BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

325 related articles for article (PubMed ID: 18027090)

  • 1. Syndecan-1: a dynamic regulator of the myeloma microenvironment.
    Sanderson RD; Yang Y
    Clin Exp Metastasis; 2008; 25(2):149-59. PubMed ID: 18027090
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heparan sulfate proteoglycans and heparanase--partners in osteolytic tumor growth and metastasis.
    Sanderson RD; Yang Y; Suva LJ; Kelly T
    Matrix Biol; 2004 Oct; 23(6):341-52. PubMed ID: 15533755
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy.
    Yang Y; MacLeod V; Dai Y; Khotskaya-Sample Y; Shriver Z; Venkataraman G; Sasisekharan R; Naggi A; Torri G; Casu B; Vlodavsky I; Suva LJ; Epstein J; Yaccoby S; Shaughnessy JD; Barlogie B; Sanderson RD
    Blood; 2007 Sep; 110(6):2041-8. PubMed ID: 17536013
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Syndecan-1 and stromal heparan sulfate proteoglycans: key moderators of plasma cell biology and myeloma pathogenesis.
    Ren Z; Spaargaren M; Pals ST
    Blood; 2021 Apr; 137(13):1713-1718. PubMed ID: 33512430
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heparanase degrades syndecan-1 and perlecan heparan sulfate: functional implications for tumor cell invasion.
    Reiland J; Sanderson RD; Waguespack M; Barker SA; Long R; Carson DD; Marchetti D
    J Biol Chem; 2004 Feb; 279(9):8047-55. PubMed ID: 14630925
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis.
    Purushothaman A; Uyama T; Kobayashi F; Yamada S; Sugahara K; Rapraeger AC; Sanderson RD
    Blood; 2010 Mar; 115(12):2449-57. PubMed ID: 20097882
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Heparanase-1-induced shedding of heparan sulfate from syndecan-1 in hepatocarcinoma cell facilitates lymphatic endothelial cell proliferation via VEGF-C/ERK pathway.
    Yu S; Lv H; Zhang H; Jiang Y; Hong Y; Xia R; Zhang Q; Ju W; Jiang L; Ou G; Zhang J; Wang S; Zhang J
    Biochem Biophys Res Commun; 2017 Apr; 485(2):432-439. PubMed ID: 28209511
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.
    Dai Y; Yang Y; MacLeod V; Yue X; Rapraeger AC; Shriver Z; Venkataraman G; Sasisekharan R; Sanderson RD
    J Biol Chem; 2005 Dec; 280(48):40066-73. PubMed ID: 16192265
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis.
    Yang Y; Macleod V; Miao HQ; Theus A; Zhan F; Shaughnessy JD; Sawyer J; Li JP; Zcharia E; Vlodavsky I; Sanderson RD
    J Biol Chem; 2007 May; 282(18):13326-33. PubMed ID: 17347152
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Syndecan-1 promotes Wnt/β-catenin signaling in multiple myeloma by presenting Wnts and R-spondins.
    Ren Z; van Andel H; de Lau W; Hartholt RB; Maurice MM; Clevers H; Kersten MJ; Spaargaren M; Pals ST
    Blood; 2018 Mar; 131(9):982-994. PubMed ID: 29212806
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heparanase stimulation of protease expression implicates it as a master regulator of the aggressive tumor phenotype in myeloma.
    Purushothaman A; Chen L; Yang Y; Sanderson RD
    J Biol Chem; 2008 Nov; 283(47):32628-36. PubMed ID: 18812315
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting EXT1 reveals a crucial role for heparan sulfate in the growth of multiple myeloma.
    Reijmers RM; Groen RW; Rozemuller H; Kuil A; de Haan-Kramer A; Csikós T; Martens AC; Spaargaren M; Pals ST
    Blood; 2010 Jan; 115(3):601-4. PubMed ID: 19965677
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Membrane-anchored proteoglycans of mouse macrophages: P388D1 cells express a syndecan-4-like heparan sulfate proteoglycan and a distinct chondroitin sulfate form.
    Yeaman C; Rapraeger AC
    J Cell Physiol; 1993 Nov; 157(2):413-25. PubMed ID: 8227171
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Shed syndecan-1 translocates to the nucleus of cells delivering growth factors and inhibiting histone acetylation: a novel mechanism of tumor-host cross-talk.
    Stewart MD; Ramani VC; Sanderson RD
    J Biol Chem; 2015 Jan; 290(2):941-9. PubMed ID: 25404732
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cell surface proteoglycan syndecan-1 mediates hepatocyte growth factor binding and promotes Met signaling in multiple myeloma.
    Derksen PW; Keehnen RM; Evers LM; van Oers MH; Spaargaren M; Pals ST
    Blood; 2002 Feb; 99(4):1405-10. PubMed ID: 11830493
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The heparanase/syndecan-1 axis in cancer: mechanisms and therapies.
    Ramani VC; Purushothaman A; Stewart MD; Thompson CA; Vlodavsky I; Au JL; Sanderson RD
    FEBS J; 2013 May; 280(10):2294-306. PubMed ID: 23374281
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enzymatic remodeling of heparan sulfate proteoglycans within the tumor microenvironment: growth regulation and the prospect of new cancer therapies.
    Sanderson RD; Yang Y; Kelly T; MacLeod V; Dai Y; Theus A
    J Cell Biochem; 2005 Dec; 96(5):897-905. PubMed ID: 16149080
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multiple heparan sulfate chains are required for optimal syndecan-1 function.
    Langford JK; Stanley MJ; Cao D; Sanderson RD
    J Biol Chem; 1998 Nov; 273(45):29965-71. PubMed ID: 9792716
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior.
    Bandari SK; Purushothaman A; Ramani VC; Brinkley GJ; Chandrashekar DS; Varambally S; Mobley JA; Zhang Y; Brown EE; Vlodavsky I; Sanderson RD
    Matrix Biol; 2018 Jan; 65():104-118. PubMed ID: 28888912
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis.
    Ritchie JP; Ramani VC; Ren Y; Naggi A; Torri G; Casu B; Penco S; Pisano C; Carminati P; Tortoreto M; Zunino F; Vlodavsky I; Sanderson RD; Yang Y
    Clin Cancer Res; 2011 Mar; 17(6):1382-93. PubMed ID: 21257720
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.