477 related articles for article (PubMed ID: 18035532)
1. Drug discovery beyond the 'rule-of-five'.
Zhang MQ; Wilkinson B
Curr Opin Biotechnol; 2007 Dec; 18(6):478-88. PubMed ID: 18035532
[TBL] [Abstract][Full Text] [Related]
2. Molecular properties that influence oral drug-like behavior.
Lajiness MS; Vieth M; Erickson J
Curr Opin Drug Discov Devel; 2004 Jul; 7(4):470-7. PubMed ID: 15338956
[TBL] [Abstract][Full Text] [Related]
3. A practical view of 'druggability'.
Keller TH; Pichota A; Yin Z
Curr Opin Chem Biol; 2006 Aug; 10(4):357-61. PubMed ID: 16814592
[TBL] [Abstract][Full Text] [Related]
4. Developing a drug-like natural product library.
Quinn RJ; Carroll AR; Pham NB; Baron P; Palframan ME; Suraweera L; Pierens GK; Muresan S
J Nat Prod; 2008 Mar; 71(3):464-8. PubMed ID: 18257534
[TBL] [Abstract][Full Text] [Related]
5. Improving drug candidates by design: a focus on physicochemical properties as a means of improving compound disposition and safety.
Meanwell NA
Chem Res Toxicol; 2011 Sep; 24(9):1420-56. PubMed ID: 21790149
[TBL] [Abstract][Full Text] [Related]
6. Rational approaches to natural-product-based drug design.
Haustedt LO; Mang C; Siems K; Schiewe H
Curr Opin Drug Discov Devel; 2006 Jul; 9(4):445-62. PubMed ID: 16889228
[TBL] [Abstract][Full Text] [Related]
7. Drug and drug candidate building block analysis.
Wang J; Hou T
J Chem Inf Model; 2010 Jan; 50(1):55-67. PubMed ID: 20020714
[TBL] [Abstract][Full Text] [Related]
8. Drug discovery and natural products: end of an era or an endless frontier?
Li JW; Vederas JC
Science; 2009 Jul; 325(5937):161-5. PubMed ID: 19589993
[TBL] [Abstract][Full Text] [Related]
9. 'Metabolite-likeness' as a criterion in the design and selection of pharmaceutical drug libraries.
Dobson PD; Patel Y; Kell DB
Drug Discov Today; 2009 Jan; 14(1-2):31-40. PubMed ID: 19049901
[TBL] [Abstract][Full Text] [Related]
10. Natural products as catalysts for innovation: a pharmaceutical industry perspective.
Schmitt EK; Moore CM; Krastel P; Petersen F
Curr Opin Chem Biol; 2011 Aug; 15(4):497-504. PubMed ID: 21684800
[TBL] [Abstract][Full Text] [Related]
11. Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes.
McConnell O; Bach A; Balibar C; Byrne N; Cai Y; Carter G; Chlenov M; Di L; Fan K; Goljer I; He Y; Herold D; Kagan M; Kerns E; Koehn F; Kraml C; Marathias V; Marquez B; McDonald L; Nogle L; Petucci C; Schlingmann G; Tawa G; Tischler M; Williamson RT; Sutherland A; Watts W; Young M; Zhang MY; Zhang Y; Zhou D; Ho D
Chirality; 2007 Sep; 19(9):658-82. PubMed ID: 17390370
[TBL] [Abstract][Full Text] [Related]
12. HTS technologies in biopharmaceutical discovery.
Wu G; Doberstein SK
Drug Discov Today; 2006 Aug; 11(15-16):718-24. PubMed ID: 16846799
[TBL] [Abstract][Full Text] [Related]
13. Timely synthetic support for medicinal chemists.
Potoski J
Drug Discov Today; 2005 Jan; 10(2):115-20. PubMed ID: 15718160
[TBL] [Abstract][Full Text] [Related]
14. [Strategy of molecular drug design: hits, leads and drug candidates].
Guo ZR
Yao Xue Xue Bao; 2008 Sep; 43(9):898-904. PubMed ID: 19048779
[TBL] [Abstract][Full Text] [Related]
15. Dependence of molecular properties on proteomic family for marketed oral drugs.
Vieth M; Sutherland JJ
J Med Chem; 2006 Jun; 49(12):3451-3. PubMed ID: 16759087
[TBL] [Abstract][Full Text] [Related]
16. Implementation of BacMam virus gene delivery technology in a drug discovery setting.
Kost TA; Condreay JP; Ames RS; Rees S; Romanos MA
Drug Discov Today; 2007 May; 12(9-10):396-403. PubMed ID: 17467576
[TBL] [Abstract][Full Text] [Related]
17. Solid form screening--a review.
Aaltonen J; Allesø M; Mirza S; Koradia V; Gordon KC; Rantanen J
Eur J Pharm Biopharm; 2009 Jan; 71(1):23-37. PubMed ID: 18715549
[TBL] [Abstract][Full Text] [Related]
18. A screening study of ChirBase molecular database to explore the expanded chiral pool derived from the application of chiral chromatography.
Piras P; Roussel C
J Pharm Biomed Anal; 2008 Apr; 46(5):839-47. PubMed ID: 17942261
[TBL] [Abstract][Full Text] [Related]
19. Knowledge-based chemoinformatic approaches to drug discovery.
Ghose AK; Herbertz T; Salvino JM; Mallamo JP
Drug Discov Today; 2006 Dec; 11(23-24):1107-14. PubMed ID: 17129830
[TBL] [Abstract][Full Text] [Related]
20. A decade of fragment-based drug design: strategic advances and lessons learned.
Hajduk PJ; Greer J
Nat Rev Drug Discov; 2007 Mar; 6(3):211-9. PubMed ID: 17290284
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
