172 related articles for article (PubMed ID: 18000394)
1. Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy.
Gills JJ; Lopiccolo J; Dennis PA
Autophagy; 2008 Jan; 4(1):107-9. PubMed ID: 18000394
[TBL] [Abstract][Full Text] [Related]
2. Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo.
Gills JJ; Lopiccolo J; Tsurutani J; Shoemaker RH; Best CJ; Abu-Asab MS; Borojerdi J; Warfel NA; Gardner ER; Danish M; Hollander MC; Kawabata S; Tsokos M; Figg WD; Steeg PS; Dennis PA
Clin Cancer Res; 2007 Sep; 13(17):5183-94. PubMed ID: 17785575
[TBL] [Abstract][Full Text] [Related]
3. The HIV protease inhibitor nelfinavir down-regulates RET signaling and induces apoptosis in medullary thyroid cancer cells.
Kushchayeva Y; Jensen K; Recupero A; Costello J; Patel A; Klubo-Gwiezdzinska J; Boyle L; Burman K; Vasko V
J Clin Endocrinol Metab; 2014 May; 99(5):E734-45. PubMed ID: 24483157
[TBL] [Abstract][Full Text] [Related]
4. Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells.
Brüning A; Friese K; Burges A; Mylonas I
Breast Cancer Res; 2010; 12(4):R45. PubMed ID: 20594311
[TBL] [Abstract][Full Text] [Related]
5. Nelfinavir and bortezomib inhibit mTOR activity via ATF4-mediated sestrin-2 regulation.
Brüning A; Rahmeh M; Friese K
Mol Oncol; 2013 Dec; 7(6):1012-8. PubMed ID: 23916134
[TBL] [Abstract][Full Text] [Related]
6. Ritonavir, nelfinavir, saquinavir and lopinavir induce proteotoxic stress in acute myeloid leukemia cells and sensitize them for proteasome inhibitor treatment at low micromolar drug concentrations.
Kraus M; Müller-Ide H; Rückrich T; Bader J; Overkleeft H; Driessen C
Leuk Res; 2014 Mar; 38(3):383-92. PubMed ID: 24418752
[TBL] [Abstract][Full Text] [Related]
7. Nelfinavir inhibits proliferation and induces DNA damage in thyroid cancer cells.
Jensen K; Bikas A; Patel A; Kushchayeva Y; Costello J; McDaniel D; Burman K; Vasko V
Endocr Relat Cancer; 2017 Mar; 24(3):147-156. PubMed ID: 28137980
[TBL] [Abstract][Full Text] [Related]
8. HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress.
Pyrko P; Kardosh A; Wang W; Xiong W; Schönthal AH; Chen TC
Cancer Res; 2007 Nov; 67(22):10920-8. PubMed ID: 18006837
[TBL] [Abstract][Full Text] [Related]
9. HIV protease inhibitor nelfinavir inhibits growth of human melanoma cells by induction of cell cycle arrest.
Jiang W; Mikochik PJ; Ra JH; Lei H; Flaherty KT; Winkler JD; Spitz FR
Cancer Res; 2007 Feb; 67(3):1221-7. PubMed ID: 17283158
[TBL] [Abstract][Full Text] [Related]
10. Nelfinavir inhibits regulated intramembrane proteolysis of sterol regulatory element binding protein-1 and activating transcription factor 6 in castration-resistant prostate cancer.
Guan M; Fousek K; Chow WA
FEBS J; 2012 Jul; 279(13):2399-411. PubMed ID: 22540830
[TBL] [Abstract][Full Text] [Related]
11. Panobinostat and Nelfinavir Inhibit Renal Cancer Growth by Inducing Endoplasmic Reticulum Stress.
Okubo K; Isono M; Asano T; Sato A
Anticancer Res; 2018 Oct; 38(10):5615-5626. PubMed ID: 30275179
[TBL] [Abstract][Full Text] [Related]
12. The HIV protease inhibitor nelfinavir downregulates Akt phosphorylation by inhibiting proteasomal activity and inducing the unfolded protein response.
Gupta AK; Li B; Cerniglia GJ; Ahmed MS; Hahn SM; Maity A
Neoplasia; 2007 Apr; 9(4):271-8. PubMed ID: 17460771
[TBL] [Abstract][Full Text] [Related]
13. Nanotechnology Based Repositioning of an Anti-Viral Drug for Non-Small Cell Lung Cancer (NSCLC).
Parvathaneni V; Goyal M; Kulkarni NS; Shukla SK; Gupta V
Pharm Res; 2020 Jun; 37(7):123. PubMed ID: 32514688
[TBL] [Abstract][Full Text] [Related]
14. Nelfinavir induces liposarcoma apoptosis and cell cycle arrest by upregulating sterol regulatory element binding protein-1.
Chow WA; Guo S; Valdes-Albini F
Anticancer Drugs; 2006 Sep; 17(8):891-903. PubMed ID: 16940799
[TBL] [Abstract][Full Text] [Related]
15. Validation and toxicity of PI3K/Akt pathway inhibition by HIV protease inhibitors in humans.
Plastaras JP; Vapiwala N; Ahmed MS; Gudonis D; Cerniglia GJ; Feldman MD; Frank I; Gupta AK
Cancer Biol Ther; 2008 May; 7(5):628-35. PubMed ID: 18285707
[TBL] [Abstract][Full Text] [Related]
16. HIV protease inhibitors block Akt signaling and radiosensitize tumor cells both in vitro and in vivo.
Gupta AK; Cerniglia GJ; Mick R; McKenna WG; Muschel RJ
Cancer Res; 2005 Sep; 65(18):8256-65. PubMed ID: 16166302
[TBL] [Abstract][Full Text] [Related]
17. The HIV protease inhibitor saquinavir induces endoplasmic reticulum stress, autophagy, and apoptosis in ovarian cancer cells.
McLean K; VanDeVen NA; Sorenson DR; Daudi S; Liu JR
Gynecol Oncol; 2009 Mar; 112(3):623-30. PubMed ID: 19147209
[TBL] [Abstract][Full Text] [Related]
18. Alterations in the Notch4 pathway in cerebral endothelial cells by the HIV aspartyl protease inhibitor, nelfinavir.
Grigorian A; Hurford R; Chao Y; Patrick C; Langford TD
BMC Neurosci; 2008 Feb; 9():27. PubMed ID: 18302767
[TBL] [Abstract][Full Text] [Related]
19. Human immunodeficiency virus protease inhibitors interact with ATP binding cassette transporter 4/multidrug resistance protein 4: a basis for unanticipated enhanced cytotoxicity.
Fukuda Y; Takenaka K; Sparreboom A; Cheepala SB; Wu CP; Ekins S; Ambudkar SV; Schuetz JD
Mol Pharmacol; 2013 Sep; 84(3):361-71. PubMed ID: 23775562
[TBL] [Abstract][Full Text] [Related]
20. Nelfinavir and Ritonavir Kill Bladder Cancer Cells Synergistically by Inducing Endoplasmic Reticulum Stress.
Sato A; Asano T; Okubo K; Isono M; Asano T
Oncol Res; 2018 Mar; 26(2):323-332. PubMed ID: 28560953
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
