These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

595 related articles for article (PubMed ID: 18022370)

  • 1. LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase.
    Reczek D; Schwake M; Schröder J; Hughes H; Blanz J; Jin X; Brondyk W; Van Patten S; Edmunds T; Saftig P
    Cell; 2007 Nov; 131(4):770-83. PubMed ID: 18022370
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand beta-glucocerebrosidase.
    Blanz J; Groth J; Zachos C; Wehling C; Saftig P; Schwake M
    Hum Mol Genet; 2010 Feb; 19(4):563-72. PubMed ID: 19933215
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mannose 6-phosphate-independent Lysosomal Sorting of LIMP-2.
    Blanz J; Zunke F; Markmann S; Damme M; Braulke T; Saftig P; Schwake M
    Traffic; 2015 Oct; 16(10):1127-36. PubMed ID: 26219725
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lysosomal integral membrane protein 2 (LIMP-2) restricts the invasion of Trypanosoma cruzi extracellular amastigotes through the activity of the lysosomal enzyme β-glucocerebrosidase.
    Gonçalves VM; D'Almeida V; Müller KB; Real F; Mortara RA
    Microbes Infect; 2014 Mar; 16(3):253-60. PubMed ID: 24269705
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lysosomal integral membrane protein type-2 (LIMP-2/SCARB2) is a substrate of cathepsin-F, a cysteine protease mutated in type-B-Kufs-disease.
    Peters J; Rittger A; Weisner R; Knabbe J; Zunke F; Rothaug M; Damme M; Berkovic SF; Blanz J; Saftig P; Schwake M
    Biochem Biophys Res Commun; 2015 Feb; 457(3):334-40. PubMed ID: 25576872
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A critical histidine residue within LIMP-2 mediates pH sensitive binding to its ligand β-glucocerebrosidase.
    Zachos C; Blanz J; Saftig P; Schwake M
    Traffic; 2012 Aug; 13(8):1113-23. PubMed ID: 22537104
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Intracellular transport of acid beta-glucosidase and lysosome-associated membrane proteins is affected in Gaucher's disease (G202R mutation).
    Zimmer KP; le Coutre P; Aerts HM; Harzer K; Fukuda M; O'Brien JS; Naim HY
    J Pathol; 1999 Aug; 188(4):407-14. PubMed ID: 10440752
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A shortcut to the lysosome: the mannose-6-phosphate-independent pathway.
    Coutinho MF; Prata MJ; Alves S
    Mol Genet Metab; 2012 Nov; 107(3):257-66. PubMed ID: 22884962
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impaired trafficking of mutants of lysosomal glucocerebrosidase in Gaucher's disease.
    Schmitz M; Alfalah M; Aerts JM; Naim HY; Zimmer KP
    Int J Biochem Cell Biol; 2005 Nov; 37(11):2310-20. PubMed ID: 15982918
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lysosome sorting of β-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor.
    Zhao Y; Ren J; Padilla-Parra S; Fry EE; Stuart DI
    Nat Commun; 2014 Jul; 5():4321. PubMed ID: 25027712
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice.
    Gamp AC; Tanaka Y; Lüllmann-Rauch R; Wittke D; D'Hooge R; De Deyn PP; Moser T; Maier H; Hartmann D; Reiss K; Illert AL; von Figura K; Saftig P
    Hum Mol Genet; 2003 Mar; 12(6):631-46. PubMed ID: 12620969
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lysosomal membrane proteins: life between acid and neutral conditions.
    Saftig P; Schröder B; Blanz J
    Biochem Soc Trans; 2010 Dec; 38(6):1420-3. PubMed ID: 21118100
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy.
    Schroen B; Leenders JJ; van Erk A; Bertrand AT; van Loon M; van Leeuwen RE; Kubben N; Duisters RF; Schellings MW; Janssen BJ; Debets JJ; Schwake M; Høydal MA; Heymans S; Saftig P; Pinto YM
    J Exp Med; 2007 May; 204(5):1227-35. PubMed ID: 17485520
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hydrophilic iminosugar active-site-specific chaperones increase residual glucocerebrosidase activity in fibroblasts from Gaucher patients.
    Chang HH; Asano N; Ishii S; Ichikawa Y; Fan JQ
    FEBS J; 2006 Sep; 273(17):4082-92. PubMed ID: 16934036
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lysosomal integral membrane protein-2: a new player in lysosome-related pathology.
    Gonzalez A; Valeiras M; Sidransky E; Tayebi N
    Mol Genet Metab; 2014 Feb; 111(2):84-91. PubMed ID: 24389070
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gaucher disease: forging a new path to the lysosome.
    Griffiths GM
    Cell; 2007 Nov; 131(4):647-9. PubMed ID: 18022357
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A nonsense mutation in the LIMP-2 gene associated with progressive myoclonic epilepsy and nephrotic syndrome.
    Balreira A; Gaspar P; Caiola D; Chaves J; Beirão I; Lima JL; Azevedo JE; Miranda MC
    Hum Mol Genet; 2008 Jul; 17(14):2238-43. PubMed ID: 18424452
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Localization of active endogenous and exogenous β-glucocerebrosidase by correlative light-electron microscopy in human fibroblasts.
    van Meel E; Bos E; van der Lienden MJC; Overkleeft HS; van Kasteren SI; Koster AJ; Aerts JMFG
    Traffic; 2019 May; 20(5):346-356. PubMed ID: 30895685
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The LIMP-2/SCARB2 binding motif on acid β-glucosidase: basic and applied implications for Gaucher disease and associated neurodegenerative diseases.
    Liou B; Haffey WD; Greis KD; Grabowski GA
    J Biol Chem; 2014 Oct; 289(43):30063-74. PubMed ID: 25202012
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of the complex formed by β-glucocerebrosidase and the lysosomal integral membrane protein type-2.
    Zunke F; Andresen L; Wesseler S; Groth J; Arnold P; Rothaug M; Mazzulli JR; Krainc D; Blanz J; Saftig P; Schwake M
    Proc Natl Acad Sci U S A; 2016 Apr; 113(14):3791-6. PubMed ID: 27001828
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.