BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 17991758)

  • 1. Cyclical and alternating infusions of glucose and intralipid in rats inhibit insulin gene expression and Pdx-1 binding in islets.
    Hagman DK; Latour MG; Chakrabarti SK; Fontes G; Amyot J; Tremblay C; Semache M; Lausier JA; Roskens V; Mirmira RG; Jetton TL; Poitout V
    Diabetes; 2008 Feb; 57(2):424-31. PubMed ID: 17991758
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation.
    Sako Y; Grill VE
    Endocrinology; 1990 Oct; 127(4):1580-9. PubMed ID: 1698143
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prolonged elevation of plasma free fatty acids desensitizes the insulin secretory response to glucose in vivo in rats.
    Mason TM; Goh T; Tchipashvili V; Sandhu H; Gupta N; Lewis GF; Giacca A
    Diabetes; 1999 Mar; 48(3):524-30. PubMed ID: 10078552
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Palmitic acid increase levels of pancreatic duodenal homeobox-1 and p38/stress-activated protein kinase in islets from rats maintained on a low protein diet.
    Arantes VC; Reis MA; Latorraca MQ; Ferreira F; Stoppiglia LF; Carneiro EM; Boschero AC
    Br J Nutr; 2006 Dec; 96(6):1006-12. PubMed ID: 17181874
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects.
    Paolisso G; Gambardella A; Amato L; Tortoriello R; D'Amore A; Varricchio M; D'Onofrio F
    Diabetologia; 1995 Nov; 38(11):1295-9. PubMed ID: 8582538
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lipopolysaccharides impair insulin gene expression in isolated islets of Langerhans via Toll-Like Receptor-4 and NF-κB signalling.
    Amyot J; Semache M; Ferdaoussi M; Fontés G; Poitout V
    PLoS One; 2012; 7(4):e36200. PubMed ID: 22558381
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Elevation of plasma fatty acids by ten-hour intralipid infusion has no effect on basal or glucose-stimulated insulin secretion in normal man.
    Amery CM; Round RA; Smith JM; Nattrass M
    Metabolism; 2000 Apr; 49(4):450-4. PubMed ID: 10778867
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans.
    Hagman DK; Hays LB; Parazzoli SD; Poitout V
    J Biol Chem; 2005 Sep; 280(37):32413-8. PubMed ID: 15944145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Elevated circulating free fatty acids levels causing pancreatic islet cell dysfunction through oxidative stress.
    Zhang X; Bao Y; Ke L; Yu Y
    J Endocrinol Invest; 2010 Jun; 33(6):388-94. PubMed ID: 19915385
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo prevention of hyperglycemia also prevents glucotoxic effects on PDX-1 and insulin gene expression.
    Harmon JS; Gleason CE; Tanaka Y; Oseid EA; Hunter-Berger KK; Robertson RP
    Diabetes; 1999 Oct; 48(10):1995-2000. PubMed ID: 10512364
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats.
    Perfetti R; Zhou J; Doyle ME; Egan JM
    Endocrinology; 2000 Dec; 141(12):4600-5. PubMed ID: 11108273
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential effects of hyperlipidemia on insulin secretion in islets of langerhans from hyperglycemic versus normoglycemic rats.
    Briaud I; Kelpe CL; Johnson LM; Tran PO; Poitout V
    Diabetes; 2002 Mar; 51(3):662-8. PubMed ID: 11872664
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prolonged increase of plasma non-esterified fatty acids fully abolishes the stimulatory effect of 24 hours of moderate hyperglycaemia on insulin sensitivity and pancreatic beta-cell function in obese men.
    Leung N; Sakaue T; Carpentier A; Uffelman K; Giacca A; Lewis GF
    Diabetologia; 2004 Feb; 47(2):204-13. PubMed ID: 14712348
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression.
    Steil GM; Trivedi N; Jonas JC; Hasenkamp WM; Sharma A; Bonner-Weir S; Weir GC
    Am J Physiol Endocrinol Metab; 2001 May; 280(5):E788-96. PubMed ID: 11287362
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective induction of inducible nitric oxide synthase in pancreatic islet of rat after an intravenous glucose or intralipid challenge.
    Ekelund M; Qader SS; Jimenez-Feltstrom J; Salehi A
    Nutrition; 2006 Jun; 22(6):652-60. PubMed ID: 16635563
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pancreatic and duodenal homeobox-1 nuclear localization is regulated by glucose in dispersed rat islets but not in insulin-secreting cell lines.
    Semache M; Ghislain J; Zarrouki B; Tremblay C; Poitout V
    Islets; 2014; 6(4):e982376. PubMed ID: 25437380
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes.
    Kashyap S; Belfort R; Gastaldelli A; Pratipanawatr T; Berria R; Pratipanawatr W; Bajaj M; Mandarino L; DeFronzo R; Cusi K
    Diabetes; 2003 Oct; 52(10):2461-74. PubMed ID: 14514628
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo.
    Oprescu AI; Bikopoulos G; Naassan A; Allister EM; Tang C; Park E; Uchino H; Lewis GF; Fantus IG; Rozakis-Adcock M; Wheeler MB; Giacca A
    Diabetes; 2007 Dec; 56(12):2927-37. PubMed ID: 17717282
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene.
    Stefan N; Fritsche A; Häring H; Stumvoll M
    Diabetes; 2001 May; 50(5):1143-8. PubMed ID: 11334419
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of free fatty acids on beta-cell functions: a possible involvement of peroxisome proliferator-activated receptors alpha or pancreatic/duodenal homeobox.
    Yoshikawa H; Tajiri Y; Sako Y; Hashimoto T; Umeda F; Nawata H
    Metabolism; 2001 May; 50(5):613-8. PubMed ID: 11319727
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.