BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1090 related articles for article (PubMed ID: 17991856)

  • 1. IRE1 signaling affects cell fate during the unfolded protein response.
    Lin JH; Li H; Yasumura D; Cohen HR; Zhang C; Panning B; Shokat KM; Lavail MM; Walter P
    Science; 2007 Nov; 318(5852):944-9. PubMed ID: 17991856
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective activation of ATF6 and PERK endoplasmic reticulum stress signaling pathways prevent mutant rhodopsin accumulation.
    Chiang WC; Hiramatsu N; Messah C; Kroeger H; Lin JH
    Invest Ophthalmol Vis Sci; 2012 Oct; 53(11):7159-66. PubMed ID: 22956602
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effects of IRE1, ATF6, and PERK signaling on adRP-linked rhodopsins.
    Jerry Chiang WC; Lin JH
    Adv Exp Med Biol; 2014; 801():661-7. PubMed ID: 24664756
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Divergent effects of PERK and IRE1 signaling on cell viability.
    Lin JH; Li H; Zhang Y; Ron D; Walter P
    PLoS One; 2009; 4(1):e4170. PubMed ID: 19137072
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival.
    Walter F; Schmid J; Düssmann H; Concannon CG; Prehn JH
    Cell Death Differ; 2015 Sep; 22(9):1502-16. PubMed ID: 25633195
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress.
    Tay KH; Luan Q; Croft A; Jiang CC; Jin L; Zhang XD; Tseng HY
    Cell Signal; 2014 Feb; 26(2):287-94. PubMed ID: 24240056
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
    Merlot AM; Shafie NH; Yu Y; Richardson V; Jansson PJ; Sahni S; Lane DJR; Kovacevic Z; Kalinowski DS; Richardson DR
    Biochem Pharmacol; 2016 Jun; 109():27-47. PubMed ID: 27059255
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ER stress signaling has an activating transcription factor 6α (ATF6)-dependent "off-switch".
    Walter F; O'Brien A; Concannon CG; Düssmann H; Prehn JHM
    J Biol Chem; 2018 Nov; 293(47):18270-18284. PubMed ID: 30287689
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Non-Structural Protein 2B of Human Rhinovirus 16 Activates Both PERK and ATF6 Rather Than IRE1 to Trigger ER Stress.
    Song J; Chi M; Luo X; Song Q; Xia D; Shi B; Han J
    Viruses; 2019 Feb; 11(2):. PubMed ID: 30717233
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway.
    Gjymishka A; Su N; Kilberg MS
    Biochem J; 2009 Feb; 417(3):695-703. PubMed ID: 18840095
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel prosurvival function of Yip1A in human cervical cancer cells: constitutive activation of the IRE1 and PERK pathways of the unfolded protein response.
    Taguchi Y; Horiuchi Y; Kano F; Murata M
    Cell Death Dis; 2017 Mar; 8(3):e2718. PubMed ID: 28358375
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate.
    Chang TK; Lawrence DA; Lu M; Tan J; Harnoss JM; Marsters SA; Liu P; Sandoval W; Martin SE; Ashkenazi A
    Mol Cell; 2018 Aug; 71(4):629-636.e5. PubMed ID: 30118681
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy.
    Liu ZW; Zhu HT; Chen KL; Dong X; Wei J; Qiu C; Xue JH
    Cardiovasc Diabetol; 2013 Nov; 12():158. PubMed ID: 24180212
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.
    Teske BF; Wek SA; Bunpo P; Cundiff JK; McClintick JN; Anthony TG; Wek RC
    Mol Biol Cell; 2011 Nov; 22(22):4390-405. PubMed ID: 21917591
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress.
    DuRose JB; Tam AB; Niwa M
    Mol Biol Cell; 2006 Jul; 17(7):3095-107. PubMed ID: 16672378
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response.
    Gupta A; Hossain MM; Read DE; Hetz C; Samali A; Gupta S
    Sci Rep; 2015 Dec; 5():18304. PubMed ID: 26674075
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Unfolded Protein Response and Cell Fate Control.
    Hetz C; Papa FR
    Mol Cell; 2018 Jan; 69(2):169-181. PubMed ID: 29107536
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IRE1 directs proteasomal and lysosomal degradation of misfolded rhodopsin.
    Chiang WC; Messah C; Lin JH
    Mol Biol Cell; 2012 Mar; 23(5):758-70. PubMed ID: 22219383
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting UPR branches, a potential strategy for enhancing efficacy of cancer chemotherapy.
    Yu M; Lun J; Zhang H; Wang L; Zhang G; Zhang H; Fang J
    Acta Biochim Biophys Sin (Shanghai); 2021 Nov; 53(11):1417-1427. PubMed ID: 34664059
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular Basis of Human Diseases and Targeted Therapy Based on Small-Molecule Inhibitors of ER Stress-Induced Signaling Pathways.
    Rozpedek W; Nowak A; Pytel D; Diehl JA; Majsterek I
    Curr Mol Med; 2017; 17(2):118-132. PubMed ID: 28266275
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 55.