GP; Hartley DP; Franklin RB
    J Pharmacol Toxicol Methods; 2011; 63(3):223-6. PubMed ID: 21111054
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Quantitative analysis of constitutive and inducible CYPs mRNA expression in the HepG2 cell line using reverse transcription-competitive PCR.
    Sumida A; Fukuen S; Yamamoto I; Matsuda H; Naohara M; Azuma J
    Biochem Biophys Res Commun; 2000 Jan; 267(3):756-60. PubMed ID: 10673364
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Ethnic differences between Japanese and Caucasians in the expression levels of mRNAs for CYP3A4, CYP3A5 and CYP3A7: lack of co-regulation of the expression of CYP3A in Japanese livers.
    Yamaori S; Yamazaki H; Iwano S; Kiyotani K; Matsumura K; Saito T; Parkinson A; Nakagawa K; Kamataki T
    Xenobiotica; 2005 Jan; 35(1):69-83. PubMed ID: 15788369
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Effects of hypoxia-inducible factor-1α chemical stabilizer, CoCl(2) and hypoxia on gene expression of CYP3As in human fetal liver cells.
    Suzuki E; Matsunaga T; Aonuma A; Sasaki T; Nagata K; Ohmori S
    Drug Metab Pharmacokinet; 2012; 27(4):398-404. PubMed ID: 22277676
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Cytochrome P450 3A expression in the human fetal liver: evidence that CYP3A5 is expressed in only a limited number of fetal livers.
    Hakkola J; Raunio H; Purkunen R; Saarikoski S; Vähäkangas K; Pelkonen O; Edwards RJ; Boobis AR; Pasanen M
    Biol Neonate; 2001; 80(3):193-201. PubMed ID: 11585982
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells.
    Rodríguez-Antona C; Donato MT; Boobis A; Edwards RJ; Watts PS; Castell JV; Gómez-Lechón MJ
    Xenobiotica; 2002 Jun; 32(6):505-20. PubMed ID: 12160483
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Follow-up to the pre-validation of a harmonised protocol for assessment of CYP induction responses in freshly isolated and cryopreserved human hepatocytes with respect to culture format, treatment, positive reference inducers and incubation conditions.
    Abadie-Viollon C; Martin H; Blanchard N; Pekthong D; Bachellier P; Mantion G; Heyd B; Schuler F; Coassolo P; Alexandre E; Richert L
    Toxicol In Vitro; 2010 Feb; 24(1):346-56. PubMed ID: 19497360
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Enzyme induction and cytotoxicity in human hepatocytes by chlorpyrifos and N,N-diethyl-m-toluamide (DEET).
    Das PC; Cao Y; Rose RL; Cherrington N; Hodgson E
    Drug Metabol Drug Interact; 2008; 23(3-4):237-60. PubMed ID: 19326769
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
    Sahi J; Shord SS; Lindley C; Ferguson S; LeCluyse EL
    J Biochem Mol Toxicol; 2009; 23(1):43-58. PubMed ID: 19202563
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
    Westerink WM; Schoonen WG
    Toxicol In Vitro; 2007 Dec; 21(8):1581-91. PubMed ID: 17637504
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Stable overexpression of pregnane X receptor in HepG2 cells increases its potential for bioartificial liver application.
    Nibourg GA; Huisman MT; van der Hoeven TV; van Gulik TM; Chamuleau RA; Hoekstra R
    Liver Transpl; 2010 Sep; 16(9):1075-85. PubMed ID: 20818746
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The effect of cyclophosphamide with and without dexamethasone on cytochrome P450 3A4 and 2B6 in human hepatocytes.
    Lindley C; Hamilton G; McCune JS; Faucette S; Shord SS; Hawke RL; Wang H; Gilbert D; Jolley S; Yan B; LeCluyse EL
    Drug Metab Dispos; 2002 Jul; 30(7):814-22. PubMed ID: 12065440
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
    Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
    Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
    [TBL] [Abstract][Full Text] [Related]  

  • 35. An 'all-inclusive' 96-well cytochrome P450 induction method: measuring enzyme activity, mRNA levels, protein levels, and cytotoxicity from one well using cryopreserved human hepatocytes.
    Halladay JS; Wong S; Khojasteh SC; Grepper S
    J Pharmacol Toxicol Methods; 2012; 66(3):270-5. PubMed ID: 22809809
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Effects of time culture and prototypical cytochrome P450 3A (CYP3A) inducers on CYP2B22, CYP2C, CYP3A and nuclear receptor (NR) mRNAs in long-term cryopreserved pig hepatocytes (CPHs).
    Giantin M; Zancanella V; Lopparelli RM; Granato A; Carletti M; Vilei MT; Muraca M; Baratto C; Dacasto M
    Drug Metab Pharmacokinet; 2012; 27(5):495-505. PubMed ID: 22447117
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products.
    Raucy JL
    Drug Metab Dispos; 2003 May; 31(5):533-9. PubMed ID: 12695340
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Relative receptor expression is a determinant in xenobiotic-mediated CYP3A induction in rat and human cells.
    Swales K; Plant N; Ayrton A; Hood S; Gibson G
    Xenobiotica; 2003 Jul; 33(7):703-16. PubMed ID: 12893520
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA.
    Koch I; Weil R; Wolbold R; Brockmöller J; Hustert E; Burk O; Nuessler A; Neuhaus P; Eichelbaum M; Zanger U; Wojnowski L
    Drug Metab Dispos; 2002 Oct; 30(10):1108-14. PubMed ID: 12228187
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Expression of CYP3A in the human liver--evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth.
    Lacroix D; Sonnier M; Moncion A; Cheron G; Cresteil T
    Eur J Biochem; 1997 Jul; 247(2):625-34. PubMed ID: 9266706
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.