These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 18035829)

  • 1. Synthesis and anti-HIV evaluation of hybrid-type prodrugs conjugating HIV integrase inhibitors with d4t by self-cleavable spacers containing an amino acid residue.
    Fossey C; Huynh NT; Vu AH; Vidu A; Zarafu I; Laduree D; Schmidt S; Laumond G; Aubertin AM
    J Enzyme Inhib Med Chem; 2007 Oct; 22(5):608-19. PubMed ID: 18035829
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of prodrug-type anti-HIV agents conjugating a REVERSE transcriptase inhibitor to a HIV-1 integrase inhibitor by a spontaneously cleavable linker.
    Fossey C; Vu AH; Vidu A; Zarafu I; Laduree D; Schmidt S; Laumond G; Aubertin AM
    J Enzyme Inhib Med Chem; 2007 Oct; 22(5):591-607. PubMed ID: 18035828
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potential multifunctional inhibitors of HIV-1 reverse transcriptase. Novel [AZT]-[TSAO-T] and [d4T]-[TSAO-T] heterodimers modified in the linker and in the dideoxynucleoside region.
    Velázquez S; Tuñón V; Jimeno ML; Chamorro C; De Clercq E; Balzarini J; Camarasa MJ
    J Med Chem; 1999 Dec; 42(25):5188-96. PubMed ID: 10602704
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and anti-HIV activity of some [Nucleoside Reverse Transcriptase Inhibitor]-C5'-linker-[Integrase Inhibitor] heterodimers as inhibitors of HIV replication.
    Sugeac E; Fossey C; Ladurée D; Schmidt S; Laumond G; Aubertin AM
    J Enzyme Inhib Med Chem; 2004 Dec; 19(6):497-509. PubMed ID: 15662954
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and anti-HIV activity of [d4U]-[trovirdine analogue] and [d4T]-[trovirdine analogue] heterodimers as inhibitors of HIV-1 reverse transcriptase.
    Gavriliu D; Fossey C; Ciurea A; Delbederi Z; Sugeac E; Ladurée D; Schmidt S; Laumond G; Aubertin AM
    Nucleosides Nucleotides Nucleic Acids; 2002; 21(8-9):505-33. PubMed ID: 12484448
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of lipophilic phosphoramidate d4T-MP prodrugs expressing high potency against HIV in cell culture: structural determinants for in vitro activity and QSAR.
    Siddiqui AQ; McGuigan C; Ballatore C; Zuccotto F; Gilbert IH; De Clercq E; Balzarini J
    J Med Chem; 1999 Oct; 42(20):4122-8. PubMed ID: 10514282
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase.
    Sun L; Gao P; Dong G; Zhang X; Cheng X; Ding X; Wang X; Daelemans D; De Clercq E; Pannecouque C; Menéndez-Arias L; Zhan P; Liu X
    Eur J Med Chem; 2018 Jul; 155():714-724. PubMed ID: 29940462
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of double-prodrugs against HIV. Conjugation of D4T with 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach.
    Petersen L; Jørgensen PT; Nielsen C; Hansen TH; Nielsen J; Pedersen EB
    J Med Chem; 2005 Feb; 48(4):1211-20. PubMed ID: 15715487
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, anti-human immunodeficiency virus activity and esterase lability of some novel carboxylic ester-modified phosphoramidate derivatives of stavudine (d4T).
    McGuigan C; Sutton PW; Cahard D; Turner K; O'Leary G; Wang Y; Gumbleton M; De Clercq E; Balzarini J
    Antivir Chem Chemother; 1998 Nov; 9(6):473-9. PubMed ID: 9865385
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and anti-HIV activity of some heterodimers [NRTI]-glycyl-succinyl-[trovirdine analogue] of known HIV-1 reverse transcriptase inhibitors.
    Sugeac E; Fossey C; Ladurée D; Schmidt S; Laumond G; Aubertin AM
    J Enzyme Inhib Med Chem; 2003 Apr; 18(2):175-86. PubMed ID: 12943202
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Strategies in the design of prodrugs of anti-HIV agents.
    Calogeropoulou T; Detsi A; Lekkas E; Koufaki M
    Curr Top Med Chem; 2003; 3(13):1467-95. PubMed ID: 14529522
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolism and anti-HIV activity of phosphoramidate derivatives of D4T-MP with variations in the amino acid moiety.
    Naesens L; Cahard D; Salgado A; Bidois L; De Clercq E; McGuigan C; Balzarini J
    Adv Exp Med Biol; 1998; 431():753-7. PubMed ID: 9598164
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deoxyribonucleoside 2'- or 3'-mixed disulfides: prodrugs to target ribonucleotide reductase and/or to inhibit HIV reverse transcription.
    Roy B; Chambert S; Lepoivre M; Aubertin AM; Balzarini J; Décout JL
    J Med Chem; 2003 Jun; 46(13):2565-8. PubMed ID: 12801219
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of 5-alkynylated d4T analogues as potential HIV-1 reverse transcriptase inhibitors.
    Ciurea A; Fossey C; Gavriliu D; Delbederi Z; Sugeac E; Laduree D; Schmidt S; Laumond G; Aubertin AM
    J Enzyme Inhib Med Chem; 2004 Dec; 19(6):511-9. PubMed ID: 15662955
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and anti-HIV activity of cyclic pyrimidine phosphonomethoxy nucleosides and their prodrugs: a comparison of phosphonates and corresponding nucleosides.
    Mackman RL; Zhang L; Prasad V; Boojamra CG; Chen J; Douglas J; Grant D; Laflamme G; Hui H; Kim CU; Parrish J; Stoycheva AD; Swaminathan S; Wang K; Cihlar T
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(6-7):573-7. PubMed ID: 18066858
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, stability, and biological evaluation of 1,3-dihydrobenzo[c]furan analogue of d4T and its SATE pronucleotide.
    Len C; Selouane A; Postel D; Villa P; Aubertin AM; Egron D; Gosselin G; Périgaud C
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):943-5. PubMed ID: 14565317
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bis-ketol nucleoside triesters as prodrugs of the antiviral nucleoside triphosphate analogues of 3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine.
    Calvo KC; Wang X; Koser GF
    Nucleosides Nucleotides Nucleic Acids; 2004; 23(3):637-46. PubMed ID: 15113029
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors.
    Thomas MG; Maga G; Mouscadet JF; Howarth NM
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):1063-6. PubMed ID: 18058537
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacophore and structure-activity relationships of integrase inhibition within a dual inhibitor scaffold of HIV reverse transcriptase and integrase.
    Wang Z; Tang J; Salomon CE; Dreis CD; Vince R
    Bioorg Med Chem; 2010 Jun; 18(12):4202-11. PubMed ID: 20576573
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, nanosizing and in vitro drug release of a novel anti-HIV polymeric prodrug: chitosan-O-isopropyl-5'-O-d4T monophosphate conjugate.
    Yang L; Chen L; Zeng R; Li C; Qiao R; Hu L; Li Z
    Bioorg Med Chem; 2010 Jan; 18(1):117-23. PubMed ID: 19959368
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.