BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

436 related articles for article (PubMed ID: 17991863)

  • 1. GNAT-like strategy for polyketide chain initiation.
    Gu L; Geders TW; Wang B; Gerwick WH; Håkansson K; Smith JL; Sherman DH
    Science; 2007 Nov; 318(5852):970-4. PubMed ID: 17991863
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis.
    Skiba MA; Tran CL; Dan Q; Sikkema AP; Klaver Z; Gerwick WH; Sherman DH; Smith JL
    Structure; 2020 Jan; 28(1):63-74.e4. PubMed ID: 31785925
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching.
    Geders TW; Gu L; Mowers JC; Liu H; Gerwick WH; Håkansson K; Sherman DH; Smith JL
    J Biol Chem; 2007 Dec; 282(49):35954-63. PubMed ID: 17928301
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of molecular interactions between ACP and halogenase domains in the Curacin A polyketide synthase.
    Busche A; Gottstein D; Hein C; Ripin N; Pader I; Tufar P; Eisman EB; Gu L; Walsh CT; Sherman DH; Löhr F; Güntert P; Dötsch V
    ACS Chem Biol; 2012 Feb; 7(2):378-86. PubMed ID: 22103656
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity.
    Florova G; Kazanina G; Reynolds KA
    Biochemistry; 2002 Aug; 41(33):10462-71. PubMed ID: 12173933
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acyl hydrolases from trans-AT polyketide synthases target acetyl units on acyl carrier proteins.
    Jenner M; Afonso JP; Kohlhaas C; Karbaum P; Frank S; Piel J; Oldham NJ
    Chem Commun (Camb); 2016 Apr; 52(30):5262-5. PubMed ID: 27003309
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase.
    Gehret JJ; Gu L; Gerwick WH; Wipf P; Sherman DH; Smith JL
    J Biol Chem; 2011 Apr; 286(16):14445-54. PubMed ID: 21357626
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
    Liou GF; Lau J; Cane DE; Khosla C
    Biochemistry; 2003 Jan; 42(1):200-7. PubMed ID: 12515555
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PanM, an acetyl-coenzyme A sensor required for maturation of L-aspartate decarboxylase (PanD).
    Stuecker TN; Tucker AC; Escalante-Semerena JC
    mBio; 2012; 3(4):. PubMed ID: 22782525
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of the active site of human mitochondrial malonyl-coenzyme a decarboxylase: A combined computational study.
    Ling B; Liu Y; Li X; Wang Z; Bi S
    Proteins; 2016 Jun; 84(6):792-802. PubMed ID: 26948533
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of Helicobacter pylori pseudaminic acid biosynthesis N-acetyltransferase PseH: implications for substrate specificity and catalysis.
    Ud-Din AI; Liu YC; Roujeinikova A
    PLoS One; 2015; 10(3):e0115634. PubMed ID: 25781966
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression and characterization of polyketide synthase module involved in the late step of cephabacin biosynthesis from Lysobacter lactamgenus.
    Lee JS; Vladimirova MG; Demirev AV; Kim BG; Lim SK; Nam DH
    J Microbiol Biotechnol; 2008 Mar; 18(3):427-33. PubMed ID: 18388458
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase.
    Skiba MA; Sikkema AP; Fiers WD; Gerwick WH; Sherman DH; Aldrich CC; Smith JL
    ACS Chem Biol; 2016 Dec; 11(12):3319-3327. PubMed ID: 27723289
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate.
    Maloney FP; Gerwick L; Gerwick WH; Sherman DH; Smith JL
    Proc Natl Acad Sci U S A; 2016 Sep; 113(37):10316-21. PubMed ID: 27573844
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structure of the acyltransferase domain of the iterative polyketide synthase in enediyne biosynthesis.
    Liew CW; Nilsson M; Chen MW; Sun H; Cornvik T; Liang ZX; Lescar J
    J Biol Chem; 2012 Jun; 287(27):23203-15. PubMed ID: 22589546
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB.
    Ma SM; Tang Y
    FEBS J; 2007 Jun; 274(11):2854-64. PubMed ID: 17466016
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module.
    Skiba MA; Sikkema AP; Moss NA; Lowell AN; Su M; Sturgis RM; Gerwick L; Gerwick WH; Sherman DH; Smith JL
    ACS Chem Biol; 2018 Jun; 13(6):1640-1650. PubMed ID: 29701944
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y; Lee TS; Kobayashi S; Khosla C
    Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase.
    Abe I; Watanabe T; Lou W; Noguchi H
    FEBS J; 2006 Jan; 273(1):208-18. PubMed ID: 16367761
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence for a protein-protein interaction motif on an acyl carrier protein domain from a modular polyketide synthase.
    Weissman KJ; Hong H; Popovic B; Meersman F
    Chem Biol; 2006 Jun; 13(6):625-36. PubMed ID: 16793520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.