BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 18029688)

  • 21. Antitumor activity of sequence-specific alkylating agents: pyrolle-imidazole CBI conjugates with indole linker.
    Shinohara K; Bando T; Sasaki S; Sakakibara Y; Minoshima M; Sugiyama H
    Cancer Sci; 2006 Mar; 97(3):219-25. PubMed ID: 16542219
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Sequence-specific gene silencing by alkylating Py-Im polyamide.
    Shinohara K; Sasaki S; Bando T; Sugiyama H
    Nucleic Acids Symp Ser (Oxf); 2005; (49):75-6. PubMed ID: 17150640
    [TBL] [Abstract][Full Text] [Related]  

  • 23. DNA Interstrand Crosslinks by H-pin Polyamide (S)-seco-CBI Conjugates.
    Guo C; Asamitsu S; Kashiwazaki G; Sato S; Bando T; Sugiyama H
    Chembiochem; 2017 Jan; 18(2):166-170. PubMed ID: 27862755
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Molecular design of a pyrrole-imidazole hairpin polyamides for effective DNA alkylation.
    Bando T; Narita A; Saito I; Sugiyama H
    Chemistry; 2002 Oct; 8(20):4781-90. PubMed ID: 12561118
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and biological properties of sequence-specific DNA-alkylating pyrrole-imidazole polyamides.
    Bando T; Sugiyama H
    Acc Chem Res; 2006 Dec; 39(12):935-44. PubMed ID: 17176032
    [TBL] [Abstract][Full Text] [Related]  

  • 26. C-H to N substitution dramatically alters the sequence-specific DNA alkylation, cytotoxicity, and expression of human cancer cell lines.
    Bando T; Narita A; Iwai A; Kihara K; Sugiyama H
    J Am Chem Soc; 2004 Mar; 126(11):3406-7. PubMed ID: 15025451
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Highly efficient sequence-specific DNA interstrand cross-linking by pyrrole/imidazole CPI conjugates.
    Bando T; Narita A; Saito I; Sugiyama H
    J Am Chem Soc; 2003 Mar; 125(12):3471-85. PubMed ID: 12643709
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Sequence-specific DNA alkylation by tandem Py-Im polyamide conjugates.
    Taylor RD; Kawamoto Y; Hashiya K; Bando T; Sugiyama H
    Chem Asian J; 2014 Sep; 9(9):2527-33. PubMed ID: 24942204
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Potent activity against K562 cells by polyamide-seco-CBI conjugates targeting histone H4 genes.
    Minoshima M; Chou JC; Lefebvre S; Bando T; Shinohara K; Gottesfeld JM; Sugiyama H
    Bioorg Med Chem; 2010 Jan; 18(1):168-74. PubMed ID: 19962902
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Sequence-specific DNA alkylation targeting for Kras codon 13 mutation by pyrrole-imidazole polyamide seco-CBI conjugates.
    Taylor RD; Asamitsu S; Takenaka T; Yamamoto M; Hashiya K; Kawamoto Y; Bando T; Nagase H; Sugiyama H
    Chemistry; 2014 Jan; 20(5):1310-7. PubMed ID: 24382626
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Molecular design of hairpin pyrrole-imidazole polyamides possessing sequence specific DNA alkylating moiety.
    Narita A; Bando T; Sugiyama H
    Nucleic Acids Res Suppl; 2003; (3):119-20. PubMed ID: 14510409
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Sequence-specific gene silencing in mammalian cells by alkylating pyrrole-imidazole polyamides.
    Shinohara K; Narita A; Oyoshi T; Bando T; Teraoka H; Sugiyama H
    J Am Chem Soc; 2004 Apr; 126(16):5113-8. PubMed ID: 15099094
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis and biological properties of highly sequence-specific-alkylating N-methylpyrrole-N-methylimidazole polyamide conjugates.
    Kashiwazaki G; Bando T; Yoshidome T; Masui S; Takagaki T; Hashiya K; Pandian GN; Yasuoka J; Akiyoshi K; Sugiyama H
    J Med Chem; 2012 Mar; 55(5):2057-66. PubMed ID: 22309169
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design and synthesis of bis 1-chloromethyl-5-hydroxy-1,2- dihydro-3H-benz[e]indole (seco-CBI)-pyrrole polyamide conjugates.
    Kumar R; Lown JW
    Org Lett; 2002 May; 4(11):1851-4. PubMed ID: 12027630
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Anticancer activities of alkylating pyrrole-imidazole polyamides with specific sequence recognition.
    Shinohara K; Bando T; Sugiyama H
    Anticancer Drugs; 2010 Mar; 21(3):228-42. PubMed ID: 20038830
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Evaluation of PI polyamide conjugates with eight-base pair recognition and improvement of the aqueous solubility by PEGylation.
    Takagaki T; Bando T; Kitano M; Hashiya K; Kashiwazaki G; Sugiyama H
    Bioorg Med Chem; 2011 Oct; 19(19):5896-902. PubMed ID: 21903400
    [TBL] [Abstract][Full Text] [Related]  

  • 37. 5-Amino-1-(chloromethyl)-1,2-dihydro-3H-benz[e]indoles: relationships between structure and cytotoxicity for analogues bearing different DNA minor groove binding subunits.
    Atwell GJ; Milbank JJ; Wilson WR; Hogg A; Denny WA
    J Med Chem; 1999 Aug; 42(17):3400-11. PubMed ID: 10464026
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Sequence-selective single-molecule alkylation with a pyrrole-imidazole polyamide visualized in a DNA nanoscaffold.
    Yoshidome T; Endo M; Kashiwazaki G; Hidaka K; Bando T; Sugiyama H
    J Am Chem Soc; 2012 Mar; 134(10):4654-60. PubMed ID: 22320236
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Unsymmetrical DNA cross-linking agents: combination of the CBI and PBD pharmacophores.
    Tercel M; Stribbling SM; Sheppard H; Siim BG; Wu K; Pullen SM; Botting KJ; Wilson WR; Denny WA
    J Med Chem; 2003 May; 46(11):2132-51. PubMed ID: 12747786
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Cell permeability of Py-Im-polyamide-fluorescein conjugates: Influence of molecular size and Py/Im content.
    Nishijima S; Shinohara K; Bando T; Minoshima M; Kashiwazaki G; Sugiyama H
    Bioorg Med Chem; 2010 Jan; 18(2):978-83. PubMed ID: 20022508
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.