BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

464 related articles for article (PubMed ID: 18005249)

  • 1. Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice.
    Ramsey KM; Mills KF; Satoh A; Imai S
    Aging Cell; 2008 Jan; 7(1):78-88. PubMed ID: 18005249
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice.
    Moynihan KA; Grimm AA; Plueger MM; Bernal-Mizrachi E; Ford E; Cras-Méneur C; Permutt MA; Imai S
    Cell Metab; 2005 Aug; 2(2):105-17. PubMed ID: 16098828
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells.
    Bordone L; Motta MC; Picard F; Robinson A; Jhala US; Apfeld J; McDonagh T; Lemieux M; McBurney M; Szilvasi A; Easlon EJ; Lin SJ; Guarente L
    PLoS Biol; 2006 Feb; 4(2):e31. PubMed ID: 16366736
    [TBL] [Abstract][Full Text] [Related]  

  • 4. WldS enhances insulin transcription and secretion via a SIRT1-dependent pathway and improves glucose homeostasis.
    Wu J; Zhang F; Yan M; Wu D; Yu Q; Zhang Y; Zhou B; McBurney MW; Zhai Q
    Diabetes; 2011 Dec; 60(12):3197-207. PubMed ID: 21998399
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nicotinamide mononucleotide promotes pancreatic islet function through the SIRT1 pathway in mice after severe burns.
    Liu X; Li D; Liu Z; Song Y; Zhang B; Zang Y; Zhang W; Niu Y; Shen C
    Burns; 2022 Dec; 48(8):1922-1932. PubMed ID: 35123833
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice.
    Seshadri N; Jonasson ME; Hunt KL; Xiang B; Cooper S; Wheeler MB; Dolinsky VW; Doucette CA
    Mol Metab; 2017 Jul; 6(7):760-769. PubMed ID: 28702331
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion.
    Robson-Doucette CA; Sultan S; Allister EM; Wikstrom JD; Koshkin V; Bhattacharjee A; Prentice KJ; Sereda SB; Shirihai OS; Wheeler MB
    Diabetes; 2011 Nov; 60(11):2710-9. PubMed ID: 21984579
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overexpression of short heterodimer partner recovers impaired glucose-stimulated insulin secretion of pancreatic beta-cells overexpressing UCP2.
    Suh YH; Kim SY; Lee HY; Jang BC; Bae JH; Sohn JN; Bae JH; Suh SI; Park JW; Lee KU; Song DK
    J Endocrinol; 2004 Oct; 183(1):133-44. PubMed ID: 15525581
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endogenous islet uncoupling protein-2 expression and loss of glucose homeostasis in ob/ob mice.
    Saleh MC; Wheeler MB; Chan CB
    J Endocrinol; 2006 Sep; 190(3):659-67. PubMed ID: 17003267
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.
    Joseph JW; Koshkin V; Saleh MC; Sivitz WI; Zhang CY; Lowell BB; Chan CB; Wheeler MB
    J Biol Chem; 2004 Dec; 279(49):51049-56. PubMed ID: 15448158
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in β-cells.
    Lee J; Kim MS; Li R; Liu VY; Fu L; Moore DD; Ma K; Yechoor VK
    Islets; 2011; 3(6):381-8. PubMed ID: 22045262
    [TBL] [Abstract][Full Text] [Related]  

  • 12. cAMP-mediated signaling normalizes glucose-stimulated insulin secretion in uncoupling protein-2 overexpressing beta-cells.
    McQuaid TS; Saleh MC; Joseph JW; Gyulkhandanyan A; Manning-Fox JE; MacLellan JD; Wheeler MB; Chan CB
    J Endocrinol; 2006 Sep; 190(3):669-80. PubMed ID: 17003268
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The hydrolase DDAH2 enhances pancreatic insulin secretion by transcriptional regulation of secretagogin through a Sirt1-dependent mechanism in mice.
    Hasegawa K; Wakino S; Kimoto M; Minakuchi H; Fujimura K; Hosoya K; Komatsu M; Kaneko Y; Kanda T; Tokuyama H; Hayashi K; Itoh H
    FASEB J; 2013 Jun; 27(6):2301-15. PubMed ID: 23430976
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A SIRTain role in pancreatic beta cell function.
    Leibiger IB; Berggren PO
    Cell Metab; 2005 Aug; 2(2):80-2. PubMed ID: 16098824
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice.
    Yoshino J; Mills KF; Yoon MJ; Imai S
    Cell Metab; 2011 Oct; 14(4):528-36. PubMed ID: 21982712
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.
    Bensellam M; Shi YC; Chan JY; Laybutt DR; Chae H; Abou-Samra M; Pappas EG; Thomas HE; Gilon P; Jonas JC
    Diabetologia; 2019 Dec; 62(12):2273-2286. PubMed ID: 31624901
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Perfluorooctane sulfonate continual exposure impairs glucose-stimulated insulin secretion via SIRT1-induced upregulation of UCP2 expression.
    Duan X; Sun W; Sun H; Zhang L
    Environ Pollut; 2021 Jun; 278():116840. PubMed ID: 33689947
    [TBL] [Abstract][Full Text] [Related]  

  • 18. UCP2 mRNA expression is dependent on glucose metabolism in pancreatic islets.
    Dalgaard LT
    Biochem Biophys Res Commun; 2012 Jan; 417(1):495-500. PubMed ID: 22177951
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme.
    Revollo JR; Körner A; Mills KF; Satoh A; Wang T; Garten A; Dasgupta B; Sasaki Y; Wolberger C; Townsend RR; Milbrandt J; Kiess W; Imai S
    Cell Metab; 2007 Nov; 6(5):363-75. PubMed ID: 17983582
    [TBL] [Abstract][Full Text] [Related]  

  • 20. β-Cell-specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice.
    Huynh FK; Peterson BS; Anderson KA; Lin Z; Coakley AJ; Llaguno FMS; Nguyen TN; Campbell JE; Stephens SB; Newgard CB; Hirschey MD
    Am J Physiol Endocrinol Metab; 2020 Oct; 319(4):E805-E813. PubMed ID: 32865009
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.