BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 18023181)

  • 1. Trisubstituted 1,2,4-triazoles as ligands for the ghrelin receptor: on the significance of the orientation and substitution at position 3.
    Moulin A; Demange L; Ryan J; M'Kadmi C; Galleyrand JC; Martinez J; Fehrentz JA
    Bioorg Med Chem Lett; 2008 Jan; 18(1):164-8. PubMed ID: 18023181
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Toward potent ghrelin receptor ligands based on trisubstituted 1,2,4-triazole structure. 2. Synthesis and pharmacological in vitro and in vivo evaluations.
    Moulin A; Demange L; Bergé G; Gagne D; Ryan J; Mousseaux D; Heitz A; Perrissoud D; Locatelli V; Torsello A; Galleyrand JC; Fehrentz JA; Martinez J
    J Med Chem; 2007 Nov; 50(23):5790-806. PubMed ID: 17927165
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New trisubstituted 1,2,4-triazoles as ghrelin receptor antagonists.
    Blayo AL; Maingot M; Aicher B; M'Kadmi C; Schmidt P; Müller G; Teifel M; Günther E; Gagne D; Denoyelle S; Martinez J; Fehrentz JA
    Bioorg Med Chem Lett; 2015 Jan; 25(1):20-4. PubMed ID: 25435152
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New trisubstituted 1,2,4-triazole derivatives as potent ghrelin receptor antagonists. 3. Synthesis and pharmacological in vitro and in vivo evaluations.
    Moulin A; Demange L; Ryan J; Mousseaux D; Sanchez P; Bergé G; Gagne D; Perrissoud D; Locatelli V; Torsello A; Galleyrand JC; Fehrentz JA; Martinez J
    J Med Chem; 2008 Feb; 51(3):689-93. PubMed ID: 18193826
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959, a potent antagonist.
    Moulin A; Brunel L; Boeglin D; Demange L; Ryan J; M'Kadmi C; Denoyelle S; Martinez J; Fehrentz JA
    Amino Acids; 2013 Feb; 44(2):301-14. PubMed ID: 22798076
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modulation of the constitutive activity of the ghrelin receptor by use of pharmacological tools and mutagenesis.
    Mokrosiński J; Holst B
    Methods Enzymol; 2010; 484():53-73. PubMed ID: 21036226
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and pharmacological in vitro and in vivo evaluations of novel triazole derivatives as ligands of the ghrelin receptor. 1.
    Demange L; Boeglin D; Moulin A; Mousseaux D; Ryan J; Bergé G; Gagne D; Heitz A; Perrissoud D; Locatelli V; Torsello A; Galleyrand JC; Fehrentz JA; Martinez J
    J Med Chem; 2007 Apr; 50(8):1939-57. PubMed ID: 17375904
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recent developments in ghrelin receptor ligands.
    Moulin A; Ryan J; Martinez J; Fehrentz JA
    ChemMedChem; 2007 Sep; 2(9):1242-59. PubMed ID: 17520591
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ghrelin receptor modulators and their therapeutic potential.
    Costantino L; Barlocco D
    Future Med Chem; 2009 Apr; 1(1):157-77. PubMed ID: 21426074
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New ligands of the ghrelin receptor based on the 1,2,4-triazole scaffold by introduction of a second chiral center.
    Maingot M; Blayo AL; Denoyelle S; M'Kadmi C; Damian M; Mary S; Gagne D; Sanchez P; Aicher B; Schmidt P; Müller G; Teifel M; Günther E; Marie J; Banères JL; Martinez J; Fehrentz JA
    Bioorg Med Chem Lett; 2016 May; 26(10):2408-2412. PubMed ID: 27072910
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel triazole derivatives with improved receptor activity and bioavailability properties as ghrelin antagonists of growth hormone secretagogue receptors (WO2012035124): a patent evaluation.
    Costantino L
    Expert Opin Ther Pat; 2012 Sep; 22(9):1099-104. PubMed ID: 22809244
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ghrelin--a novel generation of anti-obesity drug: design, pharmacomodulation and biological activity of ghrelin analogues.
    Chollet C; Meyer K; Beck-Sickinger AG
    J Pept Sci; 2009 Nov; 15(11):711-30. PubMed ID: 19787814
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aryl sulphonyl amides as potent agonists of the growth hormone secretagogue (ghrelin) receptor.
    Witherington J; Abberley L; Bellenie BR; Boatman R; Collis K; Dean DK; Gaiba A; King NP; Shuker N; Steadman JG; Takle AK; Sanger G; Butler S; McKay F; Muir A; Winborn K; Ward RW; Heightman TD
    Bioorg Med Chem Lett; 2009 Feb; 19(3):684-7. PubMed ID: 19128969
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Motilin, ghrelin and related neuropeptides as targets for the treatment of GI diseases.
    Sanger GJ
    Drug Discov Today; 2008 Mar; 13(5-6):234-9. PubMed ID: 18342799
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potent achiral agonists of the growth hormone secretagogue (ghrelin) receptor. Part 2: Lead optimisation.
    Witherington J; Abberley L; Briggs MA; Collis K; Dean DK; Gaiba A; King NP; Kraus H; Shuker N; Steadman JG; Takle AK; Sanger G; Wadsworth G; Butler S; McKay F; Muir A; Winborn K; Heightman TD
    Bioorg Med Chem Lett; 2008 Mar; 18(6):2203-5. PubMed ID: 18316188
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Anorexigenic and electrophysiological actions of novel ghrelin receptor (GHS-R1A) antagonists in rats.
    Salomé N; Haage D; Perrissoud D; Moulin A; Demange L; Egecioglu E; Fehrentz JA; Martinez J; Dickson SL
    Eur J Pharmacol; 2009 Jun; 612(1-3):167-73. PubMed ID: 19356720
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The constitutive activity of the ghrelin receptor attenuates apoptosis via a protein kinase C-dependent pathway.
    Lau PN; Chow KB; Chan CB; Cheng CH; Wise H
    Mol Cell Endocrinol; 2009 Feb; 299(2):232-9. PubMed ID: 19135127
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 1,4- and 2,4-substituted-1,2,3-triazoles as potential potassium channel activators. VII.
    Calderone V; Giorgi I; Livi O; Martinotti E; Martelli A; Nardi A
    Farmaco; 2005 May; 60(5):367-75. PubMed ID: 15910810
    [TBL] [Abstract][Full Text] [Related]  

  • 19. C-terminus of a hexapeptidic ghrelin receptor inverse agonist can switch peptide behavior from inverse agonism to agonism.
    Els-Heindl S; Bellmann-Sickert K; Beck-Sickinger AG
    Biopolymers; 2016 Jan; 106(1):101-8. PubMed ID: 26566778
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological activity of novel peptide mimetics as melanocortin receptor agonists.
    Liu XW; Ma J; Colson AO; Doersen DC; Ebetino FH
    Bioorg Med Chem Lett; 2008 Feb; 18(3):1223-8. PubMed ID: 18078748
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.