These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 18007605)

  • 1. Synthesis of a fluorescent analogue of geranylgeranyl pyrophosphate and its use in a high-throughput fluorometric assay for Rab geranylgeranyltransferase.
    Wu YW; Alexandrov K; Brunsveld L
    Nat Protoc; 2007; 2(11):2704-11. PubMed ID: 18007605
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification and specificity profiling of protein prenyltransferase inhibitors using new fluorescent phosphoisoprenoids.
    Dursina B; Reents R; Delon C; Wu Y; Kulharia M; Thutewohl M; Veligodsky A; Kalinin A; Evstifeev V; Ciobanu D; Szedlacsek SE; Waldmann H; Goody RS; Alexandrov K
    J Am Chem Soc; 2006 Mar; 128(9):2822-35. PubMed ID: 16506760
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A protein fluorescence amplifier: continuous fluorometric assay for rab geranylgeranyltransferase.
    Wu YW; Waldmann H; Reents R; Ebetino FH; Goody RS; Alexandrov K
    Chembiochem; 2006 Dec; 7(12):1859-61. PubMed ID: 17086561
    [No Abstract]   [Full Text] [Related]  

  • 4. Design, synthesis, and characterization of peptide-based rab geranylgeranyl transferase inhibitors.
    Tan KT; Guiu-Rozas E; Bon RS; Guo Z; Delon C; Wetzel S; Arndt S; Alexandrov K; Waldmann H; Goody RS; Wu YW; Blankenfeldt W
    J Med Chem; 2009 Dec; 52(24):8025-37. PubMed ID: 19894725
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphonocarboxylate inhibitors of Rab geranylgeranyl transferase disrupt the prenylation and membrane localization of Rab proteins in osteoclasts in vitro and in vivo.
    Coxon FP; Ebetino FH; Mules EH; Seabra MC; McKenna CE; Rogers MJ
    Bone; 2005 Sep; 37(3):349-58. PubMed ID: 16006204
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro assembly, purification, and crystallization of the rab geranylgeranyl transferase:substrate complex.
    Rak A; Niculae A; Kalinin A; Thomä NH; Sidorovitch V; Goody RS; Alexandrov K
    Protein Expr Purif; 2002 Jun; 25(1):23-30. PubMed ID: 12071695
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of yeast Rab geranylgeranyl transferase with its protein and lipid substrates.
    Dursina B; Thomä NH; Sidorovitch V; Niculae A; Iakovenko A; Rak A; Albert S; Ceacareanu AC; Kölling R; Herrmann C; Goody RS; Alexandrov K
    Biochemistry; 2002 May; 41(21):6805-16. PubMed ID: 12022885
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Analysis of protein prenylation in vitro and in vivo using functionalized phosphoisoprenoids.
    Nguyen UT; Wu Y; Goodall A; Alexandrov K
    Curr Protoc Protein Sci; 2010 Nov; Chapter 14():Unit14.3. PubMed ID: 21104984
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Didehydrofarnesyl diphosphate: an intrinsically fluorescent inhibitor of protein farnesyltransferase.
    Liu XH; Prestwich GD
    Bioorg Med Chem Lett; 2004 May; 14(9):2137-40. PubMed ID: 15080995
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of the ternary complex between Rab7, REP-1 and Rab geranylgeranyl transferase.
    Alexandrov K; Simon I; Yurchenko V; Iakovenko A; Rostkova E; Scheidig AJ; Goody RS
    Eur J Biochem; 1999 Oct; 265(1):160-70. PubMed ID: 10491170
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allosteric regulation of substrate binding and product release in geranylgeranyltransferase type II.
    Thomä NH; Iakovenko A; Kalinin A; Waldmann H; Goody RS; Alexandrov K
    Biochemistry; 2001 Jan; 40(1):268-74. PubMed ID: 11141079
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphoisoprenoids modulate association of Rab geranylgeranyltransferase with REP-1.
    Thomä NH; Iakovenko A; Goody RS; Alexandrov K
    J Biol Chem; 2001 Dec; 276(52):48637-43. PubMed ID: 11675392
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphoisoprenoid binding specificity of geranylgeranyltransferase type II.
    Thomä NH; Iakovenko A; Owen D; Scheidig AS; Waldmann H; Goody RS; Alexandrov K
    Biochemistry; 2000 Oct; 39(39):12043-52. PubMed ID: 11009619
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Double prenylation by RabGGTase can proceed without dissociation of the mono-prenylated intermediate.
    Thomä NH; Niculae A; Goody RS; Alexandrov K
    J Biol Chem; 2001 Dec; 276(52):48631-6. PubMed ID: 11591706
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and application of a fluorescent substrate analogue to study ligand interactions for undecaprenyl pyrophosphate synthase.
    Chen AP; Chen YH; Liu HP; Li YC; Chen CT; Liang PH
    J Am Chem Soc; 2002 Dec; 124(51):15217-24. PubMed ID: 12487597
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase.
    Deraeve C; Guo Z; Bon RS; Blankenfeldt W; DiLucrezia R; Wolf A; Menninger S; Stigter EA; Wetzel S; Choidas A; Alexandrov K; Waldmann H; Goody RS; Wu YW
    J Am Chem Soc; 2012 May; 134(17):7384-91. PubMed ID: 22480322
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of selective, potent RabGGTase inhibitors.
    Stigter EA; Guo Z; Bon RS; Wu YW; Choidas A; Wolf A; Menninger S; Waldmann H; Blankenfeldt W; Goody RS
    J Med Chem; 2012 Oct; 55(19):8330-40. PubMed ID: 22963166
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel irreversible fluorescent probes targeting the 18 kDa translocator protein: synthesis and biological characterization.
    Taliani S; Da Pozzo E; Bellandi M; Bendinelli S; Pugliesi I; Simorini F; La Motta C; Salerno S; Marini AM; Da Settimo F; Cosimelli B; Greco G; Novellino E; Martini C
    J Med Chem; 2010 May; 53(10):4085-93. PubMed ID: 20438080
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intein-mediated construction of a library of fluorescent Rab GTPase probes.
    Wu YW; Goody RS; Alexandrov K
    Chembiochem; 2011 Dec; 12(18):2813-21. PubMed ID: 22086656
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis of fluorescently tagged isoprenoid bisphosphonates that inhibit protein geranylgeranylation.
    Maalouf MA; Wiemer AJ; Kuder CH; Hohl RJ; Wiemer DF
    Bioorg Med Chem; 2007 Mar; 15(5):1959-66. PubMed ID: 17254791
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.