BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 18006502)

  • 21. Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.
    Blalock WL; Navolanic PM; Steelman LS; Shelton JG; Moye PW; Lee JT; Franklin RA; Mirza A; McMahon M; White MK; McCubrey JA
    Leukemia; 2003 Jun; 17(6):1058-67. PubMed ID: 12764369
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells.
    Shelton JG; Steelman LS; Lee JT; Knapp SL; Blalock WL; Moye PW; Franklin RA; Pohnert SC; Mirza AM; McMahon M; McCubrey JA
    Oncogene; 2003 Apr; 22(16):2478-92. PubMed ID: 12717425
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Human intestinal epithelial crypt cell survival and death: Complex modulations of Bcl-2 homologs by Fak, PI3-K/Akt-1, MEK/Erk, and p38 signaling pathways.
    Harnois C; Demers MJ; Bouchard V; Vallée K; Gagné D; Fujita N; Tsuruo T; Vézina A; Beaulieu JF; Côté A; Vachon PH
    J Cell Physiol; 2004 Feb; 198(2):209-22. PubMed ID: 14603523
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Oncogenic B-RafV600E inhibits apoptosis and promotes ERK-dependent inactivation of Bad and Bim.
    Sheridan C; Brumatti G; Martin SJ
    J Biol Chem; 2008 Aug; 283(32):22128-35. PubMed ID: 18508762
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Sublytic C5b-9-stimulated Schwann cell survival through PI 3-kinase-mediated phosphorylation of BAD.
    Hila S; Soane L; Koski CL
    Glia; 2001 Oct; 36(1):58-67. PubMed ID: 11571784
    [TBL] [Abstract][Full Text] [Related]  

  • 26. CD166 positively regulates MCAM via inhibition to ubiquitin E3 ligases Smurf1 and βTrCP through PI3K/AKT and c-Raf/MEK/ERK signaling in Bel-7402 hepatocellular carcinoma cells.
    Tang X; Chen X; Xu Y; Qiao Y; Zhang X; Wang Y; Guan Y; Sun F; Wang J
    Cell Signal; 2015 Sep; 27(9):1694-702. PubMed ID: 26004137
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade.
    Lee YI; Kang-Park S; Do SI; Lee YI
    J Biol Chem; 2001 May; 276(20):16969-77. PubMed ID: 11278872
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Involvement of smad2 and Erk/Akt cascade in TGF-β1-induced apoptosis in human gingival epithelial cells.
    Yoshimoto T; Fujita T; Kajiya M; Matsuda S; Ouhara K; Shiba H; Kurihara H
    Cytokine; 2015 Sep; 75(1):165-73. PubMed ID: 25882870
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Integrins regulate microtubule nucleating activity of centrosome through mitogen-activated protein kinase/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase (MEK/ERK) signaling.
    Colello D; Mathew S; Ward R; Pumiglia K; LaFlamme SE
    J Biol Chem; 2012 Jan; 287(4):2520-30. PubMed ID: 22117069
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma.
    Guenther MK; Graab U; Fulda S
    Cancer Lett; 2013 Sep; 337(2):200-9. PubMed ID: 23684925
    [TBL] [Abstract][Full Text] [Related]  

  • 31. NSK-01105 inhibits proliferation and induces apoptosis of prostate cancer cells by blocking the Raf/MEK/ERK and PI3K/Akt/mTOR signal pathways.
    Yu P; Ye L; Wang H; Du G; Zhang J; Zhang J; Tian J
    Tumour Biol; 2015 Mar; 36(3):2143-53. PubMed ID: 25398692
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
    McCubrey JA; Steelman LS; Abrams SL; Lee JT; Chang F; Bertrand FE; Navolanic PM; Terrian DM; Franklin RA; D'Assoro AB; Salisbury JL; Mazzarino MC; Stivala F; Libra M
    Adv Enzyme Regul; 2006; 46():249-79. PubMed ID: 16854453
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.
    Ulivi P; Arienti C; Amadori D; Fabbri F; Carloni S; Tesei A; Vannini I; Silvestrini R; Zoli W
    J Cell Physiol; 2009 Jul; 220(1):214-21. PubMed ID: 19288493
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated protein kinase pathway and the Akt pathway.
    Siwak DR; Shishodia S; Aggarwal BB; Kurzrock R
    Cancer; 2005 Aug; 104(4):879-90. PubMed ID: 16007726
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Grb10 and active Raf-1 kinase promote Bad-dependent cell survival.
    Kebache S; Ash J; Annis MG; Hagan J; Huber M; Hassard J; Stewart CL; Whiteway M; Nantel A
    J Biol Chem; 2007 Jul; 282(30):21873-83. PubMed ID: 17535812
    [TBL] [Abstract][Full Text] [Related]  

  • 36. SODD Promotes Lung Cancer Tumorigenesis by Activating the PDK1/AKT and RAF/MEK/ERK Signaling.
    Bao F; An S; Yang Y; Xu TR
    Genes (Basel); 2023 Mar; 14(4):. PubMed ID: 37107587
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad.
    Shimamura H; Terada Y; Okado T; Tanaka H; Inoshita S; Sasaki S
    J Am Soc Nephrol; 2003 Jun; 14(6):1427-34. PubMed ID: 12761242
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt.
    Fernando RI; Wimalasena J
    Mol Biol Cell; 2004 Jul; 15(7):3266-84. PubMed ID: 15121878
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Activation of RAF/MEK/ERK and PI3K/AKT/mTOR pathways in pituitary adenomas and their effects on downstream effectors.
    Dworakowska D; Wlodek E; Leontiou CA; Igreja S; Cakir M; Teng M; Prodromou N; Góth MI; Grozinsky-Glasberg S; Gueorguiev M; Kola B; Korbonits M; Grossman AB
    Endocr Relat Cancer; 2009 Dec; 16(4):1329-38. PubMed ID: 19620247
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Leukemia inhibitory factor can mediate Ras/Raf/MEK/ERK-induced growth inhibitory signaling in medullary thyroid cancer cells.
    Arthan D; Hong SK; Park JI
    Cancer Lett; 2010 Nov; 297(1):31-41. PubMed ID: 20570039
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.