BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

363 related articles for article (PubMed ID: 17993263)

  • 1. The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway.
    Dance M; Montagner A; Salles JP; Yart A; Raynal P
    Cell Signal; 2008 Mar; 20(3):453-9. PubMed ID: 17993263
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor.
    Easton JB; Royer AR; Middlemas DS
    J Neurochem; 2006 May; 97(3):834-45. PubMed ID: 16573649
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypophosphorylated TCR/CD3zeta signals through a Grb2-SOS1-Ras pathway in Lck knockdown cells.
    Methi T; Ngai J; Vang T; Torgersen KM; Taskén K
    Eur J Immunol; 2007 Sep; 37(9):2539-48. PubMed ID: 17683112
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Beta4 integrin activates a Shp2-Src signaling pathway that sustains HGF-induced anchorage-independent growth.
    Bertotti A; Comoglio PM; Trusolino L
    J Cell Biol; 2006 Dec; 175(6):993-1003. PubMed ID: 17158954
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Three-dimensional matrix induces sustained activation of ERK1/2 via Src/Ras/Raf signaling pathway.
    Damianova R; Stefanova N; Cukierman E; Momchilova A; Pankov R
    Cell Biol Int; 2008 Feb; 32(2):229-34. PubMed ID: 17933561
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Signal strength dictates phosphoinositide 3-kinase contribution to Ras/extracellular signal-regulated kinase 1 and 2 activation via differential Gab1/Shp2 recruitment: consequences for resistance to epidermal growth factor receptor inhibition.
    Sampaio C; Dance M; Montagner A; Edouard T; Malet N; Perret B; Yart A; Salles JP; Raynal P
    Mol Cell Biol; 2008 Jan; 28(2):587-600. PubMed ID: 18025104
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prostaglandin E1 inhibits IL-6-induced MCP-1 expression by interfering specifically in IL-6-dependent ERK1/2, but not STAT3, activation.
    Sobota RM; Müller PJ; Heinrich PC; Schaper F
    Biochem J; 2008 May; 412(1):65-72. PubMed ID: 18271757
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Betagamma subunits of G(i/o) suppress EGF-induced ERK5 phosphorylation, whereas ERK1/2 phosphorylation is enhanced.
    Obara Y; Okano Y; Ono S; Yamauchi A; Hoshino T; Kurose H; Nakahata N
    Cell Signal; 2008 Jul; 20(7):1275-83. PubMed ID: 18407464
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The multi-site docking protein Grb2-associated binder 1 (Gab1) enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner.
    Bongartz H; Gille K; Hessenkemper W; Mandel K; Lewitzky M; Feller SM; Schaper F
    Cell Commun Signal; 2019 Oct; 17(1):135. PubMed ID: 31651330
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of the mitogen-activated protein kinase signaling pathway by SHP2.
    Cunnick JM; Meng S; Ren Y; Desponts C; Wang HG; Djeu JY; Wu J
    J Biol Chem; 2002 Mar; 277(11):9498-504. PubMed ID: 11779868
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Involvement of EphA2-mediated tyrosine phosphorylation of Shp2 in Shp2-regulated activation of extracellular signal-regulated kinase.
    Miura K; Wakayama Y; Tanino M; Orba Y; Sawa H; Hatakeyama M; Tanaka S; Sabe H; Mochizuki N
    Oncogene; 2013 Nov; 32(45):5292-301. PubMed ID: 23318428
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42.
    Rosário M; Franke R; Bednarski C; Birchmeier W
    J Cell Biol; 2007 Jul; 178(3):503-16. PubMed ID: 17664338
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of ACh receptor clustering by the tyrosine phosphatase Shp2.
    Zhao XT; Qian YK; Chan AW; Madhavan R; Peng HB
    Dev Neurobiol; 2007 Nov; 67(13):1789-801. PubMed ID: 17659592
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of the Ras-GTPase activating protein neurofibromin by C-tail phosphorylation: implications for protein kinase C/Ras/extracellular signal-regulated kinase 1/2 pathway signaling and neuronal differentiation.
    Leondaritis G; Petrikkos L; Mangoura D
    J Neurochem; 2009 Apr; 109(2):573-83. PubMed ID: 19220708
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gab2 requires membrane targeting and the Met binding motif to promote lamellipodia, cell scatter, and epithelial morphogenesis downstream from the Met receptor.
    Frigault MM; Naujokas MA; Park M
    J Cell Physiol; 2008 Mar; 214(3):694-705. PubMed ID: 17894413
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein tyrosine phosphatase SHP-2: a proto-oncogene product that promotes Ras activation.
    Matozaki T; Murata Y; Saito Y; Okazawa H; Ohnishi H
    Cancer Sci; 2009 Oct; 100(10):1786-93. PubMed ID: 19622105
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Native and reconstituted HDL activate Stat3 in ventricular cardiomyocytes via ERK1/2: role of sphingosine-1-phosphate.
    Frias MA; James RW; Gerber-Wicht C; Lang U
    Cardiovasc Res; 2009 May; 82(2):313-23. PubMed ID: 19151362
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SHP2 promotes laryngeal cancer growth through the Ras/Raf/Mek/Erk pathway and serves as a prognostic indicator for laryngeal cancer.
    Gu J; Han T; Ma RH; Zhu YL; Jia YN; Du JJ; Chen Y; Jiang XJ; Xie XD; Guo X
    Int J Oncol; 2014 Feb; 44(2):481-90. PubMed ID: 24297342
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth.
    Lee MH; Klein RL; El-Shewy HM; Luttrell DK; Luttrell LM
    Biochemistry; 2008 Nov; 47(44):11682-92. PubMed ID: 18842004
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sprouty2 binds Grb2 at two different proline-rich regions, and the mechanism of ERK inhibition is independent of this interaction.
    Martínez N; García-Domínguez CA; Domingo B; Oliva JL; Zarich N; Sánchez A; Gutiérrez-Eisman S; Llopis J; Rojas JM
    Cell Signal; 2007 Nov; 19(11):2277-85. PubMed ID: 17689925
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.