BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 17984046)

  • 1. Loss of luminal Ca2+ activation in the cardiac ryanodine receptor is associated with ventricular fibrillation and sudden death.
    Jiang D; Chen W; Wang R; Zhang L; Chen SR
    Proc Natl Acad Sci U S A; 2007 Nov; 104(46):18309-14. PubMed ID: 17984046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enhanced store overload-induced Ca2+ release and channel sensitivity to luminal Ca2+ activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden death.
    Jiang D; Wang R; Xiao B; Kong H; Hunt DJ; Choi P; Zhang L; Chen SR
    Circ Res; 2005 Nov; 97(11):1173-81. PubMed ID: 16239587
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of loss-of-function RyR2 mutations associated with idiopathic ventricular fibrillation and sudden death.
    Zhong X; Guo W; Wei J; Tang Y; Liu Y; Zhang JZ; Tan VH; Zhang L; Wang R; Jones PP; Napolitano C; Priori SG; Chen SRW
    Biosci Rep; 2021 Apr; 41(4):. PubMed ID: 33825858
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Endoplasmic reticulum Ca2+ measurements reveal that the cardiac ryanodine receptor mutations linked to cardiac arrhythmia and sudden death alter the threshold for store-overload-induced Ca2+ release.
    Jones PP; Jiang D; Bolstad J; Hunt DJ; Zhang L; Demaurex N; Chen SR
    Biochem J; 2008 May; 412(1):171-8. PubMed ID: 18092949
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR).
    Jiang D; Xiao B; Yang D; Wang R; Choi P; Zhang L; Cheng H; Chen SR
    Proc Natl Acad Sci U S A; 2004 Aug; 101(35):13062-7. PubMed ID: 15322274
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.
    Kong H; Wang R; Chen W; Zhang L; Chen K; Shimoni Y; Duff HJ; Chen SR
    Biophys J; 2007 Apr; 92(8):2757-70. PubMed ID: 17259277
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Arrhythmogenesis in a catecholaminergic polymorphic ventricular tachycardia mutation that depresses ryanodine receptor function.
    Zhao YT; Valdivia CR; Gurrola GB; Powers PP; Willis BC; Moss RL; Jalife J; Valdivia HH
    Proc Natl Acad Sci U S A; 2015 Mar; 112(13):E1669-77. PubMed ID: 25775566
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional consequence of protein kinase A-dependent phosphorylation of the cardiac ryanodine receptor: sensitization of store overload-induced Ca2+ release.
    Xiao B; Tian X; Xie W; Jones PP; Cai S; Wang X; Jiang D; Kong H; Zhang L; Chen K; Walsh MP; Cheng H; Chen SR
    J Biol Chem; 2007 Oct; 282(41):30256-64. PubMed ID: 17693412
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The CPVT-associated RyR2 mutation G230C enhances store overload-induced Ca2+ release and destabilizes the N-terminal domains.
    Liu Y; Kimlicka L; Hiess F; Tian X; Wang R; Zhang L; Jones PP; Van Petegem F; Chen SR
    Biochem J; 2013 Aug; 454(1):123-31. PubMed ID: 23746327
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reduced threshold for store overload-induced Ca
    Chen W; Koop A; Liu Y; Guo W; Wei J; Wang R; MacLennan DH; Dirksen RT; Chen SRW
    Biochem J; 2017 Aug; 474(16):2749-2761. PubMed ID: 28687594
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of a novel mutation in the cardiac ryanodine receptor that results in catecholaminergic polymorphic ventricular tachycardia.
    Jiang D; Jones PP; Davis DR; Gow R; Green MS; Birnie DH; Chen SR; Gollob MH
    Channels (Austin); 2010; 4(4):302-10. PubMed ID: 20676041
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The EF-hand Ca2+ Binding Domain Is Not Required for Cytosolic Ca2+ Activation of the Cardiac Ryanodine Receptor.
    Guo W; Sun B; Xiao Z; Liu Y; Wang Y; Zhang L; Wang R; Chen SR
    J Biol Chem; 2016 Jan; 291(5):2150-60. PubMed ID: 26663082
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A gain of function ryanodine receptor 2 mutation (R1760W-RyR2) in catecholaminergic polymorphic ventricular tachycardia.
    Li S; Lv T; Yang J; Li K; Yang Y; Zhang P
    Clin Exp Pharmacol Physiol; 2023 Jan; 50(1):39-49. PubMed ID: 36082968
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias.
    Chen W; Wang R; Chen B; Zhong X; Kong H; Bai Y; Zhou Q; Xie C; Zhang J; Guo A; Tian X; Jones PP; O'Mara ML; Liu Y; Mi T; Zhang L; Bolstad J; Semeniuk L; Cheng H; Zhang J; Chen J; Tieleman DP; Gillis AM; Duff HJ; Fill M; Song LS; Chen SR
    Nat Med; 2014 Feb; 20(2):184-92. PubMed ID: 24441828
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Arrhythmogenic Calmodulin Mutations Affect the Activation and Termination of Cardiac Ryanodine Receptor-mediated Ca2+ Release.
    Søndergaard MT; Tian X; Liu Y; Wang R; Chazin WJ; Chen SR; Overgaard MT
    J Biol Chem; 2015 Oct; 290(43):26151-62. PubMed ID: 26309258
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enhanced basal activity of a cardiac Ca2+ release channel (ryanodine receptor) mutant associated with ventricular tachycardia and sudden death.
    Jiang D; Xiao B; Zhang L; Chen SR
    Circ Res; 2002 Aug; 91(3):218-25. PubMed ID: 12169647
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhanced Cytosolic Ca2+ Activation Underlies a Common Defect of Central Domain Cardiac Ryanodine Receptor Mutations Linked to Arrhythmias.
    Xiao Z; Guo W; Sun B; Hunt DJ; Wei J; Liu Y; Wang Y; Wang R; Jones PP; Back TG; Chen SRW
    J Biol Chem; 2016 Nov; 291(47):24528-24537. PubMed ID: 27733687
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nebivolol suppresses cardiac ryanodine receptor-mediated spontaneous Ca2+ release and catecholaminergic polymorphic ventricular tachycardia.
    Tan Z; Xiao Z; Wei J; Zhang J; Zhou Q; Smith CD; Nani A; Wu G; Song LS; Back TG; Fill M; Chen SR
    Biochem J; 2016 Nov; 473(22):4159-4172. PubMed ID: 27623776
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Caffeine induces Ca2+ release by reducing the threshold for luminal Ca2+ activation of the ryanodine receptor.
    Kong H; Jones PP; Koop A; Zhang L; Duff HJ; Chen SR
    Biochem J; 2008 Sep; 414(3):441-52. PubMed ID: 18518861
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel ryanodine receptor mutation linked to sudden death increases sensitivity to cytosolic calcium.
    Meli AC; Refaat MM; Dura M; Reiken S; Wronska A; Wojciak J; Carroll J; Scheinman MM; Marks AR
    Circ Res; 2011 Jul; 109(3):281-90. PubMed ID: 21659649
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.