219 related articles for article (PubMed ID: 17985858)
1. Design and synthesis of novel and potent inhibitors of the type II transmembrane serine protease, matriptase, based upon the sunflower trypsin inhibitor-1.
Li P; Jiang S; Lee SL; Lin CY; Johnson MD; Dickson RB; Michejda CJ; Roller PP
J Med Chem; 2007 Nov; 50(24):5976-83. PubMed ID: 17985858
[TBL] [Abstract][Full Text] [Related]
2. Design and synthesis of redox stable analogues of sunflower trypsin inhibitors (SFTI-1) on solid support, potent inhibitors of matriptase.
Jiang S; Li P; Lee SL; Lin CY; Long YQ; Johnson MD; Dickson RB; Roller PP
Org Lett; 2007 Jan; 9(1):9-12. PubMed ID: 17192072
[TBL] [Abstract][Full Text] [Related]
3. High-affinity cyclic peptide matriptase inhibitors.
Quimbar P; Malik U; Sommerhoff CP; Kaas Q; Chan LY; Huang YH; Grundhuber M; Dunse K; Craik DJ; Anderson MA; Daly NL
J Biol Chem; 2013 May; 288(19):13885-96. PubMed ID: 23548907
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and evaluation of the sunflower derived trypsin inhibitor as a potent inhibitor of the type II transmembrane serine protease, matriptase.
Long YQ; Lee SL; Lin CY; Enyedy IJ; Wang S; Li P; Dickson RB; Roller PP
Bioorg Med Chem Lett; 2001 Sep; 11(18):2515-9. PubMed ID: 11549459
[TBL] [Abstract][Full Text] [Related]
5. Design and chemical syntheses of potent matriptase-2 inhibitors based on trypsin inhibitor SFTI-1 isolated from sunflower seeds.
Gitlin-Domagalska A; Dębowski D; Łęgowska A; Stirnberg M; Okońska J; Gütschow M; Rolka K
Biopolymers; 2017 Nov; 108(6):. PubMed ID: 28555756
[TBL] [Abstract][Full Text] [Related]
6. Potent inhibitors of human matriptase-1 based on the scaffold of sunflower trypsin inhibitor.
Fittler H; Avrutina O; Empting M; Kolmar H
J Pept Sci; 2014 Jun; 20(6):415-20. PubMed ID: 24723440
[TBL] [Abstract][Full Text] [Related]
7. Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1.
Yuan C; Chen L; Meehan EJ; Daly N; Craik DJ; Huang M; Ngo JC
BMC Struct Biol; 2011 Jun; 11():30. PubMed ID: 21693064
[TBL] [Abstract][Full Text] [Related]
8. Inhibitors of Matriptase-2 Based on the Trypsin Inhibitor SFTI-1.
Gitlin A; Dębowski D; Karna N; Łęgowska A; Stirnberg M; Gütschow M; Rolka K
Chembiochem; 2015 Jul; 16(11):1601-7. PubMed ID: 25999208
[TBL] [Abstract][Full Text] [Related]
9. Structure-based approach for the discovery of bis-benzamidines as novel inhibitors of matriptase.
Enyedy IJ; Lee SL; Kuo AH; Dickson RB; Lin CY; Wang S
J Med Chem; 2001 Apr; 44(9):1349-55. PubMed ID: 11311057
[TBL] [Abstract][Full Text] [Related]
10. Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets.
Franco FM; Jones DE; Harris PK; Han Z; Wildman SA; Jarvis CM; Janetka JW
Bioorg Med Chem; 2015 May; 23(10):2328-43. PubMed ID: 25882520
[TBL] [Abstract][Full Text] [Related]
11. Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy.
Goswami R; Mukherjee S; Ghadiyaram C; Wohlfahrt G; Sistla RK; Nagaraj J; Satyam LK; Subbarao K; Palakurthy RK; Gopinath S; Krishnamurthy NR; Ikonen T; Moilanen A; Subramanya HS; Kallio P; Ramachandra M
Bioorg Med Chem; 2014 Jun; 22(12):3187-203. PubMed ID: 24794746
[TBL] [Abstract][Full Text] [Related]
12. Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1.
de Veer SJ; Li CY; Swedberg JE; Schroeder CI; Craik DJ
Eur J Med Chem; 2018 Jul; 155():695-704. PubMed ID: 29936356
[TBL] [Abstract][Full Text] [Related]
13. Combinatorial tuning of peptidic drug candidates: high-affinity matriptase inhibitors through incremental structure-guided optimization.
Fittler H; Avrutina O; Glotzbach B; Empting M; Kolmar H
Org Biomol Chem; 2013 Mar; 11(11):1848-57. PubMed ID: 23361403
[TBL] [Abstract][Full Text] [Related]
14. Introduction of alpha-hydroxymethyamino acid residues in substrate specificity P1 position of trypsin inhibitor SFTI-1 from sunflower seeds retains its activity.
Zabłotna E; Kret A; Jaśkiewicz A; Olma A; Leplawy MT; Rolka K
Biochem Biophys Res Commun; 2006 Feb; 340(3):823-8. PubMed ID: 16380077
[TBL] [Abstract][Full Text] [Related]
15. Discovery of O-(3-carbamimidoylphenyl)-l-serine amides as matriptase inhibitors using a fragment-linking approach.
Goswami R; Wohlfahrt G; Mukherjee S; Ghadiyaram C; Nagaraj J; Satyam LK; Subbarao K; Gopinath S; Krishnamurthy NR; Subramanya HS; Ramachandra M
Bioorg Med Chem Lett; 2015 Feb; 25(3):616-20. PubMed ID: 25556099
[TBL] [Abstract][Full Text] [Related]
16. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.
Katz BA; Elrod K; Luong C; Rice MJ; Mackman RL; Sprengeler PA; Spencer J; Hataye J; Janc J; Link J; Litvak J; Rai R; Rice K; Sideris S; Verner E; Young W
J Mol Biol; 2001 Apr; 307(5):1451-86. PubMed ID: 11292354
[TBL] [Abstract][Full Text] [Related]
17. Between two worlds: a comparative study on in vitro and in silico inhibition of trypsin and matriptase by redox-stable SFTI-1 variants at near physiological pH.
Avrutina O; Fittler H; Glotzbach B; Kolmar H; Empting M
Org Biomol Chem; 2012 Oct; 10(38):7753-62. PubMed ID: 22903577
[TBL] [Abstract][Full Text] [Related]
18. Immobilized analogues of sunflower trypsin inhibitor-1 constitute a versatile group of affinity sorbents for selective isolation of serine proteases.
Pereira HJ; Salgado MC; Oliveira EB
J Chromatogr B Analyt Technol Biomed Life Sci; 2009 Jul; 877(22):2039-44. PubMed ID: 19515617
[TBL] [Abstract][Full Text] [Related]
19. Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library.
de Veer SJ; Wang CK; Harris JM; Craik DJ; Swedberg JE
J Med Chem; 2015 Oct; 58(20):8257-68. PubMed ID: 26393374
[TBL] [Abstract][Full Text] [Related]
20. [Prospects for the design of new therapeutically significant protease inhibitors based on knottins and sunflower seed trypsin inhibitor (SFTI 1)].
Kuznetsova SS; Kolesanova EF; Talanova AV; Veselovsky AV
Biomed Khim; 2016 May; 62(4):353-68. PubMed ID: 27562989
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
