165 related articles for article (PubMed ID: 17990984)
1. Enzyme substrate recognition in oxygen sensing: how the HIF trap snaps.
Metzen E
Biochem J; 2007 Dec; 408(2):e5-6. PubMed ID: 17990984
[TBL] [Abstract][Full Text] [Related]
2. Identification of a region on hypoxia-inducible-factor prolyl 4-hydroxylases that determines their specificity for the oxygen degradation domains.
Villar D; Vara-Vega A; Landázuri MO; Del Peso L
Biochem J; 2007 Dec; 408(2):231-40. PubMed ID: 17725546
[TBL] [Abstract][Full Text] [Related]
3. Structural basis for binding of the renal carcinoma target hypoxia-inducible factor 2α to prolyl hydroxylase domain 2.
Figg WD; Fiorini G; Chowdhury R; Nakashima Y; Tumber A; McDonough MA; Schofield CJ
Proteins; 2023 Nov; 91(11):1510-1524. PubMed ID: 37449559
[TBL] [Abstract][Full Text] [Related]
4. Analysis of HIF-prolyl hydroxylases binding to substrates.
Landázuri MO; Vara-Vega A; Vitón M; Cuevas Y; del Peso L
Biochem Biophys Res Commun; 2006 Dec; 351(2):313-20. PubMed ID: 17069766
[TBL] [Abstract][Full Text] [Related]
5. A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery.
Alcaide-German ML; Vara-Vega A; Garcia-Fernandez LF; Landazuri MO; del Peso L
BMC Cell Biol; 2008 Apr; 9():18. PubMed ID: 18402654
[TBL] [Abstract][Full Text] [Related]
6. Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Chowdhury R; Leung IK; Tian YM; Abboud MI; Ge W; Domene C; Cantrelle FX; Landrieu I; Hardy AP; Pugh CW; Ratcliffe PJ; Claridge TD; Schofield CJ
Nat Commun; 2016 Aug; 7():12673. PubMed ID: 27561929
[TBL] [Abstract][Full Text] [Related]
7. Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.
Metzen E; Berchner-Pfannschmidt U; Stengel P; Marxsen JH; Stolze I; Klinger M; Huang WQ; Wotzlaw C; Hellwig-Bürgel T; Jelkmann W; Acker H; Fandrey J
J Cell Sci; 2003 Apr; 116(Pt 7):1319-26. PubMed ID: 12615973
[TBL] [Abstract][Full Text] [Related]
8. Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from
Liu T; Abboud MI; Chowdhury R; Tumber A; Hardy AP; Lippl K; Lohans CT; Pires E; Wickens J; McDonough MA; West CM; Schofield CJ
J Biol Chem; 2020 Dec; 295(49):16545-16561. PubMed ID: 32934009
[TBL] [Abstract][Full Text] [Related]
9. Biochemical characterization of human HIF hydroxylases using HIF protein substrates that contain all three hydroxylation sites.
Pappalardi MB; McNulty DE; Martin JD; Fisher KE; Jiang Y; Burns MC; Zhao H; Ho T; Sweitzer S; Schwartz B; Annan RS; Copeland RA; Tummino PJ; Luo L
Biochem J; 2011 Jun; 436(2):363-9. PubMed ID: 21410436
[TBL] [Abstract][Full Text] [Related]
10. Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change.
Pektas S; Knapp MJ
J Inorg Biochem; 2013 Sep; 126():55-60. PubMed ID: 23787140
[TBL] [Abstract][Full Text] [Related]
11. Studies on the Substrate Selectivity of the Hypoxia-Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain.
Abboud MI; Chowdhury R; Leung IKH; Lippl K; Loenarz C; Claridge TDW; Schofield CJ
Chembiochem; 2018 Nov; 19(21):2262-2267. PubMed ID: 30144273
[TBL] [Abstract][Full Text] [Related]
12. The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen.
del Peso L; Castellanos MC; Temes E; Martin-Puig S; Cuevas Y; Olmos G; Landazuri MO
J Biol Chem; 2003 Dec; 278(49):48690-5. PubMed ID: 14506252
[TBL] [Abstract][Full Text] [Related]
13. HIF hydroxylation and cellular oxygen sensing.
Metzen E; Ratcliffe PJ
Biol Chem; 2004; 385(3-4):223-30. PubMed ID: 15134335
[TBL] [Abstract][Full Text] [Related]
14. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
15. Kinetic rationale for selectivity toward N- and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases.
Flashman E; Bagg EA; Chowdhury R; Mecinović J; Loenarz C; McDonough MA; Hewitson KS; Schofield CJ
J Biol Chem; 2008 Feb; 283(7):3808-15. PubMed ID: 18063574
[TBL] [Abstract][Full Text] [Related]
16. Hypoxia-dependent sequestration of an oxygen sensor by a widespread structural motif can shape the hypoxic response--a predictive kinetic model.
Schmierer B; Novák B; Schofield CJ
BMC Syst Biol; 2010 Oct; 4():139. PubMed ID: 20955552
[TBL] [Abstract][Full Text] [Related]
17. The non-canonical functions of HIF prolyl hydroxylases and their dual roles in cancer.
Yu M; Lun J; Zhang H; Zhu L; Zhang G; Fang J
Int J Biochem Cell Biol; 2021 Jun; 135():105982. PubMed ID: 33894356
[TBL] [Abstract][Full Text] [Related]
18. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
Appelhoff RJ; Tian YM; Raval RR; Turley H; Harris AL; Pugh CW; Ratcliffe PJ; Gleadle JM
J Biol Chem; 2004 Sep; 279(37):38458-65. PubMed ID: 15247232
[TBL] [Abstract][Full Text] [Related]
19. Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.
Hewitson KS; Schofield CJ; Ratcliffe PJ
Methods Enzymol; 2007; 435():25-42. PubMed ID: 17998047
[TBL] [Abstract][Full Text] [Related]
20. PHD1 interacts with ATF4 and negatively regulates its transcriptional activity without prolyl hydroxylation.
Hiwatashi Y; Kanno K; Takasaki C; Goryo K; Sato T; Torii S; Sogawa K; Yasumoto K
Exp Cell Res; 2011 Dec; 317(20):2789-99. PubMed ID: 21951999
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
