BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 17994014)

  • 1. Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration.
    Friedman MJ; Shah AG; Fang ZH; Ward EG; Warren ST; Li S; Li XJ
    Nat Neurosci; 2007 Dec; 10(12):1519-28. PubMed ID: 17994014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The indole compound NC009-1 inhibits aggregation and promotes neurite outgrowth through enhancement of HSPB1 in SCA17 cells and ameliorates the behavioral deficits in SCA17 mice.
    Chen CM; Chen WL; Hung CT; Lin TH; Chao CY; Lin CH; Wu YR; Chang KH; Yao CF; Lee-Chen GJ; Su MT; Hsieh-Li HM
    Neurotoxicology; 2018 Jul; 67():259-269. PubMed ID: 29936316
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polyglutamine expansion reduces the association of TATA-binding protein with DNA and induces DNA binding-independent neurotoxicity.
    Friedman MJ; Wang CE; Li XJ; Li S
    J Biol Chem; 2008 Mar; 283(13):8283-90. PubMed ID: 18218637
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor.
    Huang S; Ling JJ; Yang S; Li XJ; Li S
    Brain; 2011 Jul; 134(Pt 7):1943-58. PubMed ID: 21705419
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17.
    Shah AG; Friedman MJ; Huang S; Roberts M; Li XJ; Li S
    Hum Mol Genet; 2009 Nov; 18(21):4141-52. PubMed ID: 19643914
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synergistic Toxicity of Polyglutamine-Expanded TATA-Binding Protein in Glia and Neuronal Cells: Therapeutic Implications for Spinocerebellar Ataxia 17.
    Yang Y; Yang S; Guo J; Cui Y; Tang B; Li XJ; Li S
    J Neurosci; 2017 Sep; 37(38):9101-9115. PubMed ID: 28821675
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deactivation of TBP contributes to SCA17 pathogenesis.
    Hsu TC; Wang CK; Yang CY; Lee LC; Hsieh-Li HM; Ro LS; Chen CM; Lee-Chen GJ; Su MT
    Hum Mol Genet; 2014 Dec; 23(25):6878-93. PubMed ID: 25104854
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular Mechanisms and Therapeutics for SCA17.
    Liu Q; Pan Y; Li XJ; Li S
    Neurotherapeutics; 2019 Oct; 16(4):1097-1105. PubMed ID: 31317427
    [TBL] [Abstract][Full Text] [Related]  

  • 9. microRNA dysregulation in polyglutamine toxicity of TATA-box binding protein is mediated through STAT1 in mouse neuronal cells.
    Roshan R; Choudhary A; Bhambri A; Bakshi B; Ghosh T; Pillai B
    J Neuroinflammation; 2017 Aug; 14(1):155. PubMed ID: 28774347
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of gene transcription by heat shock protein 27 may contribute to its neuronal protection.
    Friedman MJ; Li S; Li XJ
    J Biol Chem; 2009 Oct; 284(41):27944-27951. PubMed ID: 19656944
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of the CCAAT-binding protein NFY in SCA17 pathogenesis.
    Lee LC; Chen CM; Wang HC; Hsieh HH; Chiu IS; Su MT; Hsieh-Li HM; Wu CH; Lee GC; Lee-Chen GJ; Lin JY
    PLoS One; 2012; 7(4):e35302. PubMed ID: 22530004
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cerebellum-enriched protein INPP5A contributes to selective neuropathology in mouse model of spinocerebellar ataxias type 17.
    Liu Q; Huang S; Yin P; Yang S; Zhang J; Jing L; Cheng S; Tang B; Li XJ; Pan Y; Li S
    Nat Commun; 2020 Feb; 11(1):1101. PubMed ID: 32107387
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of the inhibitory DNA-binding surface of human TATA-binding protein in recruitment of human TFIIB family members.
    Zhao X; Herr W
    Mol Cell Biol; 2003 Nov; 23(22):8152-60. PubMed ID: 14585974
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of high mobility group box 1 (HMGB1) in SCA17 pathogenesis.
    Lee LC; Chen CM; Wang PR; Su MT; Lee-Chen GJ; Chang CY
    PLoS One; 2014; 9(12):e115809. PubMed ID: 25549101
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Age-dependent decrease in chaperone activity impairs MANF expression, leading to Purkinje cell degeneration in inducible SCA17 mice.
    Yang S; Huang S; Gaertig MA; Li XJ; Li S
    Neuron; 2014 Jan; 81(2):349-65. PubMed ID: 24462098
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Large Polyglutamine Repeats Cause Muscle Degeneration in SCA17 Mice.
    Huang S; Yang S; Guo J; Yan S; Gaertig MA; Li S; Li XJ
    Cell Rep; 2015 Oct; 13(1):196-208. PubMed ID: 26387956
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular investigation of TBP allele length: a SCA17 cellular model and population study.
    Reid SJ; Rees MI; van Roon-Mom WM; Jones AL; MacDonald ME; Sutherland G; During MJ; Faull RL; Owen MJ; Dragunow M; Snell RG
    Neurobiol Dis; 2003 Jun; 13(1):37-45. PubMed ID: 12758065
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Drosophila model of the neurodegenerative disease SCA17 reveals a role of RBP-J/Su(H) in modulating the pathological outcome.
    Ren J; Jegga AG; Zhang M; Deng J; Liu J; Gordon CB; Aronow BJ; Lu LJ; Zhang B; Ma J
    Hum Mol Genet; 2011 Sep; 20(17):3424-36. PubMed ID: 21653638
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Piperine ameliorates SCA17 neuropathology by reducing ER stress.
    Guo J; Cui Y; Liu Q; Yang Y; Li Y; Weng L; Tang B; Jin P; Li XJ; Yang S; Li S
    Mol Neurodegener; 2018 Jan; 13(1):4. PubMed ID: 29378605
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interdependent interactions between TFIIB, TATA binding protein, and DNA.
    Buratowski RM; Downs J; Buratowski S
    Mol Cell Biol; 2002 Dec; 22(24):8735-43. PubMed ID: 12446790
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.