BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 18025151)

  • 21. Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3.
    Nielsen M; Nissen MH; Gerwien J; Zocca MB; Rasmussen HM; Nakajima K; Röpke C; Geisler C; Kaltoft K; Ødum N
    Blood; 2002 Feb; 99(3):973-7. PubMed ID: 11807001
    [TBL] [Abstract][Full Text] [Related]  

  • 22. CD4 T-cell cytokines synergize to induce proliferation of malignant and nonmalignant innate intraepithelial lymphocytes.
    Kooy-Winkelaar YM; Bouwer D; Janssen GM; Thompson A; Brugman MH; Schmitz F; de Ru AH; van Gils T; Bouma G; van Rood JJ; van Veelen PA; Mearin ML; Mulder CJ; Koning F; van Bergen J
    Proc Natl Acad Sci U S A; 2017 Feb; 114(6):E980-E989. PubMed ID: 28049849
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival.
    Wang Y; Mikhailova M; Bose S; Pan CX; deVere White RW; Ghosh PM
    Oncogene; 2008 Nov; 27(56):7106-17. PubMed ID: 18776922
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Activation of mTORC1 signaling pathway in AIDS-related lymphomas.
    El-Salem M; Raghunath PN; Marzec M; Liu X; Kasprzycka M; Robertson E; Wasik MA
    Am J Pathol; 2009 Aug; 175(2):817-24. PubMed ID: 19608873
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells.
    Varin J; Poulain L; Hivelin M; Nusbaum P; Hubas A; Laurendeau I; Lantieri L; Wolkenstein P; Vidaud M; Pasmant E; Chapuis N; Parfait B
    Oncotarget; 2016 Jun; 7(24):35753-35767. PubMed ID: 26840085
    [TBL] [Abstract][Full Text] [Related]  

  • 26. PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORγ.
    Kurebayashi Y; Nagai S; Ikejiri A; Ohtani M; Ichiyama K; Baba Y; Yamada T; Egami S; Hoshii T; Hirao A; Matsuda S; Koyasu S
    Cell Rep; 2012 Apr; 1(4):360-73. PubMed ID: 22832227
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells.
    Holler M; Grottke A; Mueck K; Manes J; Jücker M; Rodemann HP; Toulany M
    PLoS One; 2016; 11(5):e0154745. PubMed ID: 27137757
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Rapamycin regulates Akt and ERK phosphorylation through mTORC1 and mTORC2 signaling pathways.
    Chen XG; Liu F; Song XF; Wang ZH; Dong ZQ; Hu ZQ; Lan RZ; Guan W; Zhou TG; Xu XM; Lei H; Ye ZQ; Peng EJ; Du LH; Zhuang QY
    Mol Carcinog; 2010 Jun; 49(6):603-10. PubMed ID: 20512842
    [TBL] [Abstract][Full Text] [Related]  

  • 29. CBAP modulates Akt-dependent TSC2 phosphorylation to promote Rheb-mTORC1 signaling and growth of T-cell acute lymphoblastic leukemia.
    Chiang YJ; Liao WT; Ho KC; Wang SH; Chen YG; Ho CL; Huang SF; Shih LY; Yang-Yen HF; Yen JJ
    Oncogene; 2019 Feb; 38(9):1432-1447. PubMed ID: 30266989
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells.
    Lasithiotakis KG; Sinnberg TW; Schittek B; Flaherty KT; Kulms D; Maczey E; Garbe C; Meier FE
    J Invest Dermatol; 2008 Aug; 128(8):2013-23. PubMed ID: 18323781
    [TBL] [Abstract][Full Text] [Related]  

  • 31. mTORC1-S6K activation by endotoxin contributes to cytokine up-regulation and early lethality in animals.
    Lee PS; Wilhelmson AS; Hubner AP; Reynolds SB; Gallacchi DA; Chiou TT; Kwiatkowski DJ
    PLoS One; 2010 Dec; 5(12):e14399. PubMed ID: 21200439
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cutaneous T cell lymphoma expresses immunosuppressive CD80 (B7-1) cell surface protein in a STAT5-dependent manner.
    Zhang Q; Wang HY; Wei F; Liu X; Paterson JC; Roy D; Mihova D; Woetmann A; Ptasznik A; Odum N; Schuster SJ; Marafioti T; Riley JL; Wasik MA
    J Immunol; 2014 Mar; 192(6):2913-9. PubMed ID: 24523507
    [TBL] [Abstract][Full Text] [Related]  

  • 33. CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo.
    Dormond O; Contreras AG; Meijer E; Datta D; Flynn E; Pal S; Briscoe DM
    J Immunol; 2008 Dec; 181(11):8088-95. PubMed ID: 19018001
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Cutaneous T cell lymphoma: the helping hand of dendritic cells.
    Edelson RL
    Ann N Y Acad Sci; 2001 Sep; 941():1-11. PubMed ID: 11594563
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Expansion of CD4(+)CD25 (+) regulatory T cells from cord blood CD4(+) cells using the common γ-chain cytokines (IL-2 and IL-15) and rapamycin.
    Asanuma S; Tanaka J; Sugita J; Kosugi M; Shiratori S; Wakasa K; Shono Y; Shigematsu A; Kondo T; Kobayashi T; Asaka M; Imamura M
    Ann Hematol; 2011 Jun; 90(6):617-24. PubMed ID: 21107839
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome.
    Zhang Q; Nowak I; Vonderheid EC; Rook AH; Kadin ME; Nowell PC; Shaw LM; Wasik MA
    Proc Natl Acad Sci U S A; 1996 Aug; 93(17):9148-53. PubMed ID: 8799169
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction.
    Ito M; Yurube T; Kakutani K; Maeno K; Takada T; Terashima Y; Kakiuchi Y; Takeoka Y; Miyazaki S; Kuroda R; Nishida K
    Osteoarthritis Cartilage; 2017 Dec; 25(12):2134-2146. PubMed ID: 28888905
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways.
    Tamburini J; Chapuis N; Bardet V; Park S; Sujobert P; Willems L; Ifrah N; Dreyfus F; Mayeux P; Lacombe C; Bouscary D
    Blood; 2008 Jan; 111(1):379-82. PubMed ID: 17878402
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dual inhibition of the mTORC1 and mTORC2 signaling pathways is a promising therapeutic target for adult T-cell leukemia.
    Kawata T; Tada K; Kobayashi M; Sakamoto T; Takiuchi Y; Iwai F; Sakurada M; Hishizawa M; Shirakawa K; Shindo K; Sato H; Takaori-Kondo A
    Cancer Sci; 2018 Jan; 109(1):103-111. PubMed ID: 29077243
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta.
    Rahimi RA; Andrianifahanana M; Wilkes MC; Edens M; Kottom TJ; Blenis J; Leof EB
    Cancer Res; 2009 Jan; 69(1):84-93. PubMed ID: 19117990
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.