These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

311 related articles for article (PubMed ID: 18023187)

  • 1. Synthesis and cyclooxygenase inhibitory activities of linear 1-(methanesulfonylphenyl or benzenesulfonamido)-2-(pyridyl)acetylene regioisomers.
    Chowdhury MA; Dong Y; Chen QH; Abdellatif KR; Knaus EE
    Bioorg Med Chem; 2008 Feb; 16(4):1948-56. PubMed ID: 18023187
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and biological evaluation of linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: a novel class of cyclooxygenase-2 inhibitors.
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2005 Dec; 13(23):6425-34. PubMed ID: 16099663
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of linear phenylethynylbenzenesulfonamide regioisomers as cyclooxygenase-1/-2 (COX-1/-2) inhibitors.
    Anana R; Rao PN; Chen QH; Knaus EE
    Bioorg Med Chem; 2006 Aug; 14(15):5259-65. PubMed ID: 16635574
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases.
    Moreau A; Chen QH; Praveen Rao PN; Knaus EE
    Bioorg Med Chem; 2006 Dec; 14(23):7716-27. PubMed ID: 16931030
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN; Chen QH; Knaus EE
    J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of 1-(methanesulfonyl- and aminosulfonylphenyl)acetylenes that possess a 2-(N-difluoromethyl-1,2-dihydropyridin-2-one) pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Rahman M; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2009 Feb; 19(3):584-8. PubMed ID: 19136259
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.
    Praveen Rao PN; Amini M; Li H; Habeeb AG; Knaus EE
    J Med Chem; 2003 Nov; 46(23):4872-82. PubMed ID: 14584938
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors.
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2005 Aug; 13(15):4694-703. PubMed ID: 15914011
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and structure-activity relationship studies of 3,4,6-triphenylpyran-2-ones as selective cyclooxygenase-2 inhibitors.
    Rao PN; Uddin MJ; Knaus EE
    J Med Chem; 2004 Jul; 47(16):3972-90. PubMed ID: 15267236
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of acyclic triaryl (Z)-olefins possessing a 3,5-di-tert-butyl-4-hydroxyphenyl pharmacophore: dual inhibitors of cyclooxygenases and lipoxygenases.
    Moreau A; Rao PN; Knaus EE
    Bioorg Med Chem; 2006 Aug; 14(15):5340-50. PubMed ID: 16677817
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of 1,3-diarylprop-2-en-1-ones : a novel class of cyclooxygenase-2 inhibitors.
    Zarghi A; Arfaee S; Rao PN; Knaus EE
    Bioorg Med Chem; 2006 Apr; 14(8):2600-5. PubMed ID: 16356730
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2006 Dec; 14(23):7898-909. PubMed ID: 16904331
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of 1,3-diarylurea derivatives as selective cyclooxygenase (COX-2) inhibitors.
    Zarghi A; Kakhgi S; Hadipoor A; Daraee B; Dadrass OG; Hedayati M
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1336-9. PubMed ID: 18226898
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential hybrid COX-2 inhibitor/nitric oxide donor agents.
    Velázquez C; Rao PN; McDonald R; Knaus EE
    Bioorg Med Chem; 2005 Apr; 13(8):2749-57. PubMed ID: 15781386
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of new rofecoxib analogs as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of the methanesulfonyl pharmacophore by a N-acetylsulfonamido bioisostere.
    Zarghi A; Rao PN; Knaus EE
    J Pharm Pharm Sci; 2007; 10(2):159-67. PubMed ID: 17706175
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6138-41. PubMed ID: 18945614
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of methanesulfonamide analogues of rofecoxib: Replacement of methanesulfonyl by methanesulfonamido decreases cyclooxygenase-2 selectivity.
    Zarghi A; Praveen Rao PN; Knaus EE
    Bioorg Med Chem; 2007 Jan; 15(2):1056-61. PubMed ID: 17067801
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Covalent modification of cyclooxygenase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators.
    Kalgutkar AS; Kozak KR; Crews BC; Hochgesang GP; Marnett LJ
    J Med Chem; 1998 Nov; 41(24):4800-18. PubMed ID: 9822550
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives.
    Wuest F; Tang X; Kniess T; Pietzsch J; Suresh M
    Bioorg Med Chem; 2009 Feb; 17(3):1146-51. PubMed ID: 19157881
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of 3-alkyl-2-aryl-1,3-thiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors.
    Zebardast T; Zarghi A; Daraie B; Hedayati M; Dadrass OG
    Bioorg Med Chem Lett; 2009 Jun; 19(12):3162-5. PubMed ID: 19447036
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.