278 related articles for article (PubMed ID: 17982510)
1. Comparative evaluation of hERG potassium channel blockade by antipsychotics.
Silvestre JS; Prous JR
Methods Find Exp Clin Pharmacol; 2007 Sep; 29(7):457-65. PubMed ID: 17982510
[TBL] [Abstract][Full Text] [Related]
2. A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs.
Kongsamut S; Kang J; Chen XL; Roehr J; Rampe D
Eur J Pharmacol; 2002 Aug; 450(1):37-41. PubMed ID: 12176106
[TBL] [Abstract][Full Text] [Related]
3. The antipsychotic agent sertindole is a high affinity antagonist of the human cardiac potassium channel HERG.
Rampe D; Murawsky MK; Grau J; Lewis EW
J Pharmacol Exp Ther; 1998 Aug; 286(2):788-93. PubMed ID: 9694935
[TBL] [Abstract][Full Text] [Related]
4. Effects of antipsychotic drugs on I(to), I (Na), I (sus), I (K1), and hERG: QT prolongation, structure activity relationship, and network analysis.
Crumb WJ; Ekins S; Sarazan RD; Wikel JH; Wrighton SA; Carlson C; Beasley CM
Pharm Res; 2006 Jun; 23(6):1133-43. PubMed ID: 16715368
[TBL] [Abstract][Full Text] [Related]
5. Iloperidone (Fanapt®), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration.
Vigneault P; Pilote S; Patoine D; Simard C; Drolet B
Pharmacol Res; 2012 Jul; 66(1):60-5. PubMed ID: 22465688
[TBL] [Abstract][Full Text] [Related]
6. Development of a high-throughput electrophysiological assay for the human ether-à-go-go related potassium channel hERG.
Gillie DJ; Novick SJ; Donovan BT; Payne LA; Townsend C
J Pharmacol Toxicol Methods; 2013; 67(1):33-44. PubMed ID: 23103595
[TBL] [Abstract][Full Text] [Related]
7. Cyclovirobuxine D inhibits the currents of HERG potassium channels stably expressed in HEK293 cells.
Zhao J; Wang Q; Xu J; Zhao J; Liu G; Peng S
Eur J Pharmacol; 2011 Jun; 660(2-3):259-67. PubMed ID: 21497594
[TBL] [Abstract][Full Text] [Related]
8. The [3H]dofetilide binding assay is a predictive screening tool for hERG blockade and proarrhythmia: Comparison of intact cell and membrane preparations and effects of altering [K+]o.
Diaz GJ; Daniell K; Leitza ST; Martin RL; Su Z; McDermott JS; Cox BF; Gintant GA
J Pharmacol Toxicol Methods; 2004; 50(3):187-99. PubMed ID: 15519905
[TBL] [Abstract][Full Text] [Related]
9. Evidence for a crucial modulating role of the sodium channel in the QTc prolongation related to antipsychotics.
Silvestre JS; O'Neill MF; Prous JR
J Psychopharmacol; 2014 Apr; 28(4):329-40. PubMed ID: 24327451
[TBL] [Abstract][Full Text] [Related]
10. SKF-96365 blocks human ether-à-go-go-related gene potassium channels stably expressed in HEK 293 cells.
Liu H; Yang L; Chen KH; Sun HY; Jin MW; Xiao GS; Wang Y; Li GR
Pharmacol Res; 2016 Feb; 104():61-9. PubMed ID: 26689773
[TBL] [Abstract][Full Text] [Related]
11. High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872.
Thomas D; Wendt-Nordahl G; Röckl K; Ficker E; Brown AM; Kiehn J
J Pharmacol Exp Ther; 2001 May; 297(2):753-61. PubMed ID: 11303067
[TBL] [Abstract][Full Text] [Related]
12. Blockade of HERG cardiac K+ current by antifungal drug miconazole.
Kikuchi K; Nagatomo T; Abe H; Kawakami K; Duff HJ; Makielski JC; January CT; Nakashima Y
Br J Pharmacol; 2005 Mar; 144(6):840-8. PubMed ID: 15778703
[TBL] [Abstract][Full Text] [Related]
13. Allosteric modulators of the hERG K(+) channel: radioligand binding assays reveal allosteric characteristics of dofetilide analogs.
Yu Z; Klaasse E; Heitman LH; Ijzerman AP
Toxicol Appl Pharmacol; 2014 Jan; 274(1):78-86. PubMed ID: 24200993
[TBL] [Abstract][Full Text] [Related]
14. Fluconazole inhibits hERG K(+) channel by direct block and disruption of protein trafficking.
Han S; Zhang Y; Chen Q; Duan Y; Zheng T; Hu X; Zhang Z; Zhang L
Eur J Pharmacol; 2011 Jan; 650(1):138-44. PubMed ID: 20951697
[TBL] [Abstract][Full Text] [Related]
15. Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine.
Lee SY; Kim YJ; Kim KT; Choe H; Jo SH
Br J Pharmacol; 2006 Jun; 148(4):499-509. PubMed ID: 16633353
[TBL] [Abstract][Full Text] [Related]
16. The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes.
Suessbrich H; Schönherr R; Heinemann SH; Attali B; Lang F; Busch AE
Br J Pharmacol; 1997 Mar; 120(5):968-74. PubMed ID: 9138706
[TBL] [Abstract][Full Text] [Related]
17. The action of a novel fluoroquinolone antibiotic agent antofloxacin hydrochloride on human-ether-à-go-go-related gene potassium channel.
Guo J; Han SN; Liu JX; Zhang XM; Hu ZS; Shi J; Zhang LR; Zhao ZZ; Zhang Z
Basic Clin Pharmacol Toxicol; 2010 Aug; 107(2):643-9. PubMed ID: 20662825
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of the HERG channel by droperidol depends on channel gating and involves the S6 residue F656.
Luo T; Luo A; Liu M; Liu X
Anesth Analg; 2008 Apr; 106(4):1161-70, table of contents. PubMed ID: 18349188
[TBL] [Abstract][Full Text] [Related]
19. Propofol inhibits hERG K
Han SN; Jing Y; Yang LL; Zhang Z; Zhang LR
Eur J Pharmacol; 2016 Nov; 791():168-178. PubMed ID: 27575519
[TBL] [Abstract][Full Text] [Related]
20. Evaluation of functional and binding assays in cells expressing either recombinant or endogenous hERG channel.
Murphy SM; Palmer M; Poole MF; Padegimas L; Hunady K; Danzig J; Gill S; Gill R; Ting A; Sherf B; Brunden K; Stricker-Krongrad A
J Pharmacol Toxicol Methods; 2006; 54(1):42-55. PubMed ID: 16326118
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
