BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 17996499)

  • 1. Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas.
    Nammo T; Yamagata K; Tanaka T; Kodama T; Sladek FM; Fukui K; Katsube F; Sato Y; Miyagawa J; Shimomura I
    Gene Expr Patterns; 2008 Jan; 8(2):96-106. PubMed ID: 17996499
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutation screening in 18 Caucasian families suggest the existence of other MODY genes.
    Chèvre JC; Hani EH; Boutin P; Vaxillaire M; Blanché H; Vionnet N; Pardini VC; Timsit J; Larger E; Charpentier G; Beckers D; Maes M; Bellanné-Chantelot C; Velho G; Froguel P
    Diabetologia; 1998 Sep; 41(9):1017-23. PubMed ID: 9754819
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression profile of MODY3/HNF-1alpha protein in the developing mouse pancreas.
    Nammo T; Yamagata K; Hamaoka R; Zhu Q; Akiyama TE; Gonzalez FJ; Miyagawa J; Matsuzawa Y
    Diabetologia; 2002 Aug; 45(8):1142-53. PubMed ID: 12189445
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in GCK and HNF-1alpha explain the majority of cases with clinical diagnosis of MODY in Spain.
    Estalella I; Rica I; Perez de Nanclares G; Bilbao JR; Vazquez JA; San Pedro JI; Busturia MA; Castaño L;
    Clin Endocrinol (Oxf); 2007 Oct; 67(4):538-46. PubMed ID: 17573900
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels.
    Richter S; Shih DQ; Pearson ER; Wolfrum C; Fajans SS; Hattersley AT; Stoffel M
    Diabetes; 2003 Dec; 52(12):2989-95. PubMed ID: 14633861
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function.
    Hansen SK; Párrizas M; Jensen ML; Pruhova S; Ek J; Boj SF; Johansen A; Maestro MA; Rivera F; Eiberg H; Andel M; Lebl J; Pedersen O; Ferrer J; Hansen T
    J Clin Invest; 2002 Sep; 110(6):827-33. PubMed ID: 12235114
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4alpha, GCK and HNF-1alpha.
    Pruhova S; Ek J; Lebl J; Sumnik Z; Saudek F; Andel M; Pedersen O; Hansen T
    Diabetologia; 2003 Feb; 46(2):291-5. PubMed ID: 12627330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel Phe75fsdelT mutation in the hepatocyte nuclear factor-4alpha gene in a Danish pedigree with maturity-onset diabetes of the young.
    Møller AM; Dalgaard LT; Ambye L; Hansen L; Schmitz O; Hansen T; Pedersen O
    J Clin Endocrinol Metab; 1999 Jan; 84(1):367-9. PubMed ID: 9920109
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanisms of mutual functional interactions between HNF-4alpha and HNF-1alpha revealed by mutations that cause maturity onset diabetes of the young.
    Rowley CW; Staloch LJ; Divine JK; McCaul SP; Simon TC
    Am J Physiol Gastrointest Liver Physiol; 2006 Mar; 290(3):G466-75. PubMed ID: 16223942
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians.
    Baier LJ; Permana PA; Traurig M; Dobberfuhl A; Wiedrich C; Sutherland J; Thuillez P; Luczy-Bachman G; Hara M; Horikawa Y; Hinokio Y; Hanson RL; Bogardus C
    Diabetes Care; 2000 Mar; 23(3):302-4. PubMed ID: 10868855
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1).
    Yamagata K; Furuta H; Oda N; Kaisaki PJ; Menzel S; Cox NJ; Fajans SS; Signorini S; Stoffel M; Bell GI
    Nature; 1996 Dec; 384(6608):458-60. PubMed ID: 8945471
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young.
    Thomas H; Jaschkowitz K; Bulman M; Frayling TM; Mitchell SM; Roosen S; Lingott-Frieg A; Tack CJ; Ellard S; Ryffel GU; Hattersley AT
    Hum Mol Genet; 2001 Sep; 10(19):2089-97. PubMed ID: 11590126
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular genetic analysis of MODY candidate genes in Japanese patients with non-obese juvenile onset diabetes mellitus.
    Kagami-Takasugi M; Katsumata N; Tanaka T; Tajima T; Fujieda K
    J Pediatr Endocrinol Metab; 2006 Feb; 19(2):143-8. PubMed ID: 16562587
    [TBL] [Abstract][Full Text] [Related]  

  • 14. beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors.
    Frayling TM; Evans JC; Bulman MP; Pearson E; Allen L; Owen K; Bingham C; Hannemann M; Shepherd M; Ellard S; Hattersley AT
    Diabetes; 2001 Feb; 50 Suppl 1():S94-100. PubMed ID: 11272211
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional study of the E276Q mutant hepatocyte nuclear factor-4alpha found in type 1 maturity-onset diabetes of the young: impaired synergy with chicken ovalbumin upstream promoter transcription factor II on the hepatocyte nuclear factor-1 promoter.
    Suaud L; Hemimou Y; Formstecher P; Laine B
    Diabetes; 1999 May; 48(5):1162-7. PubMed ID: 10331424
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes.
    Holmkvist J; Almgren P; Lyssenko V; Lindgren CM; Eriksson KF; Isomaa B; Tuomi T; Nilsson P; Groop L
    Diabetes; 2008 Jun; 57(6):1738-44. PubMed ID: 18332101
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutant HNF-1alpha and mutant HNF-1beta identified in MODY3 and MODY5 downregulate DPP-IV gene expression in Caco-2 cells.
    Gu N; Adachi T; Matsunaga T; Takeda J; Tsujimoto G; Ishihara A; Yasuda K; Tsuda K
    Biochem Biophys Res Commun; 2006 Aug; 346(3):1016-23. PubMed ID: 16781669
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A genetic switch in pancreatic beta-cells: implications for differentiation and haploinsufficiency.
    Ferrer J
    Diabetes; 2002 Aug; 51(8):2355-62. PubMed ID: 12145145
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene.
    Lindner T; Gragnoli C; Furuta H; Cockburn BN; Petzold C; Rietzsch H; Weiss U; Schulze J; Bell GI
    J Clin Invest; 1997 Sep; 100(6):1400-5. PubMed ID: 9294105
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genetic and clinical characteristics of Korean maturity-onset diabetes of the young (MODY) patients.
    Hwang JS; Shin CH; Yang SW; Jung SY; Huh N
    Diabetes Res Clin Pract; 2006 Oct; 74(1):75-81. PubMed ID: 16632067
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.