480 related articles for article (PubMed ID: 17989065)
1. ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones.
Wei H; Kim SJ; Zhang Z; Tsai PC; Wisniewski KE; Mukherjee AB
Hum Mol Genet; 2008 Feb; 17(4):469-77. PubMed ID: 17989065
[TBL] [Abstract][Full Text] [Related]
2. Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders.
Chandra G; Bagh MB; Peng S; Saha A; Sarkar C; Moralle M; Zhang Z; Mukherjee AB
Hum Mol Genet; 2015 Oct; 24(19):5416-32. PubMed ID: 26160911
[TBL] [Abstract][Full Text] [Related]
3. Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL.
Kim SJ; Zhang Z; Lee YC; Mukherjee AB
Hum Mol Genet; 2006 May; 15(10):1580-6. PubMed ID: 16571600
[TBL] [Abstract][Full Text] [Related]
4. Cln3-mutations underlying juvenile neuronal ceroid lipofuscinosis cause significantly reduced levels of Palmitoyl-protein thioesterases-1 (Ppt1)-protein and Ppt1-enzyme activity in the lysosome.
Appu AP; Bagh MB; Sadhukhan T; Mondal A; Casey S; Mukherjee AB
J Inherit Metab Dis; 2019 Sep; 42(5):944-954. PubMed ID: 31025705
[TBL] [Abstract][Full Text] [Related]
5. Human INCL fibroblasts display abnormal mitochondrial and lysosomal networks and heightened susceptibility to ROS-induced cell death.
Balouch B; Nagorsky H; Pham T; LaGraff JT; Chu-LaGraff Q
PLoS One; 2021; 16(2):e0239689. PubMed ID: 33561134
[TBL] [Abstract][Full Text] [Related]
6. Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL.
Zhang Z; Lee YC; Kim SJ; Choi MS; Tsai PC; Xu Y; Xiao YJ; Zhang P; Heffer A; Mukherjee AB
Hum Mol Genet; 2006 Jan; 15(2):337-46. PubMed ID: 16368712
[TBL] [Abstract][Full Text] [Related]
7. Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL.
Kim SJ; Zhang Z; Hitomi E; Lee YC; Mukherjee AB
Hum Mol Genet; 2006 Jun; 15(11):1826-34. PubMed ID: 16644870
[TBL] [Abstract][Full Text] [Related]
8. Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol.
Wei H; Zhang Z; Saha A; Peng S; Chandra G; Quezado Z; Mukherjee AB
Hum Mol Genet; 2011 Mar; 20(6):1111-21. PubMed ID: 21224254
[TBL] [Abstract][Full Text] [Related]
9. Omega-3 and omega-6 fatty acids suppress ER- and oxidative stress in cultured neurons and neuronal progenitor cells from mice lacking PPT1.
Kim SJ; Zhang Z; Saha A; Sarkar C; Zhao Z; Xu Y; Mukherjee AB
Neurosci Lett; 2010 Aug; 479(3):292-6. PubMed ID: 20561933
[TBL] [Abstract][Full Text] [Related]
10. Neuroprotection and lifespan extension in Ppt1(-/-) mice by NtBuHA: therapeutic implications for INCL.
Sarkar C; Chandra G; Peng S; Zhang Z; Liu A; Mukherjee AB
Nat Neurosci; 2013 Nov; 16(11):1608-17. PubMed ID: 24056696
[TBL] [Abstract][Full Text] [Related]
11. Cln1-mutations suppress Rab7-RILP interaction and impair autophagy contributing to neuropathology in a mouse model of infantile neuronal ceroid lipofuscinosis.
Sarkar C; Sadhukhan T; Bagh MB; Appu AP; Chandra G; Mondal A; Saha A; Mukherjee AB
J Inherit Metab Dis; 2020 Sep; 43(5):1082-1101. PubMed ID: 32279353
[TBL] [Abstract][Full Text] [Related]
12. Ppt1-deficiency dysregulates lysosomal Ca
Mondal A; Appu AP; Sadhukhan T; Bagh MB; Previde RM; Sadhukhan S; Stojilkovic S; Liu A; Mukherjee AB
J Inherit Metab Dis; 2022 May; 45(3):635-656. PubMed ID: 35150145
[TBL] [Abstract][Full Text] [Related]
13. Protective potential of resveratrol against oxidative stress and apoptosis in Batten disease lymphoblast cells.
Yoon DH; Kwon OY; Mang JY; Jung MJ; Kim DY; Park YK; Heo TH; Kim SJ
Biochem Biophys Res Commun; 2011 Oct; 414(1):49-52. PubMed ID: 21945436
[TBL] [Abstract][Full Text] [Related]
14. Lysosomal ceroid depletion by drugs: therapeutic implications for a hereditary neurodegenerative disease of childhood.
Zhang Z; Butler JD; Levin SW; Wisniewski KE; Brooks SS; Mukherjee AB
Nat Med; 2001 Apr; 7(4):478-84. PubMed ID: 11283676
[TBL] [Abstract][Full Text] [Related]
15. Stop codon read-through with PTC124 induces palmitoyl-protein thioesterase-1 activity, reduces thioester load and suppresses apoptosis in cultured cells from INCL patients.
Sarkar C; Zhang Z; Mukherjee AB
Mol Genet Metab; 2011 Nov; 104(3):338-45. PubMed ID: 21704547
[TBL] [Abstract][Full Text] [Related]
16. Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 and ERp57.
Corazzari M; Lovat PE; Armstrong JL; Fimia GM; Hill DS; Birch-Machin M; Redfern CP; Piacentini M
Br J Cancer; 2007 Apr; 96(7):1062-71. PubMed ID: 17353921
[TBL] [Abstract][Full Text] [Related]
17. Mitochondrial Dysfunction and Neurodegeneration in Lysosomal Storage Disorders.
Plotegher N; Duchen MR
Trends Mol Med; 2017 Feb; 23(2):116-134. PubMed ID: 28111024
[TBL] [Abstract][Full Text] [Related]
18. CLN3 is required for the clearance of glycerophosphodiesters from lysosomes.
Laqtom NN; Dong W; Medoh UN; Cangelosi AL; Dharamdasani V; Chan SH; Kunchok T; Lewis CA; Heinze I; Tang R; Grimm C; Dang Do AN; Porter FD; Ori A; Sabatini DM; Abu-Remaileh M
Nature; 2022 Sep; 609(7929):1005-1011. PubMed ID: 36131016
[TBL] [Abstract][Full Text] [Related]
19. Lysosomal storage diseases--the horizon expands.
Boustany RM
Nat Rev Neurol; 2013 Oct; 9(10):583-98. PubMed ID: 23938739
[TBL] [Abstract][Full Text] [Related]
20. Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration.
Kasper D; Planells-Cases R; Fuhrmann JC; Scheel O; Zeitz O; Ruether K; Schmitt A; Poët M; Steinfeld R; Schweizer M; Kornak U; Jentsch TJ
EMBO J; 2005 Mar; 24(5):1079-91. PubMed ID: 15706348
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]