522 related articles for article (PubMed ID: 18033773)
1. Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade.
Tavolari S; Bonafè M; Marini M; Ferreri C; Bartolini G; Brighenti E; Manara S; Tomasi V; Laufer S; Guarnieri T
Carcinogenesis; 2008 Feb; 29(2):371-80. PubMed ID: 18033773
[TBL] [Abstract][Full Text] [Related]
2. Licofelone, a novel 5-LOX/COX-inhibitor, attenuates leukocyte rolling and adhesion on endothelium under flow.
Ulbrich H; Soehnlein O; Xie X; Eriksson EE; Lindbom L; Albrecht W; Laufer S; Dannhardt G
Biochem Pharmacol; 2005 Jul; 70(1):30-6. PubMed ID: 15894291
[TBL] [Abstract][Full Text] [Related]
3. Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors.
Hong SH; Avis I; Vos MD; Martínez A; Treston AM; Mulshine JL
Cancer Res; 1999 May; 59(9):2223-8. PubMed ID: 10232612
[TBL] [Abstract][Full Text] [Related]
4. Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke.
Ye YN; Wu WK; Shin VY; Bruce IC; Wong BC; Cho CH
Carcinogenesis; 2005 Apr; 26(4):827-34. PubMed ID: 15637091
[TBL] [Abstract][Full Text] [Related]
5. Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells.
Sun Y; Tang XM; Half E; Kuo MT; Sinicrope FA
Cancer Res; 2002 Nov; 62(21):6323-8. PubMed ID: 12414664
[TBL] [Abstract][Full Text] [Related]
6. Anticancer effects of licofelone (ML-3000) in prostate cancer cells.
Narayanan NK; Nargi D; Attur M; Abramson SB; Narayanan BA
Anticancer Res; 2007; 27(4B):2393-402. PubMed ID: 17695530
[TBL] [Abstract][Full Text] [Related]
7. The effects of TNF-alpha and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status.
Kovaríková M; Hofmanová J; Soucek K; Kozubík A
Differentiation; 2004 Feb; 72(1):23-31. PubMed ID: 15008823
[TBL] [Abstract][Full Text] [Related]
8. Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation.
Rotondo S; Krauze-Brzósko K; Manarini S; Evangelista V; Cerletti C
Eur J Pharmacol; 2004 Mar; 488(1-3):79-83. PubMed ID: 15044038
[TBL] [Abstract][Full Text] [Related]
9. 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells.
Shureiqi I; Chen D; Lotan R; Yang P; Newman RA; Fischer SM; Lippman SM
Cancer Res; 2000 Dec; 60(24):6846-50. PubMed ID: 11156377
[TBL] [Abstract][Full Text] [Related]
10. Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.
Marcouiller P; Pelletier JP; Guévremont M; Martel-Pelletier J; Ranger P; Laufer S; Reboul P
J Rheumatol; 2005 Apr; 32(4):704-12. PubMed ID: 15801029
[TBL] [Abstract][Full Text] [Related]
11. Licofelone, a balanced inhibitor of cyclooxygenase and 5-lipoxygenase, reduces inflammation in a rabbit model of atherosclerosis.
Vidal C; Gómez-Hernández A; Sánchez-Galán E; González A; Ortega L; Gómez-Gerique JA; Tuñón J; Egido J
J Pharmacol Exp Ther; 2007 Jan; 320(1):108-16. PubMed ID: 17015640
[TBL] [Abstract][Full Text] [Related]
12. 5-Lipoxygenase inhibitors attenuate growth of human renal cell carcinoma and induce apoptosis through arachidonic acid pathway.
Matsuyama M; Yoshimura R; Mitsuhashi M; Tsuchida K; Takemoto Y; Kawahito Y; Sano H; Nakatani T
Oncol Rep; 2005 Jul; 14(1):73-9. PubMed ID: 15944770
[TBL] [Abstract][Full Text] [Related]
13. Licofelone--clinical update on a novel LOX/COX inhibitor for the treatment of osteoarthritis.
Alvaro-Gracia JM
Rheumatology (Oxford); 2004 Feb; 43 Suppl 1():i21-5. PubMed ID: 14752172
[TBL] [Abstract][Full Text] [Related]
14. The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway.
Boileau C; Pelletier JP; Tardif G; Fahmi H; Laufer S; Lavigne M; Martel-Pelletier J
Ann Rheum Dis; 2005 Jun; 64(6):891-8. PubMed ID: 15498796
[TBL] [Abstract][Full Text] [Related]
15. Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model.
Melstrom LG; Bentrem DJ; Salabat MR; Kennedy TJ; Ding XZ; Strouch M; Rao SM; Witt RC; Ternent CA; Talamonti MS; Bell RH; Adrian TA
Clin Cancer Res; 2008 Oct; 14(20):6525-30. PubMed ID: 18927292
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of 5-lipoxygenase pathway suppresses the growth of bladder cancer cells.
Hayashi T; Nishiyama K; Shirahama T
Int J Urol; 2006 Aug; 13(8):1086-91. PubMed ID: 16903934
[TBL] [Abstract][Full Text] [Related]
17. The decrease of cell membrane fluidity by the non-steroidal anti-inflammatory drug Licofelone inhibits epidermal growth factor receptor signalling and triggers apoptosis in HCA-7 colon cancer cells.
Tavolari S; Munarini A; Storci G; Laufer S; Chieco P; Guarnieri T
Cancer Lett; 2012 Aug; 321(2):187-94. PubMed ID: 22343320
[TBL] [Abstract][Full Text] [Related]
18. Licofelone (ML-3000), a dual inhibitor of 5-lipoxygenase and cyclooxygenase, reduces the level of cartilage chondrocyte death in vivo in experimental dog osteoarthritis: inhibition of pro-apoptotic factors.
Boileau C; Martel-Pelletier J; Jouzeau JY; Netter P; Moldovan F; Laufer S; Tries S; Pelletier JP
J Rheumatol; 2002 Jul; 29(7):1446-53. PubMed ID: 12136904
[TBL] [Abstract][Full Text] [Related]
19. The lipoxygenase-cyclooxygenase inhibitor licofelone prevents thromboxane A2-mediated cardiovascular derangement triggered by the inflammatory peptide fMLP in the rabbit.
Rotondo S; Dell'Elba G; Manarini S; Cerletti C; Evangelista V
Eur J Pharmacol; 2006 Sep; 546(1-3):95-101. PubMed ID: 16920097
[TBL] [Abstract][Full Text] [Related]
20. Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids.
Martel-Pelletier J; Mineau F; Fahmi H; Laufer S; Reboul P; Boileau C; Lavigne M; Pelletier JP
Arthritis Rheum; 2004 Dec; 50(12):3925-33. PubMed ID: 15593193
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
