109 related articles for article (PubMed ID: 17998065)
21. Combination strategy targeting the hypoxia inducible factor-1 alpha with mammalian target of rapamycin and histone deacetylase inhibitors.
Verheul HM; Salumbides B; Van Erp K; Hammers H; Qian DZ; Sanni T; Atadja P; Pili R
Clin Cancer Res; 2008 Jun; 14(11):3589-97. PubMed ID: 18519793
[TBL] [Abstract][Full Text] [Related]
22. Reactive oxygen species and HIF-1 signalling in cancer.
Galanis A; Pappa A; Giannakakis A; Lanitis E; Dangaj D; Sandaltzopoulos R
Cancer Lett; 2008 Jul; 266(1):12-20. PubMed ID: 18378391
[TBL] [Abstract][Full Text] [Related]
23. The human HIF (hypoxia-inducible factor)-3alpha gene is a HIF-1 target gene and may modulate hypoxic gene induction.
Tanaka T; Wiesener M; Bernhardt W; Eckardt KU; Warnecke C
Biochem J; 2009 Oct; 424(1):143-51. PubMed ID: 19694616
[TBL] [Abstract][Full Text] [Related]
24. Impact of cyclic hypoxia on HIF-1alpha regulation in endothelial cells--new insights for anti-tumor treatments.
Martinive P; Defresne F; Quaghebeur E; Daneau G; Crokart N; Grégoire V; Gallez B; Dessy C; Feron O
FEBS J; 2009 Jan; 276(2):509-18. PubMed ID: 19077164
[TBL] [Abstract][Full Text] [Related]
25. CCAAT/enhancer-binding protein alpha antagonizes transcriptional activity of hypoxia-inducible factor 1 alpha with direct protein-protein interaction.
Yang L; Jiang Y; Wu SF; Zhou MY; Wu YL; Chen GQ
Carcinogenesis; 2008 Feb; 29(2):291-8. PubMed ID: 18024476
[TBL] [Abstract][Full Text] [Related]
26. Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1 alpha-deficient mouse embryonic fibroblasts.
Wirthner R; Wrann S; Balamurugan K; Wenger RH; Stiehl DP
Carcinogenesis; 2008 Dec; 29(12):2306-16. PubMed ID: 18842680
[TBL] [Abstract][Full Text] [Related]
27. The contemporary drug development process: advances and challenges in preclinical and clinical development.
Garrett MD; Walton MI; McDonald E; Judson I; Workman P
Prog Cell Cycle Res; 2003; 5():145-58. PubMed ID: 14593708
[TBL] [Abstract][Full Text] [Related]
28. Dexamethasone impairs hypoxia-inducible factor-1 function.
Wagner AE; Huck G; Stiehl DP; Jelkmann W; Hellwig-Bürgel T
Biochem Biophys Res Commun; 2008 Jul; 372(2):336-40. PubMed ID: 18501194
[TBL] [Abstract][Full Text] [Related]
29. Hypoxia-inducible factor 1 as a possible target for cancer chemoprevention.
López-Lázaro M
Cancer Epidemiol Biomarkers Prev; 2006 Dec; 15(12):2332-5. PubMed ID: 17164353
[TBL] [Abstract][Full Text] [Related]
30. Inhibitors of hypoxia-inducible factor-1 signaling.
Belozerov VE; Van Meir EG
Curr Opin Investig Drugs; 2006 Dec; 7(12):1067-76. PubMed ID: 17209524
[TBL] [Abstract][Full Text] [Related]
31. The mighty mouse: genetically engineered mouse models in cancer drug development.
Sharpless NE; Depinho RA
Nat Rev Drug Discov; 2006 Sep; 5(9):741-54. PubMed ID: 16915232
[TBL] [Abstract][Full Text] [Related]
32. The search for novel drug leads for predominately antitumor therapies by utilizing mother nature's pharmacophoric libraries.
Kingston DG; Newman DJ
Curr Opin Drug Discov Devel; 2005 Mar; 8(2):207-27. PubMed ID: 15782545
[TBL] [Abstract][Full Text] [Related]
33. Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors.
Nagao S; Yamane Y; Funasaka S; Tanaka K; Miyazaki K; Kotake Y; Kamata J; Watanabe-Miyano S; Toyama O; Ozawa Y; Mizui Y; Okamoto K; Ito D
Bioorg Med Chem; 2014 Oct; 22(19):5513-29. PubMed ID: 25139751
[TBL] [Abstract][Full Text] [Related]
34. Natural product-based inhibitors of hypoxia-inducible factor-1 (HIF-1).
Nagle DG; Zhou YD
Curr Drug Targets; 2006 Mar; 7(3):355-69. PubMed ID: 16515532
[TBL] [Abstract][Full Text] [Related]
35. Benzochromenones from the marine crinoid Comantheria rotula inhibit hypoxia-inducible factor-1 (HIF-1) in cell-based reporter assays and differentially suppress the growth of certain tumor cell lines.
Dai J; Liu Y; Jia H; Zhou YD; Nagle DG
J Nat Prod; 2007 Sep; 70(9):1462-6. PubMed ID: 17844994
[TBL] [Abstract][Full Text] [Related]
36. Molecular-targeted antitumor agents. 15. Neolamellarins from the marine sponge Dendrilla nigra inhibit hypoxia-inducible factor-1 activation and secreted vascular endothelial growth factor production in breast tumor cells.
Liu R; Liu Y; Zhou YD; Nagle DG
J Nat Prod; 2007 Nov; 70(11):1741-5. PubMed ID: 17958397
[TBL] [Abstract][Full Text] [Related]
37. Targeting hypoxia-inducible factor-1, for cancer treatment: Recent advances in developing small-molecule inhibitors from natural compounds.
Ma Z; Xiang X; Li S; Xie P; Gong Q; Goh BC; Wang L
Semin Cancer Biol; 2022 May; 80():379-390. PubMed ID: 33002608
[TBL] [Abstract][Full Text] [Related]
38. Interrelationships among hypoxia-inducible factor biology and acid-base equilibrium.
Hulter HN; Krapf R
Semin Nephrol; 2006 Nov; 26(6):454-65. PubMed ID: 17275583
[TBL] [Abstract][Full Text] [Related]
39. Targeting the hypoxia pathway to treat pancreatic cancer.
Erickson LA; Highsmith WE; Fei P; Zhang J
Drug Des Devel Ther; 2015; 9():2029-31. PubMed ID: 25897209
[TBL] [Abstract][Full Text] [Related]
40. Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy.
Ikeda H; Kakeya H
J Antibiot (Tokyo); 2021 Oct; 74(10):687-695. PubMed ID: 34331027
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
