These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 1801747)

  • 1. Probing the distance between the two binding sites of hirudin for its interaction with the active site and the fibrin(ogen)-binding site of alpha-thrombin.
    Wagner U; Schmitz T; Otte M; Dodt J
    Biomed Biochim Acta; 1991; 50(4-6):707-10. PubMed ID: 1801747
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationships of recombinant hirudins.
    Stürzebecher J; Walsmann P
    Semin Thromb Hemost; 1991 Apr; 17(2):94-8. PubMed ID: 1771418
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of site specific amino acid exchanges in hirudin on the thrombin-hirudin interaction.
    Köhler S; Dodt J
    Folia Haematol Int Mag Klin Morphol Blutforsch; 1988; 115(1-2):24-9. PubMed ID: 2459027
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thrombin inhibition by hirudin: how hirudin inhibits thrombin.
    Fenton JW; Villanueva GB; Ofosu FA; Maraganore JM
    Haemostasis; 1991; 21 Suppl 1():27-31. PubMed ID: 1894193
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interaction of site specific hirudin variants with alpha-thrombin.
    Dodt J; Köhler S; Baici A
    FEBS Lett; 1988 Feb; 229(1):87-90. PubMed ID: 3345842
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanism of the inhibition of alpha-thrombin by hirudin-derived fragments hirudin(1-47) and hirudin(45-65).
    Schmitz T; Rothe M; Dodt J
    Eur J Biochem; 1991 Jan; 195(1):251-6. PubMed ID: 1991472
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular dynamics simulations of thrombin inhibitors at the S' subsites of thrombin.
    Yue SY; Konishi Y
    Drug Des Discov; 1994 Jul; 12(1):1-17. PubMed ID: 7578804
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Binding of fibrin monomer and heparin to thrombin in a ternary complex alters the environment of the thrombin catalytic site, reduces affinity for hirudin, and inhibits cleavage of fibrinogen.
    Hogg PJ; Jackson CM; Labanowski JK; Bock PE
    J Biol Chem; 1996 Oct; 271(42):26088-95. PubMed ID: 8824251
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitory mechanism of serpins. Identification of steps involving the active-site serine residue of the protease.
    Stone SR; Le Bonniec BF
    J Mol Biol; 1997 Jan; 265(3):344-62. PubMed ID: 9018048
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-function and refolding studies of the thrombin-specific inhibitor hirudin.
    Johnson PH; Sze P; Winant RC; Hudson D; Underhill P; Lazar JB; Olsen C; Almquist R
    Haemostasis; 1991; 21 Suppl 1():41-8. PubMed ID: 1894196
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allosteric changes of thrombin catalytic site induced by interaction of bothrojaracin with anion-binding exosites I and II.
    Monteiro RQ; Rapôso JG; Wisner A; Guimarães JA; Bon C; Zingali RB
    Biochem Biophys Res Commun; 1999 Sep; 262(3):819-22. PubMed ID: 10471408
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recombinant hirudin: genetic engineering and structure analysis.
    Märki WE; Grossenbacher H; Grütter MG; Liersch MH; Meyhack B; Heim J
    Semin Thromb Hemost; 1991 Apr; 17(2):88-93. PubMed ID: 1771417
    [No Abstract]   [Full Text] [Related]  

  • 13. Interaction of hirudin with the dysthrombins Quick I and II.
    Stone SR; Schmitz T; Henriksen RA; Hofsteenge J; Dodt J
    Biochemistry; 1991 Jul; 30(26):6392-7. PubMed ID: 2054344
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bothrojaracin: a potent two-site-directed thrombin inhibitor.
    Arocas V; Zingali RB; Guillin MC; Bon C; Jandrot-Perrus M
    Biochemistry; 1996 Jul; 35(28):9083-9. PubMed ID: 8703912
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of MDL 28,050, a small stable antithrombin agent based on a functional domain of the leech protein, hirudin.
    Krstenansky JL; Broersma RJ; Owen TJ; Payne MH; Yates MT; Mao SJ
    Thromb Haemost; 1990 Apr; 63(2):208-14. PubMed ID: 2363122
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thrombin interactions with hirudin.
    Fenton JW
    Semin Thromb Hemost; 1989 Jul; 15(3):265-8. PubMed ID: 2688098
    [No Abstract]   [Full Text] [Related]  

  • 17. The COOH-terminal domain of hirudin. An exosite-directed competitive inhibitor of the action of alpha-thrombin on fibrinogen.
    Naski MC; Fenton JW; Maraganore JM; Olson ST; Shafer JA
    J Biol Chem; 1990 Aug; 265(23):13484-9. PubMed ID: 2380171
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deciphering the structural elements of hirudin C-terminal peptide that bind to the fibrinogen recognition site of alpha-thrombin.
    Chang JY
    Biochemistry; 1991 Jul; 30(27):6656-61. PubMed ID: 2065053
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Affects of hirudin and heparin on the binding of new fibrin to the thrombus in t-PA treated rabbits.
    Agnelli G; Pascucci C; Cosmi B; Nenci GG
    Thromb Haemost; 1991 Nov; 66(5):592-7. PubMed ID: 1839474
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-function relationships of the C-terminal functional domain of hirudin and its variants.
    Krstenansky JL; Mao SJ
    Blood Coagul Fibrinolysis; 1991 Feb; 2(1):91-6. PubMed ID: 1773003
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.