These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
162 related articles for article (PubMed ID: 17994597)
1. Multispecificity of drug transporters: probing inhibitor selectivity for the human drug efflux transporters ABCB1 and ABCG2. Cramer J; Kopp S; Bates SE; Chiba P; Ecker GF ChemMedChem; 2007 Dec; 2(12):1783-8. PubMed ID: 17994597 [TBL] [Abstract][Full Text] [Related]
2. Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2. Dai CL; Tiwari AK; Wu CP; Su XD; Wang SR; Liu DG; Ashby CR; Huang Y; Robey RW; Liang YJ; Chen LM; Shi CJ; Ambudkar SV; Chen ZS; Fu LW Cancer Res; 2008 Oct; 68(19):7905-14. PubMed ID: 18829547 [TBL] [Abstract][Full Text] [Related]
3. A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry. Strouse JJ; Ivnitski-Steele I; Khawaja HM; Perez D; Ricci J; Yao T; Weiner WS; Schroeder CE; Simpson DS; Maki BE; Li K; Golden JE; Foutz TD; Waller A; Evangelisti AM; Young SM; Chavez SE; Garcia MJ; Ursu O; Bologa CG; Carter MB; Salas VM; Gouveia K; Tegos GP; Oprea TI; Edwards BS; Aubé J; Larson RS; Sklar LA J Biomol Screen; 2013 Jan; 18(1):26-38. PubMed ID: 22923785 [TBL] [Abstract][Full Text] [Related]
4. Nilotinib (AMN107, Tasigna) reverses multidrug resistance by inhibiting the activity of the ABCB1/Pgp and ABCG2/BCRP/MXR transporters. Tiwari AK; Sodani K; Wang SR; Kuang YH; Ashby CR; Chen X; Chen ZS Biochem Pharmacol; 2009 Jul; 78(2):153-61. PubMed ID: 19427995 [TBL] [Abstract][Full Text] [Related]
5. Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters. Fan YF; Zhang W; Zeng L; Lei ZN; Cai CY; Gupta P; Yang DH; Cui Q; Qin ZD; Chen ZS; Trombetta LD Cancer Lett; 2018 May; 421():186-198. PubMed ID: 29331420 [TBL] [Abstract][Full Text] [Related]
6. Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters. Strouse JJ; Ivnitski-Steele I; Waller A; Young SM; Perez D; Evangelisti AM; Ursu O; Bologa CG; Carter MB; Salas VM; Tegos G; Larson RS; Oprea TI; Edwards BS; Sklar LA Anal Biochem; 2013 Jun; 437(1):77-87. PubMed ID: 23470221 [TBL] [Abstract][Full Text] [Related]
7. Inhibiting the function of ABCB1 and ABCG2 by the EGFR tyrosine kinase inhibitor AG1478. Shi Z; Tiwari AK; Shukla S; Robey RW; Kim IW; Parmar S; Bates SE; Si QS; Goldblatt CS; Abraham I; Fu LW; Ambudkar SV; Chen ZS Biochem Pharmacol; 2009 Mar; 77(5):781-93. PubMed ID: 19059384 [TBL] [Abstract][Full Text] [Related]
8. Hedgehog pathway inhibitor HhAntag691 is a potent inhibitor of ABCG2/BCRP and ABCB1/Pgp. Zhang Y; Laterra J; Pomper MG Neoplasia; 2009 Jan; 11(1):96-101. PubMed ID: 19107236 [TBL] [Abstract][Full Text] [Related]
9. Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2. Shukla S; Robey RW; Bates SE; Ambudkar SV Drug Metab Dispos; 2009 Feb; 37(2):359-65. PubMed ID: 18971320 [TBL] [Abstract][Full Text] [Related]
10. Hedgehog signaling regulates drug sensitivity by targeting ABC transporters ABCB1 and ABCG2 in epithelial ovarian cancer. Chen Y; Bieber MM; Teng NN Mol Carcinog; 2014 Aug; 53(8):625-34. PubMed ID: 23423781 [TBL] [Abstract][Full Text] [Related]
11. The "specific" P-glycoprotein inhibitor Tariquidar is also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2). Kannan P; Telu S; Shukla S; Ambudkar SV; Pike VW; Halldin C; Gottesman MM; Innis RB; Hall MD ACS Chem Neurosci; 2011 Feb; 2(2):82-9. PubMed ID: 22778859 [TBL] [Abstract][Full Text] [Related]
12. Karanjin interferes with ABCB1, ABCC1, and ABCG2. Michaelis M; Rothweiler F; Nerreter T; Sharifi M; Ghafourian T; Cinatl J J Pharm Pharm Sci; 2014; 17(1):92-105. PubMed ID: 24735762 [TBL] [Abstract][Full Text] [Related]
13. ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis. Cotte S; von Ahsen N; Kruse N; Huber B; Winkelmann A; Zettl UK; Starck M; König N; Tellez N; Dörr J; Paul F; Zipp F; Lühder F; Koepsell H; Pannek H; Montalban X; Gold R; Chan A Brain; 2009 Sep; 132(Pt 9):2517-30. PubMed ID: 19605531 [TBL] [Abstract][Full Text] [Related]
14. Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance. Shi Z; Peng XX; Kim IW; Shukla S; Si QS; Robey RW; Bates SE; Shen T; Ashby CR; Fu LW; Ambudkar SV; Chen ZS Cancer Res; 2007 Nov; 67(22):11012-20. PubMed ID: 18006847 [TBL] [Abstract][Full Text] [Related]
15. Interaction potential of etravirine with drug transporters assessed in vitro. Zembruski NC; Haefeli WE; Weiss J Antimicrob Agents Chemother; 2011 Mar; 55(3):1282-4. PubMed ID: 21189339 [TBL] [Abstract][Full Text] [Related]
16. In silico prediction of substrate properties for ABC-multidrug transporters. Demel MA; Schwaha R; Krämer O; Ettmayer P; Haaksma EE; Ecker GF Expert Opin Drug Metab Toxicol; 2008 Sep; 4(9):1167-80. PubMed ID: 18721111 [TBL] [Abstract][Full Text] [Related]
17. Rapid detection of ABC transporter interaction: potential utility in pharmacology. Robey RW; Lin B; Qiu J; Chan LL; Bates SE J Pharmacol Toxicol Methods; 2011; 63(3):217-22. PubMed ID: 21112407 [TBL] [Abstract][Full Text] [Related]
18. Olomoucine II, but not purvalanol A, is transported by breast cancer resistance protein (ABCG2) and P-glycoprotein (ABCB1). Hofman J; Kučera R; Cihalova D; Klimes J; Ceckova M; Staud F PLoS One; 2013; 8(10):e75520. PubMed ID: 24116053 [TBL] [Abstract][Full Text] [Related]
19. Pharmacophore modeling of nilotinib as an inhibitor of ATP-binding cassette drug transporters and BCR-ABL kinase using a three-dimensional quantitative structure-activity relationship approach. Shukla S; Kouanda A; Silverton L; Talele TT; Ambudkar SV Mol Pharm; 2014 Jul; 11(7):2313-22. PubMed ID: 24865254 [TBL] [Abstract][Full Text] [Related]
20. Overlapping substrate and inhibitor specificity of human and murine ABCG2. Bakhsheshian J; Hall MD; Robey RW; Herrmann MA; Chen JQ; Bates SE; Gottesman MM Drug Metab Dispos; 2013 Oct; 41(10):1805-12. PubMed ID: 23868912 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]